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HCV
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN19284 | Voxilaprevir | 1535212-07-7 | Voxilaprevir is used for the treatment of Hepatitis C virus infection. |
| CSN18586 | Vaniprevir | 923590-37-8 | Vaniprevir is a non-covalent competitive inhibitor of the hepatitis C virus (HCV) NS3/4A protease. |
| CSN26660 | Valopicitabine | 640281-90-9 | Valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine, acts as a promising antiviral agent for reasearch of chronic HCV infection[1]. |
| CSN19730 | Uprifosbuvir | 1496551-77-9 | Uprifosbuvir is an uridine nucleotide analog HCV NS5B polymerase inhibitor. |
| CSN27518 | Tris(4-aminophenyl)methane | 548-61-8 | Tris(4-aminophenyl)methane is a triphenylmethane dye. Tris(4-aminophenyl)methane is a weak HCV helicase inhibitor. |
| CSN18806 | TMC647055 Choline | 1204416-97-6 | TMC647055 choline is a cell-permeating, selective HCV NS5B inhibitor, eliciting a mean IC50 of 34 nM, as assessed in the RdRp primer-dependent transcription assay. |
| CSN18867 | Inarigivir soproxil | 942123-43-5 | SB-9200 has a broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus and influenza and has demonstrated activity against hepatitis B virus (HBV) in vitro and in vivo. |
| CSN19678 | Ruzasvir | 1613081-64-3 | Ruzasvir is a potent, Pan-Genotype HCV NS5A inhibitor with Optimized activity against common resistance-associated polymorphisms. |
| CSN13587 | Ritonavir | 155213-67-5 | Ritonavir is both an HIV protease inhibitor and a Cytochrome P450 3A inhibitor. |
| CSN21928 | PSI-7409 | 1015073-42-3 | PSI-7409 is the active 5′-triphosphate metabolite of PSI-7851 which is a selective and highly active nucleotide analog inhibitor of HCV. |
| CSN11778 | Procyanidin B1 | 20315-25-7 | Procyanidin B1, a natrual product isolated and prufied from the fruits of Vitis vinifera L., inhibits infection by vesicular stomatitis virus and HCV pseudotype virus in Huh-7 cells, with IC50 of 29μM and 15μM, respectively. |
| CSN19731 | Pibrentasvir (ABT-530) | 1353900-92-1 | Pibrentasvir is a protease inhibitor potentially for the treatment of HCV infection. |
| CSN18776 | NM107 | 20724-73-6 | NM107 is an inhibitor of HCV RNA replication with IC50 of 7.0 μM. |
| CSN18498 | Narlaprevir | 865466-24-6 | Narlaprevir is a potent, selective, orally bioavailable NS3 protease inhibitor (Ki=6 nM; EC90=40 nM). |
| CSN20487 | Mk-8876 | 1426960-33-9 | MK-8876 is a HCV NS5B Site D Inhibitor. |
| CSN17832 | Grazoprevir sodium salt | 1425038-27-2 | MK-5172 sodium is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development. |
| CSN17558 | Grazoprevir potassium salt | 1206524-86-8 | MK-5172 potassium is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development. |
| CSN17729 | Grazoprevir hydrate | 1350462-55-3 | MK-5172 is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development. |
| CSN25415 | Mecarbinate | 15574-49-9 | Mecarbinate is an anti-hepatitis C virus (HCV) agent. |
| CSN17899 | Ledipasvir D-tartrate | 1502654-87-6 | Ledipasvir D-tartrate is an inhibitor of the hepatitis C virus NS5A protein, which is an experimental drug for the treatment of hepatitis C. |
| CSN18891 | KIN1408 | 1903800-11-2 | KIN1408 is an antiviral small molecule compound, as agonists of the RLR pathway. |
| CSN22150 | JTK-853 | 954389-09-4 | JTK-853 is a novel, non-nucleoside Hepatitis C Virus (HCV) polymerase inhibitor which shows effective antiviral activity in HCV replicon cells with EC50s of 0.38 and 0.035 µM in genotype 1a H77 and 1b Con1 strains, respectively. |
| CSN19807 | IDX184 | 1036915-08-8 | IDX 184 is an RNA-directed RNA polymerase (NS5B) inhibitor potentially for the treatment of HCV infection. |
| CSN27516 | HCV-IN-30 | 1007882-23-6 | HCV-IN-30 (compound 48) is a HCV NS5A replication complex inhibitor, with IC50s of 901 and 102 nM for genotypes 1a and 1b replicons, respectively. |
| CSN27517 | HCV-IN-29 | 1009119-83-8 | HCV-IN-29 is a hepatitis C virus (HCV) inhibitor exacted from patent US8329159B2, compound 1e. |
| CSN20438 | GSK8175 | 1423007-82-2 | GSK2878175 is a pan-genotypic non-nucleoside NS5B polymerase inhibitor potentially for the treatment of HCV infection. |
| CSN20249 | Gsk-2336805 | 1256390-53-0 | GSK-2336805 is a HCV NS5A inhibitor potentially for the treatment of HCV infection. |
| CSN20645 | Glecaprevir | 1365970-03-1 | Glecaprevir is a NS 3/4A inhibitor potentially for the treatment of HCV. |
| CSN14040 | γ-Fagarine | 524-15-2 | gamma-Fagarine, a natural product isolated and purified from the fruits of Zanthoxylum simulans Hance, possessed moderate levels of anti-HCV activities. |
| CSN21653 | Furaprofen | 67700-30-5 | Furaprofen is an inhibitor of HCV replication and it is substantially more potent against genotype 1a and 1b replicons (EC50 ≈ 30 nM) than genotype 2a (EC50 ≈ 1 μM). |
| CSN32904 | Furaprevir | 1435923-88-8 | Furaprevir is a Serine Protease NS3/Non-Structural Protein 4A (NS3/NS4A) inhibitor. |
| CSN51111 | Methyl ((S)-1-((S)-2-(6-((1R,4S)-8-(4-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)phenyl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate bis(phosphate) | 1959593-63-5 | Emitasvir phosphate, a small-molecule inhibitor of HCV non-structural protein 5A (NS5A) developed by HEC Pharm, was approved in China in 2020 for the treatment of liver cirrhosis-free genotype 1 hepatitis C patients. The product is in phase III clinical development for the treatment of patients suffering from chronic genotype 1 hepatitis C, in a combination regimen with furaprevir and ribavirin. |
| CSN17757 | Elbasvir | 1370468-36-2 | Elbasvir is an inhibitor of nonstructural protein 5A (NS5A) of hepatitis C virus (HCV). It can be used to treat chronic HCV infection. |
| CSN18471 | Danoprevir | 850876-88-9 | Danoprevir, a peptidomimetic, is an inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2 nM - 3.5 nM. |
| CSN18886 | Beclabuvir | 958002-33-0 | Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM. |
| CSN19317 | Artemisinin | 63968-64-9 | Artemisinin is an inhibitor of HCV subgenomic replicon. It widely used as anti-malarial drug. |
| CSN27623 | Antrodin A | 656830-24-9 | Antrodin A was isolated as one of the constituents of A. cinnamomea. It exhibited potent inhibitory activity on HCV protease with IC50 of 0.9μg/mL. |
| CSN18276 | Anguizole | 442666-98-0 | Anguizole is a small molecule inhibitor of HCV replication and alters NS4B's subcellular distribution. |
| CSN20627 | Alisporivir | 254435-95-5 | Alisporivir is a cyclophilin inhibitor molecule with potent anti-hepatitis C virus (HCV) activity. |
| CSN25386 | AG-1478 hydrochloride | 170449-18-0 | AG-1478 hydrochloride (Tyrphostin AG-1478 hydrochloride) is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 hydrochloride has antiviral effects against HCV and encephalomyocarditis virus (EMCV). |
| CSN22160 | ACH-806 | 870142-71-5 | ACH-806 is an NS4A antagonist which can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM. |
| CSN23603 | 4-Phenoxybenzylamine | 107622-80-0 | 4-Phenoxybenzylamine can stabilize the NS3 protein in an inactive state with IC50 of 500 μM. |
| CSN60078 | Bemnifosbuvir | 1998705-64-8 | |
| CSN61906 | Ledipasvir-d6 | 2050041-12-6 | |
| CSN51384 | Bersacapavir | 1638266-40-6 | |
| CSN51411 | BMS-986144 | 1606150-08-6 | |
| CSN51417 | GSK2818713 | 1422484-32-9 |
