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Receptor with a tyrosine-protein kinase activity. Following activation by ALKAL1 or ALKAL2 ligands at the cell surface, transduces an extracellular signal into an intracellular response. Ligand-binding to the extracellular domain induces tyrosine kinase activation, leading to activation of the mitogen-activated protein kinase pathway. Phosphorylates almost exclusively at the first tyrosine of the Y-x-x-x-Y-Y motif.

LTK

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