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货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN17739 | Presatovir | 1353625-73-6 | Presatovir is a novel inhibitor of respiratory syncytial virus (RSV) fusion F protein with potent antiviral activity against a broad range of strains, working by binding to F protein on the viral surface. |
CSN17757 | Elbasvir | 1370468-36-2 | Elbasvir is an inhibitor of nonstructural protein 5A (NS5A) of hepatitis C virus (HCV). It can be used to treat chronic HCV infection. |
CSN17956 | Tebipenem | 161715-21-5 | Tebipenem is a broad-spectrum antibiotic, from the carbapenem subgroup of β-lactam antibiotics. |
CSN17975 | Sitafloxacin hydrate | 163253-35-8 | Sitafloxacin Hydrate is a fluoroquinolone antibiotic with promising effect on the treatment of Buruli ulcer. |
CSN18067 | Oritavancin diphosphate | 192564-14-0 | Oritavancin diphosphate is a semisynthetic glycopeptide antibiotic being developed for the treatment of serious Gram-positive bacterial infections. |
CSN17997 | Sutezolid | 168828-58-8 | Sutezolid is an oxazolidinone antimicrobial being developed for the treatment of tuberculosis. |
CSN17753 | BQ-123 | 136553-81-6 | BQ-123 is a specific antagonist of endothelin A receptor (ETA) and the IC50 is 7.3 nM. |
CSN18061 | Helioxanthin | 18920-47-3 | Helioxanthin and analogues have been demonstrated to suppress gene expression of human hepatitis B virus. |
CSN17865 | GSK2838232 | 1443460-91-0 | GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates, |
CSN17826 | (+)-Ketoconazole | 142128-59-4 | (+)-Ketoconazole is an imidazole anti-fungal agent, a CYP3A4 inhibitor. |
CSN17820 | (±)-BI-D | 1416258-16-6 | (±)-BI-D is a potent ALLINI (An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site. |
CSN18231 | Pritelivir | 348086-71-5 | BAY 57-1293 represents a potent inhibitor of herpes simplex virus (HSV) that target the virus helicase primase complex. |
CSN17713 | DCVC | 13419-46-0 | DCVC E-isomer inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro. |
CSN17701 | PF 1022A | 133413-70-4 | PF-1022A is a N-methylated cyclooctadepsipeptides (CODPs) with strong anthelmintic properties and acts as an ionophore. |
CSN17721 | Stavudine sodium | 134624-73-0 | Stavudine sodium is a nucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. |
CSN18180 | DPC-681 | 284661-68-3 | DPC-681 is a potent and selective inhibitor of HIV protease with IC90s for wild-type HIV-1 of 4 to 40 nM. |
CSN17607 | Tenofovir maleate | 1236287-04-9 | Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. |
CSN18227 | Nucleozin | 341001-38-5 | Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication. |
CSN17899 | Ledipasvir D-tartrate | 1502654-87-6 | Ledipasvir D-tartrate is an inhibitor of the hepatitis C virus NS5A protein, which is an experimental drug for the treatment of hepatitis C. |
CSN17771 | Ribocil | 1381289-58-2 | Ribocil is a highly selective chemical modulator of bacterial riboflavin riboswitches. Ribocil strongly inhibits GFP expression, achieving a 50% effective concentration (EC50) of 0.3 μM. |
CSN17648 | MUT056399 | 1269055-85-7 | MUT056399 is a highly potent inhibitor of the FabI enzyme of both S. aureus and E. coli with 50% inhibitory concentration IC50s of 12 nM and 58 nM, respectively. |
CSN18216 | BRD7116 | 329059-55-4 | BRD7116 competitively binds to bacterial DNA gyrase, exhibits an EC50 of 200 nM for LSCe cells, with cell-non-autonomous anti-leukemia activity. |
CSN17941 | Fluconazole mesylate | 159532-41-9 | Fluconazole mesylate is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. |
CSN17642 | CDK9-IN-2 | 1263369-28-3 | CDK9-IN-2 is a special cyclin-dependent kinase 9 (CDK9) inhibitor with an IC50 of 5 nM and 7 nM in H929 multiple myeloma(MM) cell line (72 hours) and A2058 skin cell line (72 hours), respectively. |
CSN18016 | Bevirimat | 174022-42-5 | Bevirimat is an anti-HIV drug derived from a betulinic acid-like compound, and is believed to inhibit HIV by a so-called maturation inhibition mechanism. |
CSN17729 | Grazoprevir hydrate | 1350462-55-3 | MK-5172 is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development. |
CSN17815 | CDK9-IN-1 | 1415559-43-1 | CDK9-IN-1 is a selective CDK9 inhibitor for the treatment of HIV infection. |
CSN17867 | ALS-8112 | 1445379-92-9 | ALS-8112 is a potent and selective respiratory syncytial virus (RSV) polymerase inhibitor. The 5'-triphosphate of ALS-8112 inhibits RSV polymerase with an IC50 of 0.02 μM. |
CSN18302 | D77 | 497836-10-9 | D77 is anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75. D77 inhibits HIV-1(IIIB) replication by EC50 value of 23.8 μg/mL in MT-4 cell (5.03 μg/mL for C8166 cells). |
CSN18304 | SQ109 | 502487-67-4 | SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC50 for cell killing of 50±8 nM. |
CSN17868 | Lumicitabine | 1445385-02-3 | ALS-8176 an inhibitor of the respiratory syncytial virus (RSV) polymerase. |
CSN18057 | Pafuramidine | 186953-56-0 | Pafuramidine is an orally bioavailable prodrug of furamidine, which has clinical activity against Pneumocystis pneumonia. |
CSN18288 | Lersivirine | 473921-12-9 | Lersivirine is a next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI, IC50=119 nM) with a unique resistance profile that exhibits potent antiretroviral activity against wild-type human immunodeficiency virus and clinically relevant NNRTI-resistant strains. |
CSN18276 | Anguizole | 442666-98-0 | Anguizole is a small molecule inhibitor of HCV replication and alters NS4B's subcellular distribution. |
CSN17992 | Anidulafungin | 166663-25-8 | Anidulafungin is an echinocandin antifungal agent used to treat invasive Aspergillus infection, working by inhibiting (1→3)-β-D-glucan synthase, an enzyme important to the synthesis of the fungal cell wall. |
CSN18092 | Helioxanthin derivative 5-4-2 | 203935-39-1 | Helioxanthin derivative 5-4-2 is an analogue of helioxanthin, exhibites significant in vitro anti-HBV activity with EC50 of 0.08 μM in HepG2.2.15 cells. |
CSN18126 | Galidesivir HCl | 222631-44-9 | BCX 4430 HCl is a viral RNA-dependent RNA polymerase (RdRp) inhibitor and demonstrats broad-spectrum activity in multiple viruses and a favorable preliminary preclinical safety profile. |
CSN17832 | Grazoprevir sodium salt | 1425038-27-2 | MK-5172 sodium is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development. |
CSN18006 | Dalbavancin | 171500-79-1 | Dalbavancin is a semisynthetic lipoglycopeptide with potent activity against Gram-positive bacteria(MIC50=0.06 mg/L; B. anthracis). |
CSN18305 | Pentamidine 2HCl | 50357-45-4 | Pentamidine 2HCl is an antimicrobial agent. |
CSN17897 | Trovirdine | 149488-17-5 | Trovirdine inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate. |
CSN18162 | Bruceine A | 25514-31-2 | Bruceine A is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.) and is a potential candidate for the treatment of canine babesiosis. |
CSN17954 | Sibofimloc | 1616113-45-1 | Antibiotic-202 is an antibiotic compound, for treating bacterial infections. |
CSN18322 | Hetacillin potassium | 5321-32-4 | Hetacillin potassium is a broad-spectrum treatment for use against a wide range of common Gram-positive and Gram-negative bacteria. |
CSN18047 | Ribocil-C | 1825355-56-3 | Ribocil-C is a highly selective chemical modulator of bacterial riboflavin riboswitches. |
CSN17925 | Fluconazole hydrate | 155347-36-7 | Fluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. |
CSN18120 | UKI-1 | 220355-63-5 | UKI-1 is a synthetic inhibitor of the urokinase-type plasminogen activator system. |
CSN18076 | Tigecycline HCl | 197654-04-9 | Tigecycline HCl is a first-in-class, broad spectrum antibiotic with activity against antibiotic-resistant organisms. |
CSN18255 | Omadacycline | 389139-89-3 | Omadacycline is a tetracycline antibiotic in the pipeline, which can inhibit the 30s subunit of bacterial ribosome. |
CSN17804 | Tylosin phosphate | 1405-53-4 | Tylosin phosphate is a broad spectrum antibiotic against Gram-positive organisms and a limited range of Gram-negative organisms. |