Leucine-rich Repeat Kinase 2 | Autophagy| CSNpharm

LRRK2

LRRK2
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货号	产品名	CAS号	信息
CSN19704	MLi-2	1627091-47-7	MLi-2 is a highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity.
CSN15891	LRRK2-IN-1	1234480-84-2	LRRK2-IN-1 is a potent and selective LRRK2 inhibitor with IC50 values of 6 and 13 nM for G2019S mutant and wild-type LRRK2, respectively.
CSN17916	GNE-9605	1536200-31-3	GNE-9605 is a selective and potent LRRK2 with IC50 value of 18.7 nM.
CSN16309	CZC-54252	1191911-27-9	CZC-54252 is a potent LRRK2 inhibitor with IC50 values of 1.28 nM and 1.85 nM for wild-type and G2019S mutant LRRK2, respecitively, possessing neuroprotective effect.
CSN17277	CZC-25146	1191911-26-8	CZC-25146 is a potent LRRK2 inhibitor with IC50 values of 4.76 and 6.87 nM for for wild-type and G2019S mutant LRRK2, respectively. It also inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2.