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JAK
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN18107 | WHI-P97 | 211555-05-4 | WHI-P97 is a rationally designed potent inhibitor of JAK-3. |
| CSN20642 | SD1029 | 118372-34-2 | SD1029 is a cell-permeable xanthenedione compound that acts as a JAK2-selective inhibitor. |
| CSN16800 | Pyridone 6 | 457081-03-7 | Pyridone 6 is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM) displaying significantly weaker affinities(130 nM to 10 mM) for other protein tyrosine kinases. |
| CSN23211 | ZM 449829 | 4452-06-6 | Potent, selective JAK3 inhibitor |
| CSN23010 | NSC 33994 | 82058-16-0 | NSC 33994 is a selective inhibitor of JAK2 with IC50 of 60 nM. |
| CSN23158 | TCS 21311 | 1260181-14-3 | NIBR3049, also known as TCS-21311, is a potent and selective JAK3 inhibitor IC50 values of 8 nM.. |
| CSN23767 | JAK3-IN-6 | 1443235-95-7 | JAK3-IN-6 is an irreversible, potent and highly selective JAK3 inhibitor with IC50 value of 0.15 nM, 4300-fold selective for JAK3 over JAK1 in enzyme assays. |
| CSN18801 | FLLL32 | 1226895-15-3 | FLLL32 is a potent JAK2/STAT3 inhibitor with IC50 of < 5 μM. |
| CSN19204 | Cerdulatinib HCl | 1369761-01-2 | Cerdulatinib HCl is a dual JAK/SYK inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. It also inhibits other kinases with IC50 less than 200 nM. |
| CSN17120 | AZ 960 | 905586-69-8 | AZ 960 is a potent ATP-competitive JAK inhibitor with IC50 values of <3 nM and 9nM for JAK2 and JAK3, respectively. |
| CSN22692 | Atiprimod 2HCl | 130065-61-1 | Atiprimod 2HCl is an inhibitor JAK2 with IC50 of 397 nM. |
| CSN17038 | (3S,4S)-Tofacitinib | 1092578-47-6 | (3S,4S)-Tofacitinib is an isomer of tofacitinib, an inhibitor of JAK3 with IC50 of 1 nM, 20- to 100-fold less potent against JAK2 and JAK1. |
| CSN17455 | (3S,4R)-Tofacitinib | 1092578-48-7 | (3S,4R)-Tofacitinib is an isomer of tofacitinib, which is an inhibitor of JAK3 with IC50 of 1 nM, 20- to 100-fold less potent against JAK2 and JAK1. |
| CSN17037 | (3R,4S)-Tofacitinib | 1092578-46-5 | (3R,4S)-Tofacitinib is an isomer of tofacitinib, an inhibitor of JAK3 with IC50 of 1 nM, 20- to 100-fold less potent against JAK2 and JAK1. |
| CSN19970 | Curculigoside | 85643-19-2 |
