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LPL Receptor
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN18599 | TY-52156 | 934369-14-9 | TY-52156 is a potent S1P3 receptor antagonist in a competitive manner, and the Ki value is estimated to be 110 nM for S1P3 receptor. |
| CSN32570 | LX-2932 | 1055027-48-9 | Sphingosine 1-Phosphate Receptor 1 (S1PR1; EDG1) Ligands |
| CSN32572 | W-146 | 909725-64-0 | Sphingosine 1-Phosphate Receptor 1 (S1PR1; EDG1) Antagonists |
| CSN32564 | BMS-520 | 1236188-38-7 | Sphingosine 1-Phosphate Receptor 1 (S1PR1; EDG1) Agonists |
| CSN23705 | Sphingosine-1-phosphate | 26993-30-6 | Sphingosine 1-phosphate is the product of phosphorylation of sphingosine by sphingosine kinase and ligand for EDG-1 and EDG-3 and activator of GPR3, GPR6, and GPR12. |
| CSN32517 | Siponimod fumarate | 1234627-85-0 | Siponimod, sold under the brand name Mayzent, is a selective sphingosine-1-phosphate receptor modulator for oral use that is used for multiple sclerosis (MS). It is intended for once-daily oral administration. |
| CSN10124 | SEW2871 | 256414-75-2 | SEW2871 is a potent and selective sphingosine-1-phosphate 1 (S1P1) receptor agonist. Activates S1P1 receptor with an EC50 of 13 nM, but does not activate S1P2, S1P3, S1P4 or S1P5 receptors at concentrations up to 10 μM. Cell-permeable and active in vivo. |
| CSN32516 | Ozanimod HCl | 1618636-37-5 | Ozanimod, sold under the brand name Zeposia, is an immunomodulatory medication for the treatment of relapsing multiple sclerosis (RMS) and ulcerative colitis.It acts as a sphingosine-1-phosphate (S1P) receptor agonist, sequestering lymphocytes to peripheral lymphoid organs and away from their sites of chronic inflammation. |
| CSN18971 | ONO-7300243 | 638132-34-0 | ONO-7300243 is a potent LPA1 (Lysophosphatidic Acid Receptor) antagonist with an IC50 of 160 nM. |
| CSN23237 | JTE 013 | 383150-41-2 | JTE 013 is a potent, selective S1P2 receptor antagonist with IC50 value of 17.6 nM. |
| CSN32535 | Fingolimod phosphate | 402615-91-2 | FTY720 Phosphate is a derivative of ISP-1 that is a fungal metabolite as well as a structural analog of sphingosine. |
| CSN25873 | FTY720 (R)-Phosphate | 402616-23-3 | FTY720 (R)-Phosphate is the phosphate form of R-FTY720. Fingolimod is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells. |
| CSN12321 | Fingolimod | 162359-55-9 | Fingolimod is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells. |
| CSN16720 | Fingolimod HCl | 162359-56-0 | Fingolimod HCl is a S1P antagonist with IC50 of 0.033 nM. |
| CSN16720 | Fingolimod HCl | 162359-56-0 | Fingolimod HCl is a S1P antagonist with IC50 of 0.033 nM. |
| CSN32511 | 1,4-Dicaffeoylquinic acid | 1182-34-9 | Cynarin comes from the flowerbud of Lonicera japonica Thunb. It has antioxidant property and inhibites HIV-1 replication in MT-2 cell culture at non-toxic concentrations, a potent and highly selective class of HIV-1 integrase inhibitors. |
| CSN32513 | BMS-986104 | 1622180-31-7 | BMS-986104 is a potent and selective S1P1 receptor modulator, which demonstrates ligand-biased signaling and differentiates from 1 in terms of cardiovascular and pulmonary safety based on preclinical pharmacology while showing equivalent efficacy in a T-cell transfer colitis model. Mechanistically, BMS-986104 exhibited excellent remyelinating effects on lysophosphatidylcholine (LPC) induced demyelination in a three-dimensional brain cell culture assay. |
| CSN32530 | S1P1 agonist 8 | 402616-26-6 | Agonist for Sphingosine 1-Phosphate receptors 1; Immunosuppressants |
