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Integrin

Integrin

货号 产品名 CAS号 信息
CSN13160 Zaurategrast 455264-31-0 Zaurategrast is an oral α4-integrin inhibitor.
CSN13433 TR-14035 232271-19-1 TR-14035 is a dual antagonist of both integrin α4β7 and integrin α4β1 with IC50 values of 7 nM and 87 nM, respectively, used as an anti-inflammatory agent.
CSN12096 Tirofiban 144494-65-5 Tirofiban is a non-peptide reversible antagonist of the platelet integrin glycoprotein (GP) IIb/IIIa receptor used as an antiplatelet drug.
CSN12097 Tirofiban hydrochloride monohydrate 150915-40-5 Tirofiban HCl H2O is a non-peptide reversible antagonist of the platelet integrin glycoprotein (GP) IIb/IIIa receptor used as an antiplatelet drug.
CSN32450 Zalunfiban 1448313-27-6 RUC-4 is an aIIbß3 antagonist for prehospital therapy of myocardial infarction.
CSN22191 MK-0429 227963-15-7 MK-0429 is a potent integrin antagonist with IC50s of 12.2 nM (α5β1 integrin) and 2.8 nM (αvβ3 integrin), respectively.
CSN21154 Lifitegrast 1025967-78-5 Lifitegrast is a novel small molecule integrin antagonist which can inhibit an integrin, lymphocyte function-associated antigen 1 (LFA-1), from binding to intercellular adhesion molecule 1 (ICAM-1).
CSN19077 Leukadherin-1 344897-95-6 Leukadherin-1 is allosteric activator of CD11b/CD18 with EC50 value of 4 μM for increasing CD11b/CD18-dependent cell adhesion to fibrinogen.
CSN18350 Integrin Antagonists 27 593274-97-6 Integrin antagonist 27 is a small molecule integrin αvβ3 antagonist with binding affinity of 18 nM, as an anticancer agent.
CSN17970 (S)-3-(3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl)-4-((R)-3-(2-(1,5,6,7-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic acid xhydrochloride 1629249-40-6 Integrin antagonist 1 HCl is a small molecule integrin αvβ6 antagonist.
CSN13784 SB-273005 205678-31-5 In vitro, SB273005 inhibits human osteoclast-mediated bone resorption with IC50 of 11 nM.
CSN32609 Soyasapogenol C 595-14-2 ICAM1 Expression Inhibitors
CSN28434 GLPG0187 1320346-97-1 GLPG 0187 is a potent αv integrin inhibitor with IC50 values of 1.2-3.7 nM. It inhibits osteoclastic bone resorption and angiogenesis in vitro and in vivo. Also it suppresses epithelial-mesenchymal transition (EMT) and migration of PC-3M-Pro4/luc cells, without inhibiting cell growth.
CSN21652 Fradafiban 148396-36-5 Fradafiban is a glycoprotein IIb/IIIa receptor antagonist.
CSN17362 Firategrast 402567-16-2 Firategrast is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system (CNS).
CSN10925 Eptifibatide 188627-80-7 Eptifibatide is a specific inhibitor of fibrinogen working by binding to the platelet membrane integrin αIIbβ3 receptor and preventing platelet aggregation.
CSN22550 Eptifibatide xAcetate 881997-86-0 Eptifibatide Acetate is a cyclic heptapeptide that shows the inhibition of platelet glycoprotein IIb/IIIa in acute coronary syndromes.
CSN18950 E7820 289483-69-8 E7820 is an angiogenesis inhibitor by suppressing integrin a2, a cell adhesion molecule expressed on endothelial cells.
CSN19215 Cyclo(RGDyK) trifluoroacetate 250612-42-1 Cyclo(RGDyK) is a highly potent and selective inhibitor for the αvβ3 integrin with a IC50 of 0.94 nM.
CSN19214 Cyclo(-RGDfK) TFA 500577-51-5 Cyclo(-RGDfK) Trifluoroacetate is a highly potent and selective inhibitor for the αvβ3 integrin with a IC50 of 0.94 nM.
CSN17951 Cyclo(-RGDfK) 161552-03-0 Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin.
CSN17206 CWHM-12 1564286-55-0 CWHM-12 is a small molecule inhibitor of αV integrins with IC50s of 1.8/0.8/1.5/0.2 nM for αvβ1/αvβ3/αvβ8, and is less potency on αvβ5 (IC50=61 nM) and on inhibition on αIIbβ3/α2β1/α10β1.
CSN19182 Cilengitide TFA 199807-35-7 Cilengitide Trifluoroacetate is a cyclic RGD pentapeptide antagonist of integrins αvβ3, αvβ5 and α5β1.
CSN17349 Cilengitide 188968-51-6 Cilengitide is a cyclic RGD pentapeptide antagonist of integrins αvβ3, αvβ5 and α5β1.
CSN32619 BMS-688521 893397-44-9 Cell Adhesion Inhibitors, LFA-1/ICAM-1 Interaction Inhibitors
CSN32628 BIRT 377 213211-10-0 Cell Adhesion Inhibitors, LFA-1 Antagonists, LFA-1/ICAM-1 Interaction Inhibitors, Signal Transduction Modulators
CSN18555 ATN-161 trifluoroacetate salt 904763-27-5 ATN-161 trifluoroacetate is a five-amino-acid peptide derived from the synergy region of fibronectin and a beta integrin antagonist with antitumor activity.
CSN18167 ATN-161 262438-43-7 ATN-161 is a five-amino-acid peptide derived from the synergy region of fibronectin and a beta integrin antagonist with antitumor activity.
CSN10335 Arg-Gly-Asp-Ser 91037-65-9 Arg-Gly-Asp-Ser (RGDS) is a synthetic integrin antagonist, a specific peptide motif through which extracellular matrix (ECM) components interact with integrin and can modify the behavior of cells.
CSN23536 Arg-Gly-Asp TFA 120103-89-1 Arg-Gly-Asp TFA is the TFA salt form of Arg-Gly-Asp, which is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.
CSN10333 RGD 99896-85-2 Arg-Gly-Asp is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.
CSN24771 ADH-503   2055362-74-6 ADH-503 is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression.
CSN16418 A-205804 251992-66-2 A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.
CSN67365 BMS-587101 509083-77-6
CSN83369 Tirofiban hydrochloride 142373-60-2
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