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| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN19317 | (3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-Trimethyloctahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one | 63968-64-9 | Artemisinin is an inhibitor of HCV subgenomic replicon. It widely used as anti-malarial drug. |
| CSN19360 | 5-Fluorocytosine | 2022-85-7 | 5-Fluorocytosine is an antimycotic prodrug which can be converted to 5-fluorouracil, working by inhibiting DNA and RNA synthesis and interfering with ribosomal protein synthesis. It shows both antifungal and antitumor activity. |
| CSN19416 | Mafenide | 138-39-6 | Mafenide is a sulfonamide-type medication. |
| CSN19477 | D-(+)-Cycloserine | 68-41-7 | D-Cycloserine is a broad-spectrum antibiotic against Gram-negative bacteria working by inhibiting cell wall biosynthesis (D-Ala peptide bond formation). It is also a partial agonist at the glycine modulatory site of NMDA glutamatergic receptors. |
| CSN19490 | Sodium 4-Aminosalicylate Dihydrate | 6018-19-5 | Sodium 4-Aminosalicylate Dihydrate is competitive pteridine synthetase inhibitor with antituberculocis activity. |
| CSN19669 | (S)-2-((2S,3S,4S)-2-Amino-5-(carbamoyloxy)-3,4-dihydroxypentanamido)-2-((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-(hydroxymethyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)acetic acid | 19396-06-6 | Polyoxin B is a competitive inhibitor of chitin synthetase. |
| CSN19926 | Irigenin | 548-76-5 | Irigenin is a naturally occuring O-methylated isoflavone. |
| CSN19721 | Tiamulin | 55297-95-5 | Tiamulin is an antibiotic, and it can inhibit breast cancer growth and pulmonary metastasis by decreasing the activity of Ecto-5'-nucleotidase (CD73). |
| CSN20013 | 3,7-Dihydroxy-9-methoxy-1-methyl-6H-benzo[c]chromen-6-one | 23452-05-3 | Alternariol monomethyl ether displays antifungal, DNA strand-breaking and phytotoxic activity and inhibits actions of topoisomerase IIα in mammalian cell models. |
| CSN20001 | Thiolutin | 87-11-6 | Thiolutin is an antibiotic which inhibits bacterial RNA polymerase. Inhibits adhesion of HUVEC cells to vitronectin (IC50 = 0.83 mM) and subsequently reduces paxillin levels. Thiolutin also suppresses tumor cell-induced angiogenesis. |
| CSN19306 | Sulfamerazine sodium salt | 127-58-2 | Sulfamerazine sodium is a sulfonamide antibacterial. |
| CSN19305 | 4-Amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide | 127-79-7 | Sulfamerazine is a sulfanilamide antibacterial agent working by inhibiting bacterial synthesis of dihydrofolic acid through competing with PABA (para-aminobenzoic acid) for binding to dihydropteroate synthetase (dihydrofolate synthetase). |
| CSN19834 | MK-4965 | 920035-77-4 | MK-4965 is a nonnucleoside reverse transcriptase inhibitor with anti-viral activity. MK-4965 possesses the desired properties for further development as an NNRTI for the treatment of HIV-1 infection. |
| CSN19718 | Virstatin | 88909-96-0 | Virstatin is an anti-cholera substance. |
| CSN20005 | Spinosyn A | 131929-60-7 | Spinosad is an insecticide based on chemical compounds found in the bacterial species Saccharopolyspora spinosa and contains a mix of two spinosoids, spinosyn A, the major component, and spinosyn D (the minor component), in a roughly 17:3 ratio. |
| CSN19831 | Streptomycin | 57-92-1 | Streptomycin is an antibiotic (antimycobacterial) drug, the first of a class of drugs called aminoglycosides to be discovered, and it was the first effective treatment for tuberculosis. |
| CSN19799 | Dexelvucitabine | 134379-77-4 | Dexelvucitabine is a nucleoside reverse transcriptase inhibitor potentially for the treatment of HIV infection. |
| CSN19807 | IDX184 | 1036915-08-8 | IDX 184 is an RNA-directed RNA polymerase (NS5B) inhibitor potentially for the treatment of HCV infection. |
| CSN19823 | Trovafloxacin | 147059-72-1 | Trovafloxacin is a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV. |
| CSN19816 | Actinonin | 13434-13-4 | Actinonin is a bioactive peptide and antibiotic that is a potent inhibitor of CD13 and aminopeptidase (leucine aminopeptidase). |
| CSN19820 | Depulfavirine | 867365-76-2 | RO-0335 is a diphenylether nonnucleoside reverse transcriptase inhibitor. |
| CSN20220 | KDU691 | 1513879-19-0 | KDU691 is a plasmodium PI(4)K inhibitor which selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites. |
| CSN19804 | Tomeglovir | 233254-24-5 | Tomeglovir, a non-nucleoside antiviral, protects against cytomegalovirus (CMV) disease and mortality in immunocompromised guinea pigs. |
| CSN19731 | Dimethyl ((2S,2'S,3R,3'R)-((2S,2'S)-(((2R,5R)-1-(3,5-difluoro-4-(4-(4-fluorophenyl)piperidin-1-yl)phenyl)pyrrolidine-2,5-diyl)bis(5-fluoro-1H-benzo[d]imidazole-6,2-diyl))bis(pyrrolidine-2,1-diyl))bis(3-methoxy-1-oxobutane-1,2-diyl))dicarbamate | 1353900-92-1 | Pibrentasvir is a protease inhibitor potentially for the treatment of HCV infection. |
| CSN20171 | Obefazimod | 1258453-75-6 | ABX-464 is an inhibitor of the HIV replication potentially for the treatment of HIV infection. |
| CSN20002 | Gepotidacin | 1075236-89-3 | Gepotidacin is a first in class triazaacenaphthylene antibiotic that inhibits bacterial type II DNA replication by inhibiting the activity of bacterial topoisomerase and has in vitro activity against susceptible and drug-resistant pathogens. |
| CSN20238 | NJK14047 | 1800576-41-3 | NJK14047 is a selective biphenyl amide p38 MAPK inhibitor which can be used in anti-viral approach targeting hepatitis B virus. |
| CSN19881 | Salvianolic acid C | 115841-09-3 | Salvianolic acid C, a natural product isolated and purified from the root of Salvia miltiorrhiza Bge. with antioxidant effect, exhibits potent XOD inhibitory activity with an IC(50) of 9.07 μM, and enhances the inhibitory effects on sEH might be efficient ways to improve its cardiovascular protective and anti-inflammatory effects. |
| CSN19725 | MMV390048 | 1314883-11-8 | MMV390048 is an antimalarial compound belonging to the aminopyridine class for treating malaria. It is efficacious against all Plasmodium life cycle stages, apart from late hypnozoites in the liver. |
| CSN20239 | Islatravir | 865363-93-5 | MK-8591 exhibits potent activity against HIV. |
| CSN20176 | Tafenoquine | 106635-80-7 | Tafenoquine is an oral active antimalaria drug that is being investigated as a potential treatment for malaria, as well as for malaria prevention. |
| CSN20007 | Piperaquine | 4085-31-8 | Piperaquine is a bisquinoline compound that is often used in combination with artimesinin for inhibition of HIV-1 replication. It inhibits the ex vivo growth of P. falciparum isolates from malaria-infected patients with IC50s ranging from 11.8-217.3 nM. |
| CSN19764 | HBF-0259 | 957011-15-3 | HBF-0259 is an inhibitor of hepatitis B virus surface antigen (HBsAg) secretion. HBF-0259 was identified to inhibit HBsAg with an EC50 of 11.3 μM and a CC50 value of > 50 μM in HepG2.2.15 cells. |
| CSN20008 | Voacamine | 3371-85-5 | Voacamine, isolated from the plant Tabernaemontana coronaria, is an antiprotozoal agent effective against a large array of trypanosomatid parasites including Indian strain of Leishmania donovani and Brazilian strains of Leishmania amazonensis and Trypanosoma cruzi by inhibiting the relaxation activity of topoisomerase IB. |
| CSN19730 | Uprifosbuvir | 1496551-77-9 | Uprifosbuvir is an uridine nucleotide analog HCV NS5B polymerase inhibitor. |
| CSN20003 | SCY-078 | 1207753-03-4 | SCY-078 is an oral glucan synthase inhibitor with antifungal acitivities. |
| CSN20004 | Oteseconazole | 1340593-59-0 | Oteseconazole is a tetrazole antifungal agent potentially for the treatment of candidal vaginal infection by inhibiting sterol 14α-demethylase (CYP51). |
| CSN19678 | Ruzasvir | 1613081-64-3 | Ruzasvir is a potent, Pan-Genotype HCV NS5A inhibitor with Optimized activity against common resistance-associated polymorphisms. |
| CSN20217 | Dndi-vl-2098 | 681492-17-1 | DNDI-VL-2098 is an orally effective preclinical drug candidate for the treatment of visceral leishmaniasis. |
| CSN20229 | LpxC Inhibitor C1(-) | 1219365-61-3 | LpxC inhibitor C1(-) is an inhibitor of Pseudomonas aeruginosa deacetylase LpxC whose cytotoxicity against mammalian cell lines was reduced, solubility and plasma-protein binding (PPB) was improved while retaining potent anti-pseudomonal activity in vitro and in vivo. |
| CSN20236 | KDU731 | 1610610-48-4 | KDU731, a cryptosporidium PI(4)K inhibitor, is a drug candidate for cryptosporidiosis. |
| CSN20213 | N-(3,4-Difluorophenyl)-2-(2-((3-(methylthio)phenyl)amino)-4-oxo-4,5-dihydrothiazol-5-yl)acetamide | 883083-00-9 | IITR08027 is a small molecule which restores the antibacterial activity of fluoroquinolones against multidrug-resistant acinetobacter baumannii by efflux inhibition. |
| CSN20166 | SU11652 | 326914-10-7 | SU11652 is a sunitinib analog with anti-tyrosine-kinase activity, also is identified as a potential inhibitor for Leishmania major (Lm) nucleoside diphosphate kinases NDK and structural studies indicated that this molecule binds to the active site of LmNDK in a similar conformation to nucleotides, mimicking natural substrates. |
| CSN27584 | Methyl 2-(1-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl)-1H-benzo[d]imidazole-6-carboxylate | 2097938-51-5 | R-10015, a broad-spectrum antiviral compound for HIV infection, acts as a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket, with an IC50 of 38 nM for human LIMK1 . |
| CSN19786 | Mesuaxanthone A | 3561-81-7 | Mesuaxanthone A has an anti-Mycobacterium tuberculosis activity. |
| CSN20998 | Dehydropachymic acid | 77012-31-8 | Dehydropachymic acid is extracted from the root of wolfiporia cocos (Schw.) Ryv. with antiinflammatory activity. |
