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Inflammation/Immunology

货号 产品名 CAS号 信息
CSN22353 AZ3451 2100284-59-9 AZ3451 is a protease-activated receptor-2 (PAR2) antagonist.
CSN22493 Pumaprazole 158364-59-1 Pumaprazole is a reversible proton pump antagonist.
CSN22357 Beperidium Iodide 86434-57-3 Beperidium iodide shows a competitive antagonistic effect against acetylcholine receptor with a pA2 of 7.93.
CSN22337 Adavivint 1467093-03-3 Adavivint is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells.
CSN22322 (-)-Ketoconazole 142128-57-2 (-)-Ketoconazole is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers, levoketoconazole ((2S,4R)-(−)-ketoconazole) and dextroketoconazole ((2R,4S)-(+)-ketoconazole).
CSN22471 Nedocromil Sodium 69049-74-7 Nedocromil Sodium is a potent TNF-α inhibitor with an IC50 value of 1.67 μM for Blood eosinophils.
CSN22402 Fodipir 118248-91-2 Fodipir is an active metabolite of mangafodipir, involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death.
CSN22454 Lymecycline 992-21-2 Lymecycline is a tetracycline derivative, with broad-spectrum antibacterial activity and also has anti-inflammatory property.
CSN22371 Cephalosporin C Zinc Salt 59143-60-1 Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC50 of 1.1 μM.
CSN22191 MK-0429 227963-15-7 MK-0429 is a potent integrin antagonist with IC50s of 12.2 nM (α5β1 integrin) and 2.8 nM (αvβ3 integrin), respectively.
CSN22204 Bimosiamose 187269-40-5 Bimosiamose is a pan-selectin antagonist, inhibits E-, P-, and L-selectin with IC50s of 88 μM, 20 μM, and 86 μM, respectively, and can be used in the research of inflammatory disease.
CSN22375 Cl-amidine 913723-61-2 Cl-amidine is a peptidylarginine deminase (PAD) inhibitor, with an IC50 5.9±0.3 μM for PAD4.
CSN22333 A-69412 123606-23-5 A-69412 is a reversible, specific inhibitor of the hydrophilic 5-lipoxygenase (5-LO).
CSN22433 Iralukast 151581-24-7 Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.
CSN22409 Gefapixant 1015787-98-0 Gefapixant is an orally active P2X3 receptor (P2X3R) antagonist with IC50s of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.
CSN22527 TY-51469 603987-59-3 TY-51469 is a chymase inhibitor with IC50s for simian and human chymases of 0.4 and 7.0 nM, respectively.
CSN22535 YM-264 131888-54-5 YM-264 is a selective, potent and orally active platelet-activating factor (PAF) antagonist with a pKi value of 8.85 for rabbit platelet membranes.
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