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Glucagon Receptor

Glucagon Receptor

货号 产品名 CAS号 信息
CSN27220 Teduglutide 197922-42-2 Teduglutide , an analog of glucagon-like peptide 2, improves intestinal rehabilitation by promoting mucosal growth and possibly by inhibiting gastric emptying and secretion, which in turn reduces intestinal losses and promotes intestinal absorption.
CSN18992 Taspoglutide 275371-94-3 Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist developed for treatment of type 2 diabetes, with an EC50 value of 0.06 nM.
CSN26148 (S)-2,2',4,4',5,5'-Hexahydroxy-7,7'-dimethyl-[1,1'-bianthracene]-9,9',10,10'-tetraone 602-06-2 Skyrin is a fungal bisanthroquinone. It exhibits functional glucagon antagonism by uncoupling the glucagon receptor from adenylate cyclase activation in rat liver membranes.
CSN21104 Semaglutide 910463-68-2 Semaglutide is an analog of human GLP-1 with long-acting effect over the other GLP-1Ras.
CSN25223 Danuglipron (PF-06882961)   2230198-02-2 PF-06882961 is a potent and orally bioavailable GLP-1R agonist.
CSN13565 MK 0893 870823-12-4 MK 0893 is a potent, selective glucagon receptor antagonist with IC50 of 6.6 nM, showing > 200 fold selectivity for GIPR, PAC1, GLP-1R, VPAC1 and VPAC2.
CSN23829 Lixisenatide 320367-13-3 Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM).
CSN11311 Liraglutide 204656-20-2 Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.
CSN23794 LGD-6972 1207989-09-0 LGD-6972 is a novel and orally-available glucagon receptor antagonist used to treat type 2 diabetes mellitus in Phase 1 study.
CSN22875 L-168049 191034-25-0 L-168,049 is a very potent and selective, non-competitive antagonist of the human glucagon receptor with IC50 of 3.7 nM.
CSN18988 GRA Ex-25 307983-31-9 GRA Ex-25 is an inhibitor of glucagon receptor, with IC50 of 56 and 55 nM for rat and human glucagon receptors, respectively.
CSN17234 PF-06291874 1393124-08-7 Glucagon receptor antagonists-4 is an selective antagonist of glucagon receptor.
CSN18088 Glucagon receptor antagonists-3 202917-17-7 Glucagon receptor antagonists-3 is a highly potent glucagon receptor antagonist.
CSN18089 Glucagon receptor antagonists-2 202917-18-8 Glucagon receptor antagonists-2 is a highly potent glucagon receptor antagonist.
CSN13173 Glucagon receptor antagonists-1 503559-84-0 Glucagon receptor antagonists-1 is a highly potent glucagon receptor antagonist.
CSN11104 Glucagon (1-29), bovine, human, porcine 16941-32-5 Glucagon is a peptide hormone, exhibits therapeutic potential for metabolic disease.
CSN18991 GLP-1(7-37) 106612-94-6 GLP-1(7-37) is an insulinotropic peptide generated from the precursor peptide GLP-1(1-37).
CSN24282 GLP-1(7-37) TFA salt 725250-02-2 GLP-1(7-37) is an insulinotropic peptide generated from the precursor peptide GLP-1(1-37).
CSN19866 Exendin-4 141758-74-9 Exendin-4 is a high affinity glucagon-like peptide 1 (GLP-1) receptor agonist (Kd = 136 pM) and originally isolated from Heloderma suspectum venom.
CSN18568 Exendin-4 acetate 914454-01-6 Exendin-4 acetate is a 39 amino acid peptide, activates GLP-1 (glucagon-like peptide-1) receptors to increase intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors.
CSN21499 Avexitide 133514-43-9 Exendin Fragment 9-39 is an antagonist of glucagon-like peptide-1 (GLP-1) receptor, and also acts as an inhibitor of glucosedependent insulinotropic polypeptide (GIP)-receptor binding.
CSN22077 BETP 1371569-69-5 BETP is an agonist of glucagon-like peptide-1 (GLP-1) receptor, with EC50s of 0.66 and 0.755 μM for human and rat GLP-1 receptor, respectively.
CSN17364 Adomeglivant 1488363-78-5 Adomeglivant is a potent and selective glucagon receptor antagonist that is used in clinical trial for type 2 diabetes mellitus.
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