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HSP

HSP

货号 产品名 CAS号 信息
CSN20344 TRC051384 HCl 1333327-56-2 TRC051384 is an inducer of heat shock protein Hsp70. it reduces stroke-associated neuronal injury and increases survival in a rat model of transient ischemic stroke and activates heat shock factor-1 and results in elevated chaperone and anti-inflammatory activity.
CSN20345 TRC051384 867164-40-7 TRC051384 is a inducer of Hsp70.
CSN18482 Retaspimycin HCl 857402-63-2 Retaspimycin HCl is the HCl salt of a small-molecule inhibitor of heat shock protein 90 (HSP90) with antiproliferative and antineoplastic activities.
CSN16046 PU-H 71 873436-91-0 PU-H71 is a potent Hsp90 inhibitor with IC50 of 50 nM.
CSN17514 PF-04929113 Mesylate 1173111-67-5 PF-04929113 mesylate is a potent and selective Hsp90 inhibitor with an IC50 of median 50 nM.
CSN32496 PEN-866 1472614-83-7 PEN-866 is a novel esterase-cleavable conjugate of an HSP90i and a topoisomerase I inhibitor.
CSN12794 Palmitic Acid 57-10-3 Palmitic acid, a natural product isolated and purified from the herbs of Atractylodes macrocephala Koidz., induces down-regulation of APOM expression and anxiety-like behavior in mice while increasing amygdala-based serotonin metabolism. Palmitic acid has a significant impact on proliferation and differentiation of NSCs in vitro and may be useful for elucidating the role of SFAs in regulating NSCs fate in physiological and pathological settings.Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells.
CSN26243 Nonactin 6833-84-7 Nonactin is a cyclic ionophore and part of the macrotetrolide antibiotics family that selectively binds K+ and NH4+. When exposed to erythrocytes, it causes erythrocyte shrinkage and subsequent erythrocyte membrane scrambling.
CSN17387 ML346 100872-83-1 ML346 is an activator of Hsp70 with EC50 of 4600 nM in HeLa cell toxicity assay.
CSN21425 MKT-077 147366-41-4 MKT-077 (FJ-776) is a water-soluble rhodacyanine dye with antitumor activity. It can bind to Hsp70 family member mortalin-2 and inhibit its interactions with p53.
CSN18942 KRIBB11 342639-96-7 KRIBB11 is an inhibitor of heat shock factor (HSF) inhibitor, with IC50 of 1.2 μM.
CSN17321 KNK437 218924-25-5 KNK437 is a pan-HSP inhibitor, which inhibits the synthesis of inducible HSPs, including HSP105, HSP72, and HSP40.
CSN22828 Gedunin 2753-30-2 Gedunin is a Hsp90 inhibitor and exhibits anticancer and antimalarial activity.
CSN13554 Eupalinolide B 877822-41-8 Eupalinolide A is a natural product isolated and purified from the herbs of Eupatorium lindleyanum DC.
CSN25416 Ethoxyquin 91-53-2 Ethoxyquin is an antioxidant which has been used in animal feed for many years and also an inhibitor of heat shock protein 90 (Hsp90).
CSN26679 5'-Adenylyl methylenediphosphonate 3469-78-1 AMP-PCP is an ATP analogue and can bind to Hsp90 N-terminal domain with a Kd value of 3.8 μM. AMP-PCP binding favors the formation of the active homodimer of Hsp90[1].
CSN17209 17-AAG 75747-14-7 17-AAG is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells.
CSN28855 3-(4-Fluorophenyl)chroman-4-one 1143863-69-7
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