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HSP
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN20344 | TRC051384 HCl | 1333327-56-2 | TRC051384 is an inducer of heat shock protein Hsp70. it reduces stroke-associated neuronal injury and increases survival in a rat model of transient ischemic stroke and activates heat shock factor-1 and results in elevated chaperone and anti-inflammatory activity. |
| CSN20345 | TRC051384 | 867164-40-7 | TRC051384 is a inducer of Hsp70. |
| CSN18482 | Retaspimycin HCl | 857402-63-2 | Retaspimycin HCl is the HCl salt of a small-molecule inhibitor of heat shock protein 90 (HSP90) with antiproliferative and antineoplastic activities. |
| CSN15760 | PU-WS13 | 1454619-14-7 | PU-WS13 is a potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class. |
| CSN16046 | PU-H 71 | 873436-91-0 | PU-H71 is a potent Hsp90 inhibitor with IC50 of 50 nM. |
| CSN17514 | PF-04929113 Mesylate | 1173111-67-5 | PF-04929113 mesylate is a potent and selective Hsp90 inhibitor with an IC50 of median 50 nM. |
| CSN26243 | Nonactin | 6833-84-7 | Nonactin is a cyclic ionophore and part of the macrotetrolide antibiotics family that selectively binds K+ and NH4+. When exposed to erythrocytes, it causes erythrocyte shrinkage and subsequent erythrocyte membrane scrambling. |
| CSN17387 | ML346 | 100872-83-1 | ML346 is an activator of Hsp70 with EC50 of 4600 nM in HeLa cell toxicity assay. |
| CSN21425 | MKT-077 | 147366-41-4 | MKT-077 (FJ-776) is a water-soluble rhodacyanine dye with antitumor activity. It can bind to Hsp70 family member mortalin-2 and inhibit its interactions with p53. |
| CSN18942 | KRIBB11 | 342639-96-7 | KRIBB11 is an inhibitor of heat shock factor (HSF) inhibitor, with IC50 of 1.2 μM. |
| CSN17321 | KNK437 | 218924-25-5 | KNK437 is a pan-HSP inhibitor, which inhibits the synthesis of inducible HSPs, including HSP105, HSP72, and HSP40. |
| CSN22828 | Gedunin | 2753-30-2 | Gedunin is a Hsp90 inhibitor and exhibits anticancer and antimalarial activity. |
| CSN13554 | Eupalinolide B | 877822-41-8 | Eupalinolide A is a natural product isolated and purified from the herbs of Eupatorium lindleyanum DC. |
| CSN25416 | Ethoxyquin | 91-53-2 | Ethoxyquin is an antioxidant which has been used in animal feed for many years and also an inhibitor of heat shock protein 90 (Hsp90). |
| CSN22743 | CCT 018159 | 171009-07-7 | CCT 018159 is a novel inhibitor of heat shock protein 90 (Hsp90) ATPase activity with IC50 of 5.7 μM. |
| CSN26679 | 5'-Adenylyl methylenediphosphonate | 3469-78-1 | AMP-PCP is an ATP analogue and can bind to Hsp90 N-terminal domain with a Kd value of 3.8 μM. AMP-PCP binding favors the formation of the active homodimer of Hsp90[1]. |
| CSN17209 | 17-AAG | 75747-14-7 | 17-AAG is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. |
