欢迎来到CSNpharm!产品仅用于科研!

400-920-2911 sales@csnpharm.cn

0

K-Ras (G12C)/PROTAC refers to the PROTAC target K-Ras (G12C).

K-Ras (G12C)/PROTAC

货号 产品名 CAS号 信息
CSN27182 LC-2 2502156-03-6 LC-2 is the first PROTAC capable of degrading endogenous KRAS(G12C). It covalently binds KRASG12C with a MRTX849 warhead and recruits the E3 ligase VHL, inducing rapid and sustained KRASG12C degradation leading to suppression of MAPK signaling in both homozygous and heterozygous KRASG12C cell lines.
<< PREV 1 NEXT >>
联系
我们