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HCV

HCV

货号 产品名 CAS号 信息
CSN19284 Voxilaprevir 1535212-07-7 Voxilaprevir is used for the treatment of Hepatitis C virus infection.
CSN18586 Vaniprevir 923590-37-8 Vaniprevir is a non-covalent competitive inhibitor of the hepatitis C virus (HCV) NS3/4A protease.
CSN26660 Valopicitabine 640281-90-9 Valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine, acts as a promising antiviral agent for reasearch of chronic HCV infection[1].
CSN19730 Uprifosbuvir 1496551-77-9 Uprifosbuvir is an uridine nucleotide analog HCV NS5B polymerase inhibitor.
CSN27518 Tris(4-aminophenyl)methane 548-61-8 Tris(4-aminophenyl)methane is a triphenylmethane dye. Tris(4-aminophenyl)methane is a weak HCV helicase inhibitor.
CSN18806 TMC647055 Choline 1204416-97-6 TMC647055 choline is a cell-permeating, selective HCV NS5B inhibitor, eliciting a mean IC50 of 34 nM, as assessed in the RdRp primer-dependent transcription assay.
CSN18867 Inarigivir soproxil 942123-43-5 SB-9200 has a broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus and influenza and has demonstrated activity against hepatitis B virus (HBV) in vitro and in vivo.
CSN19678 Ruzasvir 1613081-64-3 Ruzasvir is a potent, Pan-Genotype HCV NS5A inhibitor with Optimized activity against common resistance-associated polymorphisms.
CSN13587 Ritonavir   155213-67-5 Ritonavir is both an HIV protease inhibitor and a Cytochrome P450 3A inhibitor.
CSN21928 PSI-7409 1015073-42-3 PSI-7409 is the active 5′-triphosphate metabolite of PSI-7851 which is a selective and highly active nucleotide analog inhibitor of HCV.
CSN11778 Procyanidin B1 20315-25-7 Procyanidin B1, a natrual product isolated and prufied from the fruits of Vitis vinifera L., inhibits infection by vesicular stomatitis virus and HCV pseudotype virus in Huh-7 cells, with IC50 of 29μM and 15μM, respectively.
CSN19731 Pibrentasvir (ABT-530) 1353900-92-1 Pibrentasvir is a protease inhibitor potentially for the treatment of HCV infection.
CSN18776 NM107 20724-73-6 NM107 is an inhibitor of HCV RNA replication with IC50 of 7.0 μM.
CSN18498 Narlaprevir 865466-24-6 Narlaprevir is a potent, selective, orally bioavailable NS3 protease inhibitor (Ki=6 nM; EC90=40 nM).
CSN20487 MK-8876 1426960-33-9 MK-8876 is a HCV NS5B Site D Inhibitor.
CSN17832 Grazoprevir sodium salt 1425038-27-2 MK-5172 sodium is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.
CSN17558 Grazoprevir potassium salt 1206524-86-8 MK-5172 potassium is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.
CSN17729 Grazoprevir hydrate 1350462-55-3 MK-5172 is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.
CSN25415 Mecarbinate 15574-49-9 Mecarbinate is an anti-hepatitis C virus (HCV) agent.
CSN17899 Ledipasvir D-tartrate 1502654-87-6 Ledipasvir D-tartrate is an inhibitor of the hepatitis C virus NS5A protein, which is an experimental drug for the treatment of hepatitis C.
CSN18891 KIN1408 1903800-11-2 KIN1408 is an antiviral small molecule compound, as agonists of the RLR pathway.
CSN22150 JTK-853 954389-09-4 JTK-853 is a novel, non-nucleoside Hepatitis C Virus (HCV) polymerase inhibitor which shows effective antiviral activity in HCV replicon cells with EC50s of 0.38 and 0.035 µM in genotype 1a H77 and 1b Con1 strains, respectively.
CSN19807 IDX184 1036915-08-8 IDX 184 is an RNA-directed RNA polymerase (NS5B) inhibitor potentially for the treatment of HCV infection.
CSN27516 HCV-IN-30 1007882-23-6 HCV-IN-30 (compound 48) is a HCV NS5A replication complex inhibitor, with IC50s of 901 and 102 nM for genotypes 1a and 1b replicons, respectively.
CSN27517 HCV-IN-29 1009119-83-8 HCV-IN-29 is a hepatitis C virus (HCV) inhibitor exacted from patent US8329159B2, compound 1e.
CSN20438 GSK8175 1423007-82-2 GSK2878175 is a pan-genotypic non-nucleoside NS5B polymerase inhibitor potentially for the treatment of HCV infection.
CSN20249 GSK-2336805 1256390-53-0 GSK-2336805 is a HCV NS5A inhibitor potentially for the treatment of HCV infection.
CSN20645 Glecaprevir 1365970-03-1 Glecaprevir is a NS 3/4A inhibitor potentially for the treatment of HCV.
CSN14040 γ-Fagarine 524-15-2 gamma-Fagarine, a natural product isolated and purified from the fruits of Zanthoxylum simulans Hance, possessed moderate levels of anti-HCV activities.
CSN21653 Furaprofen 67700-30-5 Furaprofen is an inhibitor of HCV replication and it is substantially more potent against genotype 1a and 1b replicons (EC50 ≈ 30 nM) than genotype 2a (EC50 ≈ 1 μM).
CSN32904 Furaprevir 1435923-88-8 Furaprevir is a Serine Protease NS3/Non-Structural Protein 4A (NS3/NS4A) inhibitor.
CSN51111 Methyl ((S)-1-((S)-2-(6-((1R,4S)-8-(4-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)phenyl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate bis(phosphate) 1959593-63-5 Emitasvir phosphate, a small-molecule inhibitor of HCV non-structural protein 5A (NS5A) developed by HEC Pharm, was approved in China in 2020 for the treatment of liver cirrhosis-free genotype 1 hepatitis C patients. The product is in phase III clinical development for the treatment of patients suffering from chronic genotype 1 hepatitis C, in a combination regimen with furaprevir and ribavirin.
CSN17757 Elbasvir 1370468-36-2 Elbasvir is an inhibitor of nonstructural protein 5A (NS5A) of hepatitis C virus (HCV). It can be used to treat chronic HCV infection.
CSN18471 Danoprevir 850876-88-9 Danoprevir, a peptidomimetic, is an inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2 nM - 3.5 nM.
CSN18886 Beclabuvir 958002-33-0 Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM.
CSN19317 Artemisinin 63968-64-9 Artemisinin is an inhibitor of HCV subgenomic replicon. It widely used as anti-malarial drug.
CSN27623 Antrodin A 656830-24-9 Antrodin A was isolated as one of the constituents of A. cinnamomea. It exhibited potent inhibitory activity on HCV protease with IC50 of 0.9μg/mL.
CSN18276 Anguizole 442666-98-0 Anguizole is a small molecule inhibitor of HCV replication and alters NS4B's subcellular distribution.
CSN20627 Alisporivir 254435-95-5 Alisporivir is a cyclophilin inhibitor molecule with potent anti-hepatitis C virus (HCV) activity.
CSN25386 AG-1478 hydrochloride 170449-18-0 AG-1478 hydrochloride (Tyrphostin AG-1478 hydrochloride) is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 hydrochloride has antiviral effects against HCV and encephalomyocarditis virus (EMCV).
CSN22160 ACH-806 870142-71-5 ACH-806 is an NS4A antagonist which can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.
CSN23603 4-Phenoxybenzylamine 107622-80-0 4-Phenoxybenzylamine can stabilize the NS3 protein in an inactive state with IC50 of 500 μM.
CSN60078 Bemnifosbuvir 1998705-64-8
CSN61906 Ledipasvir-d6 2050041-12-6
CSN51384 Bersacapavir 1638266-40-6
CSN51411 BMS-986144 1606150-08-6
CSN51417 GSK2818713 1422484-32-9
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