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HDAC
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN11991 | N1-Hydroxy-N8-phenyloctanediamide | 149647-78-9 | Vorinostat is an HDAC1/3 inhibitor with IC50 of ~10 nM. |
CSN12139 | Trichostatin A | 58880-19-6 | Trichostatin A is a selective and potent HDAC inhibitor with IC50 of ~1.8 nM and HDAC8 is the only known member of the HDAC-family that is not affected by TSA. |
CSN11945 | Sodium Butyrate | 156-54-7 | Sodium butyrate is a histone deacetylase (HDAC) inhibitor with IC50s are 0.3 mM, 0.4 mM, 0.3 mM for HDAC1, 2 and 7 respectively. |
CSN11942 | Sodium 4-phenylbutanoate | 1716-12-7 | Sodium 4-phenylbutyrate is an inhibitor of histone deacetylase that has been used to treat urea cycle disorders. |
CSN10407 | (1H-Benzo[d][1,2,3]triazol-1-yl)(2,4-dichlorophenyl)methanone | 200626-61-5 | ITSA-1 is activator of HDAC by suppressing TSA. |
CSN18936 | Zabadinostat | 934828-12-3 | HDAC-IN-4 is a histone deacetylase (HDAC) inhibitor. |
CSN11480 | Pyridin-3-ylmethyl 4-((2-aminophenyl)carbamoyl)benzylcarbamate | 209783-80-2 | Entinostat strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM. |
CSN20355 | Tinostamustine | 1236199-60-2 | EDO-S101 is a pan HDAC inhibitor and inhibits HDAC1, HDAC2 and HDAC3 with IC50 values of 9, 9 and 25 nM, respectively. |
CSN11550 | N-Hydroxy-3-(3-(N-phenylsulfamoyl)phenyl)acrylamide | 414864-00-9 | Belinostat is a HDAC inhibitor with IC50 of 27 nM in a cell-free assay, with activity demonstrated in cisplatin-resistant tumors. |
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