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Integrin
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN13433 | TR-14035 | 232271-19-1 | TR-14035 is a dual antagonist of both integrin α4β7 and integrin α4β1 with IC50 values of 7 nM and 87 nM, respectively, used as an anti-inflammatory agent. |
| CSN12096 | Tirofiban | 144494-65-5 | Tirofiban is a non-peptide reversible antagonist of the platelet integrin glycoprotein (GP) IIb/IIIa receptor used as an antiplatelet drug. |
| CSN12097 | Tirofiban HCl H2O | 150915-40-5 | Tirofiban HCl H2O is a non-peptide reversible antagonist of the platelet integrin glycoprotein (GP) IIb/IIIa receptor used as an antiplatelet drug. |
| CSN22191 | MK-0429 | 227963-15-7 | MK-0429 is a potent integrin antagonist with IC50s of 12.2 nM (α5β1 integrin) and 2.8 nM (αvβ3 integrin), respectively. |
| CSN19077 | Leukadherin-1 | 344897-95-6 | Leukadherin-1 is allosteric activator of CD11b/CD18 with EC50 value of 4 μM for increasing CD11b/CD18-dependent cell adhesion to fibrinogen. |
| CSN20182 | GLPG0187 | 1644644-90-5 | GLPG0187 is a small molecule integrin receptor antagonist (IRA) with potential antineoplastic activity and inhibits αvβ1-integrin with an IC50 of 1.3 nM. |
| CSN10925 | Eptifibatide | 188627-80-7 | Eptifibatide is a specific inhibitor of fibrinogen working by binding to the platelet membrane integrin αIIbβ3 receptor and preventing platelet aggregation. |
| CSN22550 | Eptifibatide Acetate | 881997-86-0 | Eptifibatide Acetate is a cyclic heptapeptide that shows the inhibition of platelet glycoprotein IIb/IIIa in acute coronary syndromes. |
| CSN19215 | Cyclo(RGDyK) | 250612-42-1 | Cyclo(RGDyK) is a highly potent and selective inhibitor for the αvβ3 integrin with a IC50 of 0.94 nM. |
| CSN19214 | Cyclo(-RGDfK) Trifluoroacetate | 500577-51-5 | Cyclo(-RGDfK) Trifluoroacetate is a highly potent and selective inhibitor for the αvβ3 integrin with a IC50 of 0.94 nM. |
| CSN17206 | CWHM-12 | 1564286-55-0 | CWHM-12 is a small molecule inhibitor of αV integrins with IC50s of 1.8/0.8/1.5/0.2 nM for αvβ1/αvβ3/αvβ8, and is less potency on αvβ5 (IC50=61 nM) and on inhibition on αIIbβ3/α2β1/α10β1. |
| CSN19182 | Cilengitide Trifluoroacetate | 199807-35-7 | Cilengitide Trifluoroacetate is a cyclic RGD pentapeptide antagonist of integrins αvβ3, αvβ5 and α5β1. |
| CSN17349 | Cilengitide | 188968-51-6 | Cilengitide is a cyclic RGD pentapeptide antagonist of integrins αvβ3, αvβ5 and α5β1. |
| CSN18167 | ATN-161 | 262438-43-7 | ATN-161 is a five-amino-acid peptide derived from the synergy region of fibronectin and a beta integrin antagonist with antitumor activity. |
| CSN10335 | Arg-Gly-Asp-Ser | 91037-65-9 | Arg-Gly-Asp-Ser (RGDS) is a synthetic integrin antagonist, a specific peptide motif through which extracellular matrix (ECM) components interact with integrin and can modify the behavior of cells. |
| CSN23536 | Arg-Gly-Asp TFA | 120103-89-1 | Arg-Gly-Asp TFA is the TFA salt form of Arg-Gly-Asp, which is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins. |
| CSN10333 | Arg-Gly-Asp | 99896-85-2 | Arg-Gly-Asp is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins. |
| CSN16418 | A-205804 | 251992-66-2 | A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively. |
