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Histamine Receptor

Histamine Receptor

货号 产品名 CAS号 信息
CSN25848 Zolantidine dimaleate 104076-39-3 Zolantidine dimaleate is a selective and brain penetrating H2 receptor antagonist.
CSN25862 VUF 8430 dihydrobromide 100130-32-3 VUF 8430 dihydrobromide is a full agonist of histamine H4 receptor with pKi of 7.5 and pEC50 of 7.3.
CSN21874 Tritoqualine 14504-73-5 Tritoqualine is a histamine H1 antagonist.
CSN21872 Triprolidine HCl 6138-79-0 Triprolidine Hydrochloride is the first generation histamine H1 antagonist used in allergic rhinitis.
CSN25841 Trans-Triprolidine HCl 550-70-9 Trans-Triprolidine hydrochloride is a potent H1 receptor antagonist.
CSN25844 Tiotidine 69014-14-8 Tiotidine is antagonist of histamine H2-receptor with negligible activity against H1- and H3- receptors.
CSN26513 SUN-1334H (HCl) 607736-84-5 SUN-1334H is a histamine H1 receptor antagonist potentially for the treatment of allergic conjunctivitis and allergic rhinitis
CSN21826 Rocastine 91833-77-1 Rocastine is a selective antagonist of nonsedative H1 antagonist for antihistamines.
CSN26180 PU-02   313984-77-9 PU-02 is an antagonist of serotonin (5-HT) receptor subtype 5-HT3.
CSN17113 Promethazine HCl 58-33-3 Promethazine HCl is the effective antagonist of the H1 receptor and moderate antagonist of mACh receptor.
CSN25855 Nα-Methylhistamine 2HCl 16503-22-3 Nα-Methylhistamine dihydrochloride is H2R agonist that acts directly on histamine H(2) receptors (H2Rs) in animals to stimulate acid secretion and it dose dependently stimulated cAMP productions in CHO-H2R cells.
CSN11591 Nylidrin HCl 849-55-8 Nylidrin HCl was an effective inhibitor of IgE-mediated release of histamine from passively sensitized rat peritoneal mast cells and human basophils, and of IgG1-mediated release of histamine from passively sensitized guinea pig lung slices.
CSN21744 Niperotidine 84845-75-0 Niperotidine is an antagonist of histamine H2-receptor.
CSN11531 Nedocromil 69049-73-6 Nedocromil is an inhaled anti-inflammatory agent for the preventive management of asthma.
CSN14575 Marmin 14957-38-1 Marmin, a natural product isolated and purified from the herbs of Citrus maxima with potent anti-ulcer, antibacterial, fungicidal, and algicidal properties, can inhibit contraction of the guinea-pig tracheal smooth muscle, especially by interfering histamine receptor, inhibiting the histamine release from mast, inhibiting intracellular Ca2+ release from the intracellular store and the Ca2+ influx through voltage-dependent Ca2+ channels, is potential to develop as antihistamine agents, especially as histamine H1 receptor antagonists by interacting with amino acid residues, Asp107, Lys179, Lys191, Asn198, and Trp428 of histamine H1 receptor, shows a cell-growth inhibitory effect against L1210 and K562 in vitro.
CSN25854 Iodophenpropit dihydrobromide 145196-87-8 Iodophenpropit dihydrobromide is an antagonist of H3 recetor with high affinity (Kd = 0.3 nM).
CSN25851 Impentamine dihydrobromide 149629-70-9 Impentamine dihydrobromide is highly selective antagonist of histamine H3 receptor with pA2 of 8.4.
CSN25847 Ici162,846 84545-30-2 ICI 162,846 is a potent histamine H2 receptor antagonist.
CSN25852 GT 2016 152241-24-2 GT 2016 is a high affinity antagonist of H3 receptor with Ki of 43.8 nM.
CSN22023 FRG8701 108498-50-6 FRG-8701 is a new Histamine H2-receptor antagonist with IC50 of ranging from 0.25 to 0.43 μM.
CSN21734 FPL59360 85118-44-1 FPL59360, a anti-asthmatic compound, is histamine I receptor antagonist that prevents exercise-induced asthma.
CSN24500 Emedastine 87233-61-2 Emedastine is a potent, high affinity histamine H1-receptor-selective antagonist with Ki of 1.3 ±0.1 nM for H1-receptors while considerably weaker at H2- (Ki = 49,067 ± 11,113 nM) and H3-receptors (Ki = 12,430 ± 1,282 nM).
CSN25845 Dimaprit 2HCl 23256-33-9 Dimaprit dihydrochloride is a selective H2 agonist with central effects upon systemic administration.
CSN22573 Cyclizine 2HCl 5897-18-7 Cyclizine is a histamine H1 receptor antagonist of the piperazine class.
CSN22139 Cipralisant 213027-19-1 Cipralisant is a potent and selective histamine H3 receptor antagonist in vivo, and an agonist in vitro, with a pKi of 9.9 for histamine H3 receptor and a Ki of 0.47 nM for rat histamine H3 receptor; Cipralisant has entered in clinical trials for the treatment of attention-deficit hyperactivity disorder.
CSN26664 Cimetidine sulfoxide 54237-72-8 Cimetidine sulfoxide (Cimetidine sulphoxide) is a sulfoxide metabolite of Cimetidine. Cimetidine is a histamine H2-receptor antagonist. Cimetidine has the potential for peptic ulcer disease and upper gastrointestinal haemorrhage treatment[1].
CSN26201 Chloropyramine HCl 6170-42-9 Chloropyramine hydrochloride is a histamine receptor H1 antagonist which can also inhibit the biochemical function of VEGFR-3. Chloropyramine hydrochloride may be useful in the treatment of invasive breast cancer.
CSN25269 Bromazine HCl 1808-12-4 Bromazine hydrochloride is an antagonist of histamine H1 receptor.
CSN22167 BMY-25271 78441-82-4 BMY-25271 is a histamine H2 receptor antagonist.
CSN25225 Betahistine 5638-76-6 Betahistine is a histamine analog and H1 receptor agonist.
CSN24137 Bepotastine 125602-71-3 Bepotastine is a non-sedating and selective antagonist of the histamine 1 (H1) receptor.
CSN24556 AR-R 17779 hydrochloride 178419-42-6 AR-R 17779 hydrochloride is a selective alpha7 nicotinic agonist with Ki value of 190 nM for rat.
CSN22242 Antihistamine-1 1186430-60-3 Antihistamine-1 is a H1-antihistamine (Ki=6.9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel with IC50s of 5.4 and 0.8 μM, respectively.
CSN25846 Amthamine dihydrobromide 142457-00-9 Amthamine dihydrobromide is a highly selective agonist of H2 receptor.
CSN25843 Aminopotentidine 140873-26-3 Aminopotentidine is antagonist of H2 with KB value of 220 nM.
CSN21455 Acrivastine 87848-99-5 Acrivastine, an H1-receptor antagonist, is a second-generation antihistamine.
CSN23462 5-Hydroxyindole-3-acetic acid 54-16-0 5-Hydroxyindole-3-acetic acid (5-HIAA), the major metabolite of serotonin, is a histamine H1 receptor antagonist and can be used to treat allergies.
CSN25863 4-Methylhistamine 2HCl 36376-47-3 4-Methylhistamine dihydrochloride is a high affinity agonist of H4 receptor with Ki of 7 nM.
CSN25840 2-(Pyridin-2-yl)ethanamine dihydrochloride 3343-39-3 2-Pyridylethylamine dihydrochloride is an agonist of histamine H1 receptor that produces vasoconstriction.
CSN21849 Tazifylline 79712-55-3 (±)-Tazifylline is a selective and long-acting antagonist of histamine H1 receptor.
CSN24562 (S)-(+)-Dimethindene maleate 136152-65-3 (S)-(+)-Dimethindene maleate is a subtype-selective M2 muscarinic receptor antagonist with pKi of 7.78 and is also a H1 histamine receptor antagonist with pKi of 7.48.
CSN25856 (R)-(-)-α-Methylhistamine 2HBr 868698-49-1 (R)-(-)-α-Methylhistamine dihydrobromide is a very potent agonist of H3 receptor with Kd of 50.3 nM that crosses the blood-brain barrier and inhibits histamine synthesis and release at nanomolar concentrations.
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