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LXR
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN17950 | SR9243 | 1613028-81-1 | SR9243 is a LXR inverse agonist that induces LXR-corepressor interaction and shows anticancer activity and selectively targets the warburg effect and lipogenesis. |
| CSN23133 | SR9238 | 1416153-62-2 | SR9238 is a potent synthetic LXR antagonist with IC50s of 214 nM and 43 nM for LXRα and LXRβ respectively. |
| CSN21423 | Rovazolac | 1454288-88-0 | Rovazolac is a modulator of liver x receptor (LXR). |
| CSN23678 | RGX-104 | 610318-54-2 | RGX104 free acid is an agonist of liver-X nuclear hormone receptor (LXR), it can regulate the immune process by activating the ApoE gene. |
| CSN22495 | RGX-104 hydrochloride | 610318-03-1 | RGX-104 is a small-molecule LXR agonist that modulates innate immunity via transcriptional activation of the ApoE gene. |
| CSN16661 | LXR-623 | 875787-07-8 | LXR-623 is a novel and brain-penetrant LXR agonist with IC50 values of 179 and 24 nM for LXRα and LXRβ, respectively. |
| CSN15972 | GW3965 | 405911-09-3 | GW3965 is a potent, selective LXR agonist for hLXRα and hLXRβ with EC50 of 190 and 30 nM, respectively. |
| CSN12844 | GW3965 hydrochloride | 405911-17-3 | GW3965 HCl is a selective and non-steroidal LXR agonist with EC50 values of 190 and 30 nM for hLXRα and hLXRβ, respectively. |
| CSN22840 | GSK2033 | 1221277-90-2 | GSK 2033 is a potent LXR antagonist with pIC50 of 7.5. |
| CSN16055 | Ethyl 2,4,6-Trihydroxybenzoate | 90536-74-6 | Ethyl 2,4,6-trihydroxybenzoate, a natural product isolated and purified from the herbs of Celtis biondii, suppresses cellular cholesterol accumulation in a dose-dependent manner and induces the transcriptional activation of LXR-α/-β-responsive genes, and is a dual-LXR modulator that regulates the expression of key genes in cholesterol homeostasis in multiple cells without inducing lipid accumulation in HepG2 cells. |
| CSN19058 | BMS-779788 | 918348-67-1 | BMS-779788 is a LXR partial agonist with IC50 values of 68 nM for LXRα and 14 nM for LXRβ. |
| CSN19056 | AZ876 | 898800-26-5 | AZ876 is a high-affinity LXR agonist. |
| CSN20272 | 27-Hydroxycholesterol | 20380-11-4 | 27-Hydroxycholesterol is an endogenous oxysterol with multiple biological functions, including activity as a selective estrogen receptor modulator (SERM) (a mixed, tissue-specific agonist-antagonist of the estrogen receptor (ER)) and as an agonist of the liver X receptor (LXR). It is a metabolite of cholesterol that is produced by the enzyme CYP27A1. |
| CSN50578 | GSK3987 | 264206-85-1 |
