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Inflammation/Immunology

货号 产品名 CAS号 信息
CSN22353 AZ3451 2100284-59-9 AZ3451 is a protease-activated receptor-2 (PAR2) antagonist.
CSN22493 Pumaprazole 158364-59-1 Pumaprazole is a reversible proton pump antagonist.
CSN22357 Beperidium Iodide 86434-57-3 Beperidium iodide shows a competitive antagonistic effect against acetylcholine receptor with a pA2 of 7.93.
CSN22471 Nedocromil Sodium 69049-74-7 Nedocromil Sodium is a potent TNF-α inhibitor with an IC50 value of 1.67 μM for Blood eosinophils.
CSN22454 Lymecycline 992-21-2 Lymecycline is a tetracycline derivative, with broad-spectrum antibacterial activity and also has anti-inflammatory property.
CSN22143 ERB-196 550997-55-2 ERB-196 is a nonsteroidal selective estrogen receptor-β (ERβ) agonist.
CSN22191 MK-0429 227963-15-7 MK-0429 is a potent integrin antagonist with IC50s of 12.2 nM (α5β1 integrin) and 2.8 nM (αvβ3 integrin), respectively.
CSN22183 DW-1350 491577-61-8 DW-1350 is a LTB4 receptor antagonist.
CSN22201 CI-1044 197894-84-1 CI-1044 is an orally active PDE4 inhibitor with IC50s of 0.29, 0.08, 0.56, 0.09 μM for PDE4A5, PDE4B2, PDE4C2 and PDE4D3, respectively.
CSN22167 BMY-25271 78441-82-4 BMY-25271 is a histamine H2 receptor antagonist.
CSN22204 Bimosiamose 187269-40-5 Bimosiamose is a pan-selectin antagonist, inhibits E-, P-, and L-selectin with IC50s of 88 μM, 20 μM, and 86 μM, respectively, and can be used in the research of inflammatory disease.
CSN22338 AE-3763 291778-77-3 AE-3763 is a peptide-based human neutrophil elastase inhibitor with an IC50 of 29 nM.
CSN22388 E-6123 131614-02-3 E-​6123 is a platelet-activating factor (PAF) receptor antagonist.
CSN22333 A-69412 123606-23-5 A-69412 is a reversible, specific inhibitor of the hydrophilic 5-lipoxygenase (5-LO).
CSN22367 CDK8-IN-3 1884500-15-5 CDK8-IN-3 is an inhibitor of CDK8 extracted from patent WO2016041618A1, compound example 1.7.
CSN22347 AN-3485 1213827-99-6 AN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC50 values ranging from 18 to 580 nM.
CSN22433 Iralukast 151581-24-7 Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.
CSN22419 GNE-4997 1705602-02-3 GNE-4997 is a potent and selective ITK/TSK inhibitor.
CSN22498 ROCK2-IN-2 1995065-79-6 ROCK2-IN-2 is a selective ROCK2 inhibitor extracted from patent US20180093978A1, Compound A-30, has an IC50 of <1 μM.
CSN22527 TY-51469 603987-59-3 TY-51469 is a chymase inhibitor with IC50s for simian and human chymases of 0.4 and 7.0 nM, respectively.
CSN22535 YM-264 131888-54-5 YM-264 is a selective, potent and orally active platelet-activating factor (PAF) antagonist with a pKi value of 8.85 for rabbit platelet membranes.
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