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Infection

货号 产品名 CAS号 信息
CSN17739 Presatovir 1353625-73-6 Presatovir is a novel inhibitor of respiratory syncytial virus (RSV) fusion F protein with potent antiviral activity against a broad range of strains, working by binding to F protein on the viral surface.
CSN17757 Elbasvir 1370468-36-2 Elbasvir is an inhibitor of nonstructural protein 5A (NS5A) of hepatitis C virus (HCV). It can be used to treat chronic HCV infection.
CSN17956 Tebipenem 161715-21-5 Tebipenem is a broad-spectrum antibiotic, from the carbapenem subgroup of β-lactam antibiotics.
CSN17975 Sitafloxacin hydrate 163253-35-8 Sitafloxacin Hydrate is a fluoroquinolone antibiotic with promising effect on the treatment of Buruli ulcer.
CSN18067 Oritavancin diphosphate 192564-14-0 Oritavancin diphosphate is a semisynthetic glycopeptide antibiotic being developed for the treatment of serious Gram-positive bacterial infections.
CSN17997 Sutezolid 168828-58-8 Sutezolid is an oxazolidinone antimicrobial being developed for the treatment of tuberculosis.
CSN17753 BQ-123 136553-81-6 BQ-123 is a specific antagonist of endothelin A receptor (ETA) and the IC50 is 7.3 nM.
CSN18061 Helioxanthin 18920-47-3 Helioxanthin and analogues have been demonstrated to suppress gene expression of human hepatitis B virus.
CSN17865 GSK2838232 1443460-91-0 GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates,
CSN17826 (+)-Ketoconazole 142128-59-4 (+)-Ketoconazole is an imidazole anti-fungal agent, a CYP3A4 inhibitor.
CSN17820 (±)-BI-D 1416258-16-6 (±)-BI-D is a potent ALLINI (An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site.
CSN18231 Pritelivir 348086-71-5 BAY 57-1293 represents a potent inhibitor of herpes simplex virus (HSV) that target the virus helicase primase complex.
CSN17713 DCVC 13419-46-0 DCVC E-isomer inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro.
CSN17701 PF 1022A 133413-70-4 PF-1022A is a N-methylated cyclooctadepsipeptides (CODPs) with strong anthelmintic properties and acts as an ionophore.
CSN17721 Stavudine sodium 134624-73-0 Stavudine sodium is a nucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
CSN18180 DPC-681 284661-68-3 DPC-681 is a potent and selective inhibitor of HIV protease with IC90s for wild-type HIV-1 of 4 to 40 nM.
CSN17607 Tenofovir maleate 1236287-04-9 Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
CSN18227 Nucleozin 341001-38-5 Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.
CSN17899 Ledipasvir D-tartrate 1502654-87-6 Ledipasvir D-tartrate is an inhibitor of the hepatitis C virus NS5A protein, which is an experimental drug for the treatment of hepatitis C.
CSN17771 Ribocil 1381289-58-2 Ribocil is a highly selective chemical modulator of bacterial riboflavin riboswitches. Ribocil strongly inhibits GFP expression, achieving a 50% effective concentration (EC50) of 0.3 μM.
CSN17648 MUT056399 1269055-85-7 MUT056399 is a highly potent inhibitor of the FabI enzyme of both S. aureus and E. coli with 50% inhibitory concentration IC50s of 12 nM and 58 nM, respectively.
CSN18216 BRD7116 329059-55-4 BRD7116 competitively binds to bacterial DNA gyrase, exhibits an EC50 of 200 nM for LSCe cells, with cell-non-autonomous anti-leukemia activity.
CSN17941 Fluconazole mesylate 159532-41-9 Fluconazole mesylate is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
CSN17642 CDK9-IN-2 1263369-28-3 CDK9-IN-2 is a special cyclin-dependent kinase 9 (CDK9) inhibitor with an IC50 of 5 nM and 7 nM in H929 multiple myeloma(MM) cell line (72 hours) and A2058 skin cell line (72 hours), respectively.
CSN18016 Bevirimat 174022-42-5 Bevirimat is an anti-HIV drug derived from a betulinic acid-like compound, and is believed to inhibit HIV by a so-called maturation inhibition mechanism.
CSN17729 Grazoprevir hydrate 1350462-55-3 MK-5172 is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.
CSN17815 CDK9-IN-1 1415559-43-1 CDK9-IN-1 is a selective CDK9 inhibitor for the treatment of HIV infection.
CSN17867 ALS-8112 1445379-92-9 ALS-8112 is a potent and selective respiratory syncytial virus (RSV) polymerase inhibitor. The 5'-triphosphate of ALS-8112 inhibits RSV polymerase with an IC50 of 0.02 μM.
CSN18302 D77 497836-10-9 D77 is anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75. D77 inhibits HIV-1(IIIB) replication by EC50 value of 23.8 μg/mL in MT-4 cell (5.03 μg/mL for C8166 cells).
CSN18304 SQ109 502487-67-4 SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC50 for cell killing of 50±8 nM.
CSN17868 Lumicitabine 1445385-02-3 ALS-8176 an inhibitor of the respiratory syncytial virus (RSV) polymerase.
CSN18057 Pafuramidine 186953-56-0 Pafuramidine is an orally bioavailable prodrug of furamidine, which has clinical activity against Pneumocystis pneumonia.
CSN18288 Lersivirine 473921-12-9 Lersivirine is a next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI, IC50=119 nM) with a unique resistance profile that exhibits potent antiretroviral activity against wild-type human immunodeficiency virus and clinically relevant NNRTI-resistant strains.
CSN18276 Anguizole 442666-98-0 Anguizole is a small molecule inhibitor of HCV replication and alters NS4B's subcellular distribution.
CSN17992 Anidulafungin 166663-25-8 Anidulafungin is an echinocandin antifungal agent used to treat invasive Aspergillus infection, working by inhibiting (1→3)-β-D-glucan synthase, an enzyme important to the synthesis of the fungal cell wall.
CSN18092 Helioxanthin derivative 5-4-2 203935-39-1 Helioxanthin derivative 5-4-2 is an analogue of helioxanthin, exhibites significant in vitro anti-HBV activity with EC50 of 0.08 μM in HepG2.2.15 cells.
CSN18126 Galidesivir HCl 222631-44-9 BCX 4430 HCl is a viral RNA-dependent RNA polymerase (RdRp) inhibitor and demonstrats broad-spectrum activity in multiple viruses and a favorable preliminary preclinical safety profile.
CSN17832 Grazoprevir sodium salt 1425038-27-2 MK-5172 sodium is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.
CSN18006 Dalbavancin 171500-79-1 Dalbavancin is a semisynthetic lipoglycopeptide with potent activity against Gram-positive bacteria(MIC50=0.06 mg/L; B. anthracis).
CSN18305 Pentamidine 2HCl 50357-45-4 Pentamidine 2HCl is an antimicrobial agent.
CSN17897 Trovirdine 149488-17-5 Trovirdine inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate.
CSN18162 Bruceine A 25514-31-2 Bruceine A is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.) and is a potential candidate for the treatment of canine babesiosis.
CSN17954 Sibofimloc 1616113-45-1 Antibiotic-202 is an antibiotic compound, for treating bacterial infections.
CSN18322 Hetacillin potassium 5321-32-4 Hetacillin potassium is a broad-spectrum treatment for use against a wide range of common Gram-positive and Gram-negative bacteria.
CSN18047 Ribocil-C 1825355-56-3 Ribocil-C is a highly selective chemical modulator of bacterial riboflavin riboswitches.
CSN17925 Fluconazole hydrate 155347-36-7 Fluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
CSN18120 UKI-1 220355-63-5 UKI-1 is a synthetic inhibitor of the urokinase-type plasminogen activator system.
CSN18076 Tigecycline HCl 197654-04-9 Tigecycline HCl is a first-in-class, broad spectrum antibiotic with activity against antibiotic-resistant organisms.
CSN18255 Omadacycline 389139-89-3 Omadacycline is a tetracycline antibiotic in the pipeline, which can inhibit the 30s subunit of bacterial ribosome.
CSN17804 Tylosin phosphate 1405-53-4 Tylosin phosphate is a broad spectrum antibiotic against Gram-positive organisms and a limited range of Gram-negative organisms.
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