LRRK2
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN19704 | MLi-2 | 1627091-47-7 | MLi-2 is a highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity. |
CSN15891 | LRRK2-IN-1 | 1234480-84-2 | LRRK2-IN-1 is a potent and selective LRRK2 inhibitor with IC50 values of 6 and 13 nM for G2019S mutant and wild-type LRRK2, respectively. |
CSN17916 | GNE-9605 | 1536200-31-3 | GNE-9605 is a selective and potent LRRK2 with IC50 value of 18.7 nM. |
CSN16309 | CZC-54252 | 1191911-27-9 | CZC-54252 is a potent LRRK2 inhibitor with IC50 values of 1.28 nM and 1.85 nM for wild-type and G2019S mutant LRRK2, respecitively, possessing neuroprotective effect. |
CSN17277 | CZC-25146 | 1191911-26-8 | CZC-25146 is a potent LRRK2 inhibitor with IC50 values of 4.76 and 6.87 nM for for wild-type and G2019S mutant LRRK2, respectively. It also inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2. |