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LXR

LXR

货号 产品名 CAS号 信息
CSN17950 SR-9243 1613028-81-1 SR9243 is a LXR inverse agonist that induces LXR-corepressor interaction and shows anticancer activity and selectively targets the warburg effect and lipogenesis.
CSN23133 SR 9238 1416153-62-2 SR9238 is a potent synthetic LXR antagonist with IC50s of 214 nM and 43 nM for LXRα and LXRβ respectively.
CSN23678 RGX104 Free Acid 610318-54-2 RGX104 free acid is an agonist of liver-X nuclear hormone receptor (LXR), it can regulate the immune process by activating the ApoE gene.
CSN16661 LXR-623 875787-07-8 LXR-623 is a novel and brain-penetrant LXR agonist with IC50 values of 179 and 24 nM for LXRα and LXRβ, respectively.
CSN16055 Ethyl 2,4,6-Trihydroxybenzoate 90536-74-6 Ethyl 2,4,6-trihydroxybenzoate, a natural product isolated and purified from the herbs of Celtis biondii, suppresses cellular cholesterol accumulation in a dose-dependent manner and induces the transcriptional activation of LXR-α/-β-responsive genes, and is a dual-LXR modulator that regulates the expression of key genes in cholesterol homeostasis in multiple cells without inducing lipid accumulation in HepG2 cells.
CSN20272 27-Hydroxycholesterol 20380-11-4 27-Hydroxycholesterol is an endogenous oxysterol with multiple biological functions, including activity as a selective estrogen receptor modulator (SERM) (a mixed, tissue-specific agonist-antagonist of the estrogen receptor (ER)) and as an agonist of the liver X receptor (LXR). It is a metabolite of cholesterol that is produced by the enzyme CYP27A1.
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