400-920-2911 sales@csnpharm.cn
Glucagon Receptor
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN27220 | Teduglutide | 197922-42-2 | Teduglutide , an analog of glucagon-like peptide 2, improves intestinal rehabilitation by promoting mucosal growth and possibly by inhibiting gastric emptying and secretion, which in turn reduces intestinal losses and promotes intestinal absorption. |
CSN18992 | Taspoglutide | 275371-94-3 | Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist developed for treatment of type 2 diabetes, with an EC50 value of 0.06 nM. |
CSN26148 | (S)-2,2',4,4',5,5'-Hexahydroxy-7,7'-dimethyl-[1,1'-bianthracene]-9,9',10,10'-tetraone | 602-06-2 | Skyrin is a fungal bisanthroquinone. It exhibits functional glucagon antagonism by uncoupling the glucagon receptor from adenylate cyclase activation in rat liver membranes. |
CSN21104 | Semaglutide | 910463-68-2 | Semaglutide is an analog of human GLP-1 with long-acting effect over the other GLP-1Ras. |
CSN25223 | Danuglipron (PF-06882961) | 2230198-02-2 | PF-06882961 is a potent and orally bioavailable GLP-1R agonist. |
CSN13565 | MK 0893 | 870823-12-4 | MK 0893 is a potent, selective glucagon receptor antagonist with IC50 of 6.6 nM, showing > 200 fold selectivity for GIPR, PAC1, GLP-1R, VPAC1 and VPAC2. |
CSN23829 | Lixisenatide | 320367-13-3 | Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM). |
CSN11311 | Liraglutide | 204656-20-2 | Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus. |
CSN23794 | LGD-6972 | 1207989-09-0 | LGD-6972 is a novel and orally-available glucagon receptor antagonist used to treat type 2 diabetes mellitus in Phase 1 study. |
CSN22875 | L-168049 | 191034-25-0 | L-168,049 is a very potent and selective, non-competitive antagonist of the human glucagon receptor with IC50 of 3.7 nM. |
CSN18988 | GRA Ex-25 | 307983-31-9 | GRA Ex-25 is an inhibitor of glucagon receptor, with IC50 of 56 and 55 nM for rat and human glucagon receptors, respectively. |
CSN17234 | PF-06291874 | 1393124-08-7 | Glucagon receptor antagonists-4 is an selective antagonist of glucagon receptor. |
CSN18088 | Glucagon receptor antagonists-3 | 202917-17-7 | Glucagon receptor antagonists-3 is a highly potent glucagon receptor antagonist. |
CSN18089 | Glucagon receptor antagonists-2 | 202917-18-8 | Glucagon receptor antagonists-2 is a highly potent glucagon receptor antagonist. |
CSN13173 | Glucagon receptor antagonists-1 | 503559-84-0 | Glucagon receptor antagonists-1 is a highly potent glucagon receptor antagonist. |
CSN11104 | Glucagon (1-29), bovine, human, porcine | 16941-32-5 | Glucagon is a peptide hormone, exhibits therapeutic potential for metabolic disease. |
CSN18991 | GLP-1(7-37) | 106612-94-6 | GLP-1(7-37) is an insulinotropic peptide generated from the precursor peptide GLP-1(1-37). |
CSN24282 | GLP-1(7-37) TFA salt | 725250-02-2 | GLP-1(7-37) is an insulinotropic peptide generated from the precursor peptide GLP-1(1-37). |
CSN19866 | Exendin-4 | 141758-74-9 | Exendin-4 is a high affinity glucagon-like peptide 1 (GLP-1) receptor agonist (Kd = 136 pM) and originally isolated from Heloderma suspectum venom. |
CSN18568 | Exendin-4 acetate | 914454-01-6 | Exendin-4 acetate is a 39 amino acid peptide, activates GLP-1 (glucagon-like peptide-1) receptors to increase intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors. |
CSN21499 | Avexitide | 133514-43-9 | Exendin Fragment 9-39 is an antagonist of glucagon-like peptide-1 (GLP-1) receptor, and also acts as an inhibitor of glucosedependent insulinotropic polypeptide (GIP)-receptor binding. |
CSN22077 | BETP | 1371569-69-5 | BETP is an agonist of glucagon-like peptide-1 (GLP-1) receptor, with EC50s of 0.66 and 0.755 μM for human and rat GLP-1 receptor, respectively. |
CSN17364 | Adomeglivant | 1488363-78-5 | Adomeglivant is a potent and selective glucagon receptor antagonist that is used in clinical trial for type 2 diabetes mellitus. |