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LPL Receptor

LPL Receptor

货号 产品名 CAS号 信息
CSN18599 TY-52156 934369-14-9 TY-52156 is a potent S1P3 receptor antagonist in a competitive manner, and the Ki value is estimated to be 110 nM for S1P3 receptor.
CSN32570 LX-2932 1055027-48-9 Sphingosine 1-Phosphate Receptor 1 (S1PR1; EDG1) Ligands
CSN32572 W-146 909725-64-0 Sphingosine 1-Phosphate Receptor 1 (S1PR1; EDG1) Antagonists
CSN32564 BMS-520 1236188-38-7 Sphingosine 1-Phosphate Receptor 1 (S1PR1; EDG1) Agonists
CSN23705 Sphingosine-1-phosphate 26993-30-6 Sphingosine 1-phosphate is the product of phosphorylation of sphingosine by sphingosine kinase and ligand for EDG-1 and EDG-3 and activator of GPR3, GPR6, and GPR12.
CSN32517 Siponimod fumarate 1234627-85-0 Siponimod, sold under the brand name Mayzent, is a selective sphingosine-1-phosphate receptor modulator for oral use that is used for multiple sclerosis (MS). It is intended for once-daily oral administration.
CSN10124 SEW2871 256414-75-2 SEW2871 is a potent and selective sphingosine-1-phosphate 1 (S1P1) receptor agonist. Activates S1P1 receptor with an EC50 of 13 nM, but does not activate S1P2, S1P3, S1P4 or S1P5 receptors at concentrations up to 10 μM. Cell-permeable and active in vivo.
CSN32516 Ozanimod HCl 1618636-37-5 Ozanimod, sold under the brand name Zeposia, is an immunomodulatory medication for the treatment of relapsing multiple sclerosis (RMS) and ulcerative colitis.It acts as a sphingosine-1-phosphate (S1P) receptor agonist, sequestering lymphocytes to peripheral lymphoid organs and away from their sites of chronic inflammation.
CSN18971 ONO-7300243 638132-34-0 ONO-7300243 is a potent LPA1 (Lysophosphatidic Acid Receptor) antagonist with an IC50 of 160 nM.
CSN23237 JTE 013 383150-41-2 JTE 013 is a potent, selective S1P2 receptor antagonist with IC50 value of 17.6 nM.
CSN32535 Fingolimod phosphate 402615-91-2 FTY720 Phosphate is a derivative of ISP-1 that is a fungal metabolite as well as a structural analog of sphingosine.
CSN25873 FTY720 (R)-Phosphate 402616-23-3 FTY720 (R)-Phosphate is the phosphate form of R-FTY720. Fingolimod is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells.
CSN12321 Fingolimod 162359-55-9 Fingolimod is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells.
CSN16720 Fingolimod HCl   162359-56-0 Fingolimod HCl is a S1P antagonist with IC50 of 0.033 nM.
CSN16720 Fingolimod HCl   162359-56-0 Fingolimod HCl is a S1P antagonist with IC50 of 0.033 nM.
CSN32511 1,4-Dicaffeoylquinic acid 1182-34-9 Cynarin comes from the flowerbud of Lonicera japonica Thunb. It has antioxidant property and inhibites HIV-1 replication in MT-2 cell culture at non-toxic concentrations, a potent and highly selective class of HIV-1 integrase inhibitors.
CSN32513 BMS-986104 1622180-31-7 BMS-986104 is a potent and selective S1P1 receptor modulator, which demonstrates ligand-biased signaling and differentiates from 1 in terms of cardiovascular and pulmonary safety based on preclinical pharmacology while showing equivalent efficacy in a T-cell transfer colitis model. Mechanistically, BMS-986104 exhibited excellent remyelinating effects on lysophosphatidylcholine (LPC) induced demyelination in a three-dimensional brain cell culture assay.
CSN32530 S1P1 agonist 8 402616-26-6 Agonist for Sphingosine 1-Phosphate receptors 1; Immunosuppressants
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