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HSP

HSP

货号 产品名 CAS号 信息
CSN20344 TRC051384 HCl 1333327-56-2 TRC051384 is an inducer of heat shock protein Hsp70. it reduces stroke-associated neuronal injury and increases survival in a rat model of transient ischemic stroke and activates heat shock factor-1 and results in elevated chaperone and anti-inflammatory activity.
CSN20345 TRC051384 867164-40-7 TRC051384 is a inducer of Hsp70.
CSN18482 Retaspimycin HCl 857402-63-2 Retaspimycin HCl is the HCl salt of a small-molecule inhibitor of heat shock protein 90 (HSP90) with antiproliferative and antineoplastic activities.
CSN15760 PU-WS13 1454619-14-7 PU-WS13 is a potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class.
CSN16046 PU-H 71 873436-91-0 PU-H71 is a potent Hsp90 inhibitor with IC50 of 50 nM.
CSN17514 PF-04929113 Mesylate 1173111-67-5 PF-04929113 mesylate is a potent and selective Hsp90 inhibitor with an IC50 of median 50 nM.
CSN26243 Nonactin 6833-84-7 Nonactin is a cyclic ionophore and part of the macrotetrolide antibiotics family that selectively binds K+ and NH4+. When exposed to erythrocytes, it causes erythrocyte shrinkage and subsequent erythrocyte membrane scrambling.
CSN17387 ML346 100872-83-1 ML346 is an activator of Hsp70 with EC50 of 4600 nM in HeLa cell toxicity assay.
CSN21425 MKT-077 147366-41-4 MKT-077 (FJ-776) is a water-soluble rhodacyanine dye with antitumor activity. It can bind to Hsp70 family member mortalin-2 and inhibit its interactions with p53.
CSN18942 KRIBB11 342639-96-7 KRIBB11 is an inhibitor of heat shock factor (HSF) inhibitor, with IC50 of 1.2 μM.
CSN17321 KNK437 218924-25-5 KNK437 is a pan-HSP inhibitor, which inhibits the synthesis of inducible HSPs, including HSP105, HSP72, and HSP40.
CSN22828 Gedunin 2753-30-2 Gedunin is a Hsp90 inhibitor and exhibits anticancer and antimalarial activity.
CSN13554 Eupalinolide B 877822-41-8 Eupalinolide A is a natural product isolated and purified from the herbs of Eupatorium lindleyanum DC.
CSN25416 Ethoxyquin 91-53-2 Ethoxyquin is an antioxidant which has been used in animal feed for many years and also an inhibitor of heat shock protein 90 (Hsp90).
CSN22743 CCT 018159 171009-07-7 CCT 018159 is a novel inhibitor of heat shock protein 90 (Hsp90) ATPase activity with IC50 of 5.7 μM.
CSN26679 5'-Adenylyl methylenediphosphonate 3469-78-1 AMP-PCP is an ATP analogue and can bind to Hsp90 N-terminal domain with a Kd value of 3.8 μM. AMP-PCP binding favors the formation of the active homodimer of Hsp90[1].
CSN17209 17-AAG 75747-14-7 17-AAG is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells.
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