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HSP

HSP

货号 产品名 CAS号 信息
CSN13116 VER-155008 1134156-31-2 VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively, > 100-fold selectivity over HSP90.
CSN20344 TRC051384 HCl 1333327-56-2 TRC051384 is an inducer of heat shock protein Hsp70. it reduces stroke-associated neuronal injury and increases survival in a rat model of transient ischemic stroke and activates heat shock factor-1 and results in elevated chaperone and anti-inflammatory activity.
CSN12051 Teprenone 6809-52-5 Teprenone is used as an anti-ulcer drug, a cardioprotective agent, a hepatoprotective agent, a nephroprotective agent, a neuroprotective agent and a Hsp70 inducer.
CSN22232 TAS-116 1260533-36-5 TAS-116 is a potent and selective HSP90α/β inhibitor with Kis of 34.7 nM, 21.3 nM, respectively.
CSN15760 PU-WS13 1454619-14-7 PU-WS13 is a potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class.
CSN16046 PU-H 71 873436-91-0 PU-H71 is a potent Hsp90 inhibitor with IC50 of 50 nM.
CSN17514 PF-04929113 Mesylate 1173111-67-5 PF-04929113 mesylate is a potent and selective Hsp90 inhibitor with an IC50 of median 50 nM.
CSN17387 ML346 100872-83-1 ML346 is an activator of Hsp70 with EC50 of 4600 nM in HeLa cell toxicity assay.
CSN21425 MKT-077 147366-41-4 MKT-077 (FJ-776) is a water-soluble rhodacyanine dye with antitumor activity. It can bind to Hsp70 family member mortalin-2 and inhibit its interactions with p53.
CSN18942 KRIBB11 342639-96-7 KRIBB11 is an inhibitor of heat shock factor (HSF) inhibitor, with IC50 of 1.2 μM.
CSN17321 KNK437 218924-25-5 KNK437 is a pan-HSP inhibitor, which inhibits the synthesis of inducible HSPs, including HSP105, HSP72, and HSP40.
CSN11085 Geldanamycin 30562-34-6 Geldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 μM.
CSN22828 Gedunin 2753-30-2 Gedunin is a Hsp90 inhibitor and exhibits anticancer and antimalarial activity.
CSN25416 Ethoxyquin 91-53-2 Ethoxyquin is an antioxidant which has been used in animal feed for many years and also an inhibitor of heat shock protein 90 (Hsp90).
CSN27185 Col003   328565-16-8 Col003 is a cell penetrant, selective and potent inhibitor of the interaction of Hsp47 with collagen. Col003 is the cleavage product of AK778.It competitively inhibited the interaction and caused the inhibition of collagen secretion by destabilizing the collagen triple helix.
CSN18941 Apoptozole 1054543-47-3 Apoptozole is an inhibitor of heat shock protein 70 (HSP70) and Hsc70. It induces caspase-dependent apoptosis.
CSN17209 17-AAG 75747-14-7 17-AAG is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells.
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