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CAR

货号 产品名 CAS号 信息
CSN26384 1,4-Bis((3,5-dichloropyridin-2-yl)oxy)benzene 76150-91-9 TCPOBOP is a constitutive androstane receptor (CAR) agonist that induces robust hepatocyte proliferation and hepatomegaly without any liver injury or tissue loss[1]. TCPOBOP attenuates Fas-induced murine liver injury by altering Bcl-2 proteins[2].
CSN19741 PK11195 85532-75-8 PK11195 is a 2‑Phenylindolylglyoxylyldipeptide Murine Double Minute2 (MDM2)/Translocator Protein (TSPO)/Human Constitutive Androstane Receptor (hCAR) Inhibitor, and is potentially useful for the Treatment of Gliomas.
CSN26394 CITCO 338404-52-7 CITCO, an imidazothiazole derivative, is a selective Constitutive androstane receptor (CAR) agonist. It inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors[1].
CSN23907 CINPA 1 102636-74-8 CINPA1 is a CAR inhibitor capable of reducing CAR-mediated transcription with an IC50 of ∼70 nM.
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