Mouse Double minute 2 Homolog | Apoptosis| CSNpharm

MDM2

MDM2
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货号	产品名	CAS号	信息
CSN23123	SP 141	1253491-42-7	SP-141 is a MDM2 inhibitor. It acts by exerting excellent in-vitro and in-vivo anticancer activity.
CSN18271	SJ-172550	431979-47-4	SJ-172550 is a small molecule inhibitor of MDMX and competes for the wild type p53 peptide binding to MDMX with an EC50 of 5 μM.
CSN19741	PK11195	85532-75-8	PK11195 is a 2‑Phenylindolylglyoxylyldipeptide Murine Double Minute2 (MDM2)/Translocator Protein (TSPO)/Human Constitutive Androstane Receptor (hCAR) Inhibitor, and is potentially useful for the Treatment of Gliomas.
CSN20477	NSC 66811	6964-62-1	NSC 66811 is a potent MDM2 inhibitor with Ki value of 120 nM which can disrupt MDM2-p53 interaction and activate p53 function.
CSN17369	NSC 59984	803647-40-7	NSC 59984 is a reactivator of p53 which targets various mutant p53 to restore wild-type p53 pathway via the activation of p73 in cancer cells. It could induce p53 mutant protein degradation via MDM2-mediated ubiquitination.