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JNK
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN22565 | Vacquinol-1 | 5428-80-8 | Vacquinol-1 is an activator of MKK4-dependent macropinocytotic cell death in glioblastoma cells. |
CSN23129 | SR-3576 | 1164153-22-3 | SR-3576 is a potent JNK3 inhibitor that is highly selective over p38. |
CSN17482 | SR-3306 | 1128096-91-2 | SR-3306 is a brain penetrant small molecule JNK inhibitor from the aminopyrimidine class. |
CSN12230 | SP600125 | 129-56-6 | SP-600125 is a competitive and reversible JNK inhibitor with IC50 values of 40 nM, 40 nM and 90 nM for JNK1, 2 and 3. |
CSN26187 | Sesamolin | 526-07-8 | Sesamolin is a furofuran lignan extracted from sesame seeds, which has beneficial physiological properties such as antioxidant, anti-mutagenic, anti-aging and anti-inflammatory activities. It was also found to inhibit lipid peroxidation in rat liver and kidney. |
CSN23136 | SU3327 | 40045-50-9 | Selective JNK inhibitor |
CSN17808 | JNK-IN-8 | 1410880-22-6 | JNK-IN-8 is a potent, selective and irreversible JNK inhibitor with IC50 values of 4.7 nM, 18.7 nM and 1 nM for JNK1, 2 and 3, respectively. |
CSN17806 | JNK-IN-7 | 1408064-71-0 | JNK-IN-7 is a potent inhibitor for JNK all isoforms with IC50 values of 1.5, 2 and 0.7 nM for JNK1, JNK2 and JNK3, respectively. |
CSN23162 | JNK Inhibitor VIII | 894804-07-0 | JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively, and has IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively. |
CSN23162 | JNK Inhibitor VIII | 894804-07-0 | JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively, and has IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively. |
CSN15772 | TCS JNK 5a | 312917-14-9 | JNK Inhibitor IX can selectively inhibit JNK2 and JNK3 through targeting the ATP binding site with pIC50 of 6.5 and 6.7, respectively. |
CSN22865 | JIP-1(153-163) | 438567-88-5 | JIP-1 (153-163) is a peptide inhibitor of c-Jun N-terminal kinase. |
CSN18143 | IQ-1S free acid | 23146-22-7 | IQ-1S Free Acid is a selective JNK3 inhibitor with IC50 value of 87 nM, with less potency against JNK 1/2 with IC50 values of 390/360nM. |
CSN22859 | IQ-3 | 312538-03-7 | IQ 3 is a selective JNK3 inhibitor with Kd of 66 nM. |
CSN22858 | IQ 1S | 1421610-21-0 | IQ 1S is a JNK inhibitor with Kd of 87, 360 and 390 nM for JNK3, JNK2 and JNK1, respectively. |
CSN19488 | Ginsenoside Re | 52286-59-6 | Ginsenoside Re is a panaxatriol saponin that has diverse in vitro and in vivo effects, including vasorelaxant, antioxidant, antihyperlipidemic, and angiogenic actions. |
CSN17254 | DB07268 | 929007-72-7 | DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM. |
CSN22748 | CEP-1347 | 156177-65-0 | CEP 1347 is an inhibitor of c-jun N-terminal kinase (JNK) signaling. |
CSN17363 | Tanzisertib | 899805-25-5 | CC-930 is a selective ATP-competitive JNK inhibitor with IC50 values of 61nM, 5nM and 5nM for JNK1, 2 and 3, respectively. |
CSN16122 | CC-401 | 395104-30-0 | CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity. |
CSN17322 | CC-401 hydrochloride | 1438391-30-0 | CC-401 HCl is a selective and ATP-competitive JNK inhibitor with Ki values ranging in 25-50 nM. |
CSN13428 | BI-78D3 | 883065-90-5 | BI-78D3 is a selective and competitive JNK inhibitor with IC50 of 280 nM. |
CSN18465 | Bentamapimod | 848344-36-5 | AS-602801 is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively. |
CSN18229 | AS601245 | 345987-15-7 | AS-601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK) (hJNK1: IC50=150nM, hJNK2: IC50=220nM and hJNK3: IC50=70 nM), has neuroprotective properties. |
CSN10317 | Anisomycin | 22862-76-6 | Anisomycin is a naturally occuring antibiotic which can act as a potent activator of stress-activated protein kinases (JNK/SAPK) and p38 MAPK, and also can inhibit protein synthesis by blocking translation. |
CSN22669 | AEG3482 | 63735-71-7 | AEG 3482 is an inhibitor of c-jun N-terminal kinase (JNK) signaling. |