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HDAC

HDAC

货号 产品名 CAS号 信息
CSN17250 UF010 537672-41-6 UF010 is a selective inhibitor of HDAC3, 2, 1 and 8 with IC50s of 0.06 μM, 0.1 μM, 0.5 μM and 1.5 μM, respectively.
CSN19743 Sulforaphane Racemate 4478-93-7 Sulforaphane, a natural product isolated and purified from the seeds of Brassica oleracea L. var. botrytis L. with neuroprotective, anti-inflammatory and antitumor effects, inhibits TPA-induced NF-κB activation and COX-2 expression in MCF-10A cells by blocking two distinct signaling pathways mediated by ERK1/2-IKKα and NAK-IKKβ.
CSN21182 SR-4370 1816294-67-3 SR-4370 is an inhibitor of HDAC, with IC50s of 0.13 μM, 0.58 μM, 0.006 μM, 2.3 μM, and 3.4 μM for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively.
CSN24467 SIS17 2374313-54-7 SIS17 is a specific HDAC11 inhibitor with IC50 value of 0.83μM for inhibition of the demyristoylation HDAC11 substrate, serine hydroxymethyl transferase 2.
CSN18796 RGFP966 Racemate 1396841-57-8 RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM in cell-free assay, exhibits > 200-fold selectivity over other HDAC.
CSN17367 RG2833 1215493-56-3 RG2833 is a brain-penetrant HDAC inhibitor with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3, respectively.
CSN17824 LMK-235 1418033-25-6 LMK235 is a HDAC inhibitor of human HDAC4 and HDAC5 with IC50 values of 0.49 μM (A2780) and 0.32 μM (A2780 CisR).
CSN18800 HPOB 1429651-50-2 HPOB is a selective inhibitor of HDAC6 with IC50 of 56 nM.
CSN18083 Givinostat HCl 199657-29-9 Givinostat HCl is a potent HDAC inhibitor for Maize HD2, HD1-B and HD1-A with IC50 of 10 nM, 7.5 nM and 16 nM, respectively.
CSN18647 Droxinostat 99873-43-5 Droxinostat is an inhibitor of HDAC3, HDAC6, and HDAC8 with IC50 of 16.9, 2.47 and 1.46 μM, respectively.
CSN17366 BRD73954 1440209-96-0 BRD73954 is a selective inhibitor of HDAC6 and HDAC8 with IC50 of 36 nM and 120 nM, respectively.
CSN20569 BRD3308 1550053-02-5 BRD3308 is a highly selective inhibitor of histone deacetylase 3 (HDAC3) with an IC50 value of 65 nM for HDAC3 vs.
CSN22724 BRD 4354 315698-07-8 BRD 4354 is an inhibitor of HDAC5 and HDAC9 with IC50s of 0.85 and 1.88 μM respectively.
CSN21754 Biphenyl-4-sulfonyl Chloride 1623-93-4 Biphenyl-4-sulfonyl chloride is an inhibitor of HDAC and it has synthetic applications in palladium-catalyzed desulfitative C-arylation.
CSN17264 BG45 926259-99-6 BG45 is a selective inhibitor for HDAC3 with IC50 of 289 nM.
CSN17336 Belinostat 866323-14-0 Belinostat is a pan-HDAC inhibitor with IC50 of 27 nM, with activity demonstrated in cisplatin-resistant tumors.
CSN27278 ACY-775   1375466-18-4 ACY-775 is a potent and selective inhibitor of the of histone deacetylase 6 (HDAC6) with an IC50 of 7.5 nM.
CSN23643 4-Phenylbutanoic acid 1821-12-1 4-Phenylbutanoic acid is an inhibitor of HDAC which can regulate gene transcription with anti-tumor and neuroprotective effects.
CSN19518 4-Hydroxybenzoic Acid 99-96-7 4-Hydroxybenzoic acid, a natural product isolated and purified from the herbs of Rhodiola crenulata, positively regulates the expression of gum cluster to promote EPS production in PXO99A, and its derivatives have potential to as pan-HDAC inhibitors with anticancer properties.
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