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Human IMP1 (IGF2 mRNA-binding protein 1) originally cloned as ZBP1 [3], is an important RNA-binding protein important for cell RNA localization, migration, stability, and translational control.

IMP1

货号 产品名 CAS号 信息
CSN28421 BTYNB   304456-62-0 MDK6620 is a potent and selective IMP1 inhibitor by inhibiting IMP1 binding to c-Myc mRNA with IC50 value of 5μM. It downregulates several mRNA transcripts regulated by IMP1, resulting in downregulation of c-Myc mRNA and protein, including c-Myc mRNA, β-TrCP1 mRNA, eEF2 mRNA, as well as reducing activation of NF-κB.
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