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Hedgehog
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN18358 | Veratramine | 60-70-8 | Veratramine is a natually occuring alkaloid isolated from the rhizomes of Veratrum and can inhibit the Hh signaling-dependent proliferation of NIH/3T3 cells for it is an analog of cyclopamine. |
CSN17420 | RU-SKI 43 | 1043797-53-0 | RU-SKI 43 is a small molecule inhibitor of Hhat (Hedgehog acyltransferase), the enzyme responsible for the attachment of palmitate onto Shh. |
CSN10046 | Mebendazole | 31431-39-7 | Mebendazole is an inhibitor of hedgehog and a broad spectrum antihelmintic for the treatment of nematode infestations. |
CSN13124 | JK184 | 315703-52-7 | JK184 is a hedgehog (Hh) pathway inhibitor with IC50 of 30 nM in mammalian cells. |
CSN19162 | Ciliobrevin A | 302803-72-1 | Ciliobrevin A inhibits hedgehog (Hh) signaling pathway with IC50 less than 10 μM. |
CSN22696 | AY 9944 2HCl | 366-93-8 | AY 9944 2HCl is an inhibitor of hedgehog (Hh) signaling. |
CSN25227 | 20(S)-Hydroxycholesterol | 516-72-3 | 20(S)-Hydroxycholesterol is an allosteric activator of the Hedgehog signaling pathway Smoothened (Smo) oncoprotein. It activates Hedgehog (Hh) signaling with EC50 value of ~ 3μM for induction of Hh reporter gene transcription in NIH 3T3 cells. |
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