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Infection

货号 产品名 CAS号 信息
CSN18757 4-Amino-1-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one 7481-89-2 Dideoxycytidine, an analog of pyrimidine, is a nucleoside analog reverse transcriptase inhibitor (NRTI) with antiretroviral activity.
CSN18776 NM107 20724-73-6 NM107 is an inhibitor of HCV RNA replication with IC50 of 7.0 μM.
CSN18777 Telbivudine 3424-98-4 Telbivudine selectively inhibits hepatitis B virus (HBV) reverse transcriptase and is used in the treatment of hepatitis B infection.
CSN18884 BM212 146204-42-4 BM212 is a pyrrole-derived antimycobacterial with strong inhibitory activity against bothMycobacterium tuberculosis and some nontuberculosis mycobacteria.
CSN19097 NQ301 130089-98-4 NQ301, a selective CD45 inhibitor with an IC50 of 200 nM, is also an antithrombotic agent and inhibits collagen-challenged rabbit platelet aggregation with an IC50 of 10 mg/mL.
CSN18765 Procodazole 23249-97-0 Procodazole is a non-specific active immunoprotective agent against viral and bacterial infections, used as a potentiator.
CSN18670 SAMT-247 850715-59-2 SAMT-247 inhibits HIV by modifying the nucleocapsid NCp7 region of Gag in infected cells, blocking Gag processing and reducing infectivity.
CSN18676 (3S,6R,7R,22R,23S,26S,36R,38aR)-3-(2-Amino-2-oxoethyl)-44-[[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-α-L-lyxo-hexopyranosyl)-β-D-glucopyranosyl]oxy]-10,19-dichloro-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-[[(2R)-4-methyl-2-(methylamino)-1-oxopentyl]amino]-2,5,24,38,39-pentaoxo-22H-8,11:18,21-Dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid xhydrochloride 1404-93-9 Vancomycin HCl is a HCl of vancomycin that is a narrow-spectrum glycopeptide antibacterial agent.
CSN18726 Pashanone 42438-78-8 Pashanone possesses moderate antifungal activity.
CSN19187 SC75741 913822-46-5 SC75741 is a novel NF-kappaB inhibitor.
CSN19267 (2S,5R,6R)-6-[(R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 69-53-4 Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of Gram-positive and Gram-negative bacteria.
CSN18664 Doravirine 1338225-97-0 Doravirine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase with potent activity against wild-type virus (95% inhibitory concentration 19 nM, 50% human serum).
CSN18550 AVX 13616 900814-48-4 AVX 13616 shows the potent in vivo antibacterial activity of Avexa's lead antibacterial candidate and particularly against drug-resistant Staphylococcus pathogens.
CSN18887 RSV604 racemate 676128-62-4 RSV604 racemate is a racemic mixture, shows less potency against strains of respiratory syncytial virus (RSV) than the S-isomer.
CSN18403 Bephenium 7181-73-9 Bephenium is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis and a B-type AChR activator.
CSN18888 RSV604 (R enantiomer) 932108-20-8 RSV604 R-enantiomer is the R-enantiomer of RSV604. RSV604 is an inhibitor of respiratory syncytial virus (RSV) replication. R-enantiomer is less active against RSV.
CSN18886 Beclabuvir 958002-33-0 Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM.
CSN18409 BMS-707035 729607-74-3 BMS-707035 is a potent, specific, reversible HIV-I integrase inhibitor with IC50 value of 15 nM.
CSN18883 Apramycin Sulfate 65710-07-8 Apramycin sulfate(1:x) is an aminoglycoside antibiotic mproduced by a strain of Streptomyces tenebrarius, used in veterinary practice.
CSN18471 Danoprevir 850876-88-9 Danoprevir, a peptidomimetic, is an inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2 nM - 3.5 nM.
CSN18385 RSV604 676128-63-5 RSV604 is an inhibitor of respiratory syncytial virus replication (EC50=0.86 μM) and a putative RSV nucleoprotein (N) inhibitor.
CSN18586 Vaniprevir 923590-37-8 Vaniprevir is a non-covalent competitive inhibitor of the hepatitis C virus (HCV) NS3/4A protease.
CSN18885 Antibiotic-5d 251349-54-9 Antibiotic-5d is a synthesis and antimicrobial compound.
CSN18479 TMC353121 857066-90-1 TMC353121 is a potent RSV fusion inhibitor with pEC50 of 9.9 (t1/2 in lung = 25 h).
CSN18639 LEDGIN6 957890-42-5 HIV-1 integrase inhibitor, in the treatment of human immunodeficiency virus (HIV) infection.
CSN19292 (4S,4aS,5aR,12aS)-9-(2-(tert-Butylamino)acetamido)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 220620-09-7 Tigecycline is a glycylcycline-class antibiotic used for a number of bacterial infections.
CSN18574 Letermovir 917389-32-3 Letermovir is an anti-CMV compound which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors.
CSN18889 3-(Hexadecyloxy)propyl hydrogen ((((S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonate 444805-28-1 CMX001 was developed as an orally active, lipophilic form of cidofovir (CDV) and has enhanced activity in vitro and in vivo compared to CDV against certain herpesviruses, adenoviruses and orthopoxviruses.
CSN18890 Apramycin 37321-09-8 Apramycin is an aminoglycoside antibiotic used in veterinary medicine.
CSN18700 Lagociclovir 92562-88-4 Lagociclovir is a prodrug of 3'-fluoro-2',3'-dideoxyguanosine with high oral bioavailability in humans and potent activity against HBV.
CSN18720 Tolclofos-methyl 57018-04-9 Tolclofos-methyl is a broad-spectrum aromatic hydrocarbon fungicide that is used as a see treatment for protection against soil-borne and seed borne fungal pathogens that caused seed decay and seedling blights.
CSN18351 Cephalexin hydrochloride 59695-59-9 Cefalexin HCl is a cephalosporin antibiotic.
CSN18496 Fostemsavir Tris 864953-39-9 BMS-663068 tris is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.
CSN18507 Tecovirimat 869572-92-9 Tecovirimat is a potent, selective and orally bioavailable antipoxvirus compound active against multiple orthopoxviruses, including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), and variola viruses, with EC50 value of 0.01μM for Vaccinia virus in CPE assays.
CSN18498 Narlaprevir 865466-24-6 Narlaprevir is a potent, selective, orally bioavailable NS3 protease inhibitor (Ki=6 nM; EC90=40 nM).
CSN18683 Ethambutol 2HCl 1070-11-7 Ethambutol 2HCl is an antitubercular agent working by inhibiting the transfer of mycolic acids into the cell wall of the tubercle bacillus.
CSN18806 TMC647055 1204416-97-6 TMC647055 choline is a cell-permeating, selective HCV NS5B inhibitor, eliciting a mean IC50 of 34 nM, as assessed in the RdRp primer-dependent transcription assay.
CSN18863 Artefenomel 1029939-86-3 Artefenomel is an antimalarial ozonide artefenomel which can maintain the rapid onset of action and potent activity of the artemisinin derivatives while exhibits greatly improved pharmacokinetics, low projected cost of goods, prophylactic activity, and the potential for a single dose cure.
CSN18867 Inarigivir soproxil 942123-43-5 SB-9200 has a broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus and influenza and has demonstrated activity against hepatitis B virus (HBV) in vitro and in vivo.
CSN18891 KIN1408 1903800-11-2 KIN1408 is an antiviral small molecule compound, as agonists of the RLR pathway.
CSN19259 PEX14 Inhibitor Derivative 6 1884470-47-6 PEX14 inhibitor derivative 6 may disrupte interactions between two of the proteins involved in peroxisome biogenesis (PEX5 and PEX14), which permits import of glycosomal matrix proteins from the cytoplasm.
CSN19112 DL-threo-2-methylisocitrate sodium N/A DL-threo-2-methylisocitrate is a substrate of isocitrate lyase 1 (ICL1).
CSN19284 Voxilaprevir 1535212-07-7 Voxilaprevir is used for the treatment of Hepatitis C virus infection.
CSN19278 Mrl-436 2095432-38-3 MRL-436 is a small molecule which binds to RNAP through a binding site that differs from the rifampin binding site, inhibits rifampin-resistant RNAP derivatives, and exhibits antibacterial activity against rifampin-resistant strains.
CSN19273 Avibactam sodium hydrate 2938989-90-1 Avibactam sodium is a covalent, reversible β-lactamase inhibitor, inhibits β-lactamase TEM-1 and CTX-M-15 with IC50 of 8 nM and 5 nM, respectively.
CSN19282 APE1 Inhibitor C10 1227098-30-7 APE1 inhibitor C10 is a small molecular inhibitor which has a potent in treating Kaposi's sarcoma-associated herpesvirus (KSHV).
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