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IDO
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN16276 | PF-06840003 | 198474-05-4 | PF-06840003 is a highly selective orally bioavailable IDO-1 inhibitor with IC50 of 0.41 μM. |
| CSN13930 | IDO-IN-7 | 1402836-58-1 | NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM in cell-free assays. |
| CSN15702 | Indoximod | 110117-83-4 | Indoximod is an indoleamine 2,3-dioxygenase (IDO) pathway inhibitor with a Ki of 19 μM. |
| CSN15728 | IDO5L | 914471-09-3 | INCB024360 analogue is a potent, competitive IDO1 (indoleamine-(2,3)-dioxygenase) inhibitor with IC50 of 67 nM. |
| CSN17798 | IDO-IN-8 | 1402837-77-7 | IDO-IN-8 is a potent human IDO inhibitor with IC50 of 1-10 μM. |
| CSN17799 | Navoximod | 1402837-78-8 | IDO-IN-7 is a potent human IDO inhibitor with IC50 of < 1 μM. |
| CSN17797 | IDO-IN-6 | 1402837-76-6 | IDO-IN-6 is a potent human IDO inhibitor with IC50 of < 1 μM. |
| CSN17800 | IDO-IN-5 | 1402837-79-9 | IDO-IN-5 is a potent human IDO inhibitor with IC50 of 1-10 μM. |
| CSN17969 | BMS-978587 | 1629125-65-0 | IDO-IN-4 is a potent IDO1 inhibitor with IC50 of 8 nM in human IDO1/HEK293 cells. |
| CSN19054 | IDO-IN-3 | 2070018-30-1 | IDO-IN-3 is a potent IDO inhibitor. |
| CSN19043 | PCC0208009 | 1668565-74-9 | IDO-IN-2 is an IDO inhibitor with IC50 value of 68 nM and 160 nM in HeLa cell and HEK293 cell, respectively. |
| CSN16919 | IDO-IN-1 | 914638-30-5 | IDO-IN-1 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50 of 59 nM, shows activity in Hela cell (IC50=12 nM). |
| CSN25219 | IDO-IN-13 | 2291164-02-6 | GS-4361 is an IDO1 inhibitor. |
| CSN13892 | Epacadostat | 1204669-58-8 | Epacadostat is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM and displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). |
| CSN20317 | Linrodostat | 1923833-60-6 | BMS-986205 is a specific and irreversible inhibitor of IDO1 with IC50 value of 1.7 nM. |
| CSN19041 | GNF-PF-3777 | 77603-42-0 | 8-Nitrotryptanthrin is a potent human indoleamine 2,3-dioxygenase 2 (hIDO2) inhibitor which significantly reduces IDO2 activity with Ki of 0.97 μM. |
| CSN51377 | IDO1-IN-11 | 2306411-34-5 |
