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| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN22353 | AZ3451 | 2100284-59-9 | AZ3451 is a protease-activated receptor-2 (PAR2) antagonist. |
| CSN22493 | Pumaprazole | 158364-59-1 | Pumaprazole is a reversible proton pump antagonist. |
| CSN22357 | Beperidium Iodide | 86434-57-3 | Beperidium iodide shows a competitive antagonistic effect against acetylcholine receptor with a pA2 of 7.93. |
| CSN22337 | Adavivint | 1467093-03-3 | Adavivint is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells. |
| CSN22322 | (-)-Ketoconazole | 142128-57-2 | (-)-Ketoconazole is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers, levoketoconazole ((2S,4R)-(−)-ketoconazole) and dextroketoconazole ((2R,4S)-(+)-ketoconazole). |
| CSN22471 | Nedocromil Sodium | 69049-74-7 | Nedocromil Sodium is a potent TNF-α inhibitor with an IC50 value of 1.67 μM for Blood eosinophils. |
| CSN22402 | Fodipir | 118248-91-2 | Fodipir is an active metabolite of mangafodipir, involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death. |
| CSN22454 | Lymecycline | 992-21-2 | Lymecycline is a tetracycline derivative, with broad-spectrum antibacterial activity and also has anti-inflammatory property. |
| CSN22371 | Cephalosporin C Zinc Salt | 59143-60-1 | Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC50 of 1.1 μM. |
| CSN22191 | MK-0429 | 227963-15-7 | MK-0429 is a potent integrin antagonist with IC50s of 12.2 nM (α5β1 integrin) and 2.8 nM (αvβ3 integrin), respectively. |
| CSN22204 | Bimosiamose | 187269-40-5 | Bimosiamose is a pan-selectin antagonist, inhibits E-, P-, and L-selectin with IC50s of 88 μM, 20 μM, and 86 μM, respectively, and can be used in the research of inflammatory disease. |
| CSN22375 | Cl-amidine | 913723-61-2 | Cl-amidine is a peptidylarginine deminase (PAD) inhibitor, with an IC50 5.9±0.3 μM for PAD4. |
| CSN22333 | A-69412 | 123606-23-5 | A-69412 is a reversible, specific inhibitor of the hydrophilic 5-lipoxygenase (5-LO). |
| CSN22433 | Iralukast | 151581-24-7 | Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1. |
| CSN22409 | Gefapixant | 1015787-98-0 | Gefapixant is an orally active P2X3 receptor (P2X3R) antagonist with IC50s of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. |
| CSN22527 | TY-51469 | 603987-59-3 | TY-51469 is a chymase inhibitor with IC50s for simian and human chymases of 0.4 and 7.0 nM, respectively. |
| CSN22535 | YM-264 | 131888-54-5 | YM-264 is a selective, potent and orally active platelet-activating factor (PAF) antagonist with a pKi value of 8.85 for rabbit platelet membranes. |
