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JNK
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN12230 | SP-600125 | 129-56-6 | SP-600125 is a competitive and reversible JNK inhibitor with IC50 values of 40 nM, 40 nM and 90 nM for JNK1, 2 and 3. |
| CSN23136 | SU 3327 | 40045-50-9 | Selective JNK inhibitor |
| CSN14309 | Juglanin | 5041-67-8 | Juglanin, a natural product isolated and purified from the herbs of Phymatopteris hastate with antioxidant activity, shows protective effects on fructose-induced hepatitis by inhibiting inflammation and apoptosis through TLR4 and JAK2/STAT3 signaling pathways in fructose-fed rats, and can lead to G2/M phase arrest, induce apoptosis as well as autophagy through the ROS/JNK signaling pathway in human breast cancer cells, it may be a promising candidate for development of anti-tumor drugs targeting breast cancer. |
| CSN23162 | TCS JNK 6o | 894804-07-0 | JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively, and has IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively. |
| CSN23162 | TCS JNK 6o | 894804-07-0 | JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively, and has IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively. |
| CSN15772 | JNK Inhibitor IX | 312917-14-9 | JNK Inhibitor IX can selectively inhibit JNK2 and JNK3 through targeting the ATP binding site with pIC50 of 6.5 and 6.7, respectively. |
| CSN18143 | IQ-1S Free Acid | 23146-22-7 | IQ-1S Free Acid is a selective JNK3 inhibitor with IC50 value of 87 nM, with less potency against JNK 1/2 with IC50 values of 390/360nM. |
| CSN17322 | CC-401 HCl | 1438391-30-0 | CC-401 HCl is a selective and ATP-competitive JNK inhibitor with Ki values ranging in 25-50 nM. |
| CSN13428 | BI-78D3 | 883065-90-5 | BI-78D3 is a selective and competitive JNK inhibitor with IC50 of 280 nM. |
| CSN18465 | AS-602801 | 848344-36-5 | AS-602801 is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively. |
| CSN18229 | AS-601245 | 345987-15-7 | AS-601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK) (hJNK1: IC50=150nM, hJNK2: IC50=220nM and hJNK3: IC50=70 nM), has neuroprotective properties. |
| CSN10317 | Anisomycin | 22862-76-6 | Anisomycin is a naturally occuring antibiotic which can act as a potent activator of stress-activated protein kinases (JNK/SAPK) and p38 MAPK, and also can inhibit protein synthesis by blocking translation. |
| CSN22669 | AEG 3482 | 63735-71-7 | AEG 3482 is an inhibitor of c-jun N-terminal kinase (JNK) signaling. |