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HDAC
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN17250 | UF010 | 537672-41-6 | UF010 is a selective inhibitor of HDAC3, 2, 1 and 8 with IC50s of 0.06 μM, 0.1 μM, 0.5 μM and 1.5 μM, respectively. |
| CSN19743 | Sulforaphane Racemate | 4478-93-7 | Sulforaphane, a natural product isolated and purified from the seeds of Brassica oleracea L. var. botrytis L. with neuroprotective, anti-inflammatory and antitumor effects, inhibits TPA-induced NF-κB activation and COX-2 expression in MCF-10A cells by blocking two distinct signaling pathways mediated by ERK1/2-IKKα and NAK-IKKβ. |
| CSN21182 | SR-4370 | 1816294-67-3 | SR-4370 is an inhibitor of HDAC, with IC50s of 0.13 μM, 0.58 μM, 0.006 μM, 2.3 μM, and 3.4 μM for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively. |
| CSN24467 | SIS17 | 2374313-54-7 | SIS17 is a specific HDAC11 inhibitor with IC50 value of 0.83μM for inhibition of the demyristoylation HDAC11 substrate, serine hydroxymethyl transferase 2. |
| CSN18796 | RGFP966 Racemate | 1396841-57-8 | RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM in cell-free assay, exhibits > 200-fold selectivity over other HDAC. |
| CSN17367 | RG2833 | 1215493-56-3 | RG2833 is a brain-penetrant HDAC inhibitor with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3, respectively. |
| CSN17824 | LMK-235 | 1418033-25-6 | LMK235 is a HDAC inhibitor of human HDAC4 and HDAC5 with IC50 values of 0.49 μM (A2780) and 0.32 μM (A2780 CisR). |
| CSN18800 | HPOB | 1429651-50-2 | HPOB is a selective inhibitor of HDAC6 with IC50 of 56 nM. |
| CSN18083 | Givinostat HCl | 199657-29-9 | Givinostat HCl is a potent HDAC inhibitor for Maize HD2, HD1-B and HD1-A with IC50 of 10 nM, 7.5 nM and 16 nM, respectively. |
| CSN18647 | Droxinostat | 99873-43-5 | Droxinostat is an inhibitor of HDAC3, HDAC6, and HDAC8 with IC50 of 16.9, 2.47 and 1.46 μM, respectively. |
| CSN17366 | BRD73954 | 1440209-96-0 | BRD73954 is a selective inhibitor of HDAC6 and HDAC8 with IC50 of 36 nM and 120 nM, respectively. |
| CSN20569 | BRD3308 | 1550053-02-5 | BRD3308 is a highly selective inhibitor of histone deacetylase 3 (HDAC3) with an IC50 value of 65 nM for HDAC3 vs. |
| CSN22724 | BRD 4354 | 315698-07-8 | BRD 4354 is an inhibitor of HDAC5 and HDAC9 with IC50s of 0.85 and 1.88 μM respectively. |
| CSN21754 | Biphenyl-4-sulfonyl Chloride | 1623-93-4 | Biphenyl-4-sulfonyl chloride is an inhibitor of HDAC and it has synthetic applications in palladium-catalyzed desulfitative C-arylation. |
| CSN17264 | BG45 | 926259-99-6 | BG45 is a selective inhibitor for HDAC3 with IC50 of 289 nM. |
| CSN17336 | Belinostat | 866323-14-0 | Belinostat is a pan-HDAC inhibitor with IC50 of 27 nM, with activity demonstrated in cisplatin-resistant tumors. |
| CSN27278 | ACY-775 | 1375466-18-4 | ACY-775 is a potent and selective inhibitor of the of histone deacetylase 6 (HDAC6) with an IC50 of 7.5 nM. |
| CSN23643 | 4-Phenylbutanoic acid | 1821-12-1 | 4-Phenylbutanoic acid is an inhibitor of HDAC which can regulate gene transcription with anti-tumor and neuroprotective effects. |
| CSN19518 | 4-Hydroxybenzoic Acid | 99-96-7 | 4-Hydroxybenzoic acid, a natural product isolated and purified from the herbs of Rhodiola crenulata, positively regulates the expression of gum cluster to promote EPS production in PXO99A, and its derivatives have potential to as pan-HDAC inhibitors with anticancer properties. |