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HDAC

HDAC

货号 产品名 CAS号 信息
CSN11991 N1-Hydroxy-N8-phenyloctanediamide   149647-78-9 Vorinostat is an HDAC1/3 inhibitor with IC50 of ~10 nM.
CSN12139 Trichostatin A 58880-19-6 Trichostatin A is a selective and potent HDAC inhibitor with IC50 of ~1.8 nM and HDAC8 is the only known member of the HDAC-family that is not affected by TSA.
CSN11945 Sodium Butyrate 156-54-7 Sodium butyrate is a histone deacetylase (HDAC) inhibitor with IC50s are 0.3 mM, 0.4 mM, 0.3 mM for HDAC1, 2 and 7 respectively.
CSN11942 Sodium 4-phenylbutanoate 1716-12-7 Sodium 4-phenylbutyrate is an inhibitor of histone deacetylase that has been used to treat urea cycle disorders.
CSN10407 (1H-Benzo[d][1,2,3]triazol-1-yl)(2,4-dichlorophenyl)methanone 200626-61-5 ITSA-1 is activator of HDAC by suppressing TSA.
CSN18936 Zabadinostat 934828-12-3 HDAC-IN-4 is a histone deacetylase (HDAC) inhibitor.
CSN11480 Pyridin-3-ylmethyl 4-((2-aminophenyl)carbamoyl)benzylcarbamate   209783-80-2 Entinostat strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM.
CSN20355 Tinostamustine 1236199-60-2 EDO-S101 is a pan HDAC inhibitor and inhibits HDAC1, HDAC2 and HDAC3 with IC50 values of 9, 9 and 25 nM, respectively.
CSN11550 N-Hydroxy-3-(3-(N-phenylsulfamoyl)phenyl)acrylamide 414864-00-9 Belinostat is a HDAC inhibitor with IC50 of 27 nM in a cell-free assay, with activity demonstrated in cisplatin-resistant tumors.
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