Fibroblast Growth Factor Receptor | Protein Tyrosine Kinase/RTK| CSNpharm

FGFR

FGFR
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货号	产品名	CAS号	信息
CSN12916	PD173074	219580-11-7	PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM, ~1000-fold selective for FGFR1 than PDGFR and c-Src.
CSN13927	PD166866	192705-79-6	PD 166866 is a selective FGFR tyrosine kinase inhibitor with an IC50 of 52.4 nM.
CSN23025	PD 166285 2HCl	212391-63-4	PD 166285 inhibited Src nonreceptor tyrosine kinase, fibroblast growth factor receptor-1, epidermal growth factor receptor and platelet-derived growth factor receptor beta subunit (PDGFR-beta), tyrosine kinases with half-maximal inhibitory potencies (IC50 values) of 8.4 +/- 2.3 nM (n = 6), 39.3 +/- 2.8 nM (n = 16), 87.5 +/- 13.7 nM (n = 6) and 98.3 +/- 7.9 nM (n = 16), respectively.
CSN23024	PD 161570	192705-80-9	PD 161570 is a selective FGFR inhibitor with IC50 of 40 nM.
CSN26650	ARQ 069	1314021-57-2	and 1.23 μM, respectively). ARQ 069 inhibits FGFR1/FGFR2 autophosphorylation (IC50s of 2.8 and 1.9 μM, respectively) through a mechanism in a non-ATP competitive dependent manner[1].
CSN12169	AG 1296	146535-11-7	AG 1296 is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR. It also inhibits FGFR and c-Kit with IC50 of 12.3 μM and 1.8 μM in Swiss 3T3 cells.
CSN33244	Methyl 7-chloro-4-(4-methoxybenzyl)-2-methyl-5-oxo-4,5-dihydro-2H-pyrazolo[4,3-b]pyridine-6-carboxylate	2338863-43-5