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| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN21474 | α-MSH | 581-05-5 | α-MSH is endogenous agonist of melanocortin receptor with Ki values of 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively. |
| CSN24285 | α-MSH TFA | 171869-93-5 | α-MSH is endogenous agonist of melanocortin receptor with Ki values of 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively. |
| CSN27581 | THIQ | 312637-48-2 | THIQ is the first selective agonist of the melanocortin-4 receptor (MC4R), with high affinity and potency for hMC4R (IC50=1.2 nM, EC50=2.1 nM) and rMC4R (IC50=0.6 nM, EC50=2.9 nM). THIQ maintains low potency at MC1R, MC3R and MC5R. THIQ plays a role in eliciting erectile activity in rodents. THIQ acts as a pharmacoperone of the MC4R rescuing the cell surface expression and signaling of some intracellularly retained MC4R mutants . |
| CSN26192 | SHU 9119 | 168482-23-3 | SHU 9119 is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC50 values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively. It induces cAMP formation in HEK293 cells expressing human MC1R (EC50 = 1.11 nM), but inhibits cAMP formation in cells expressing human MC4R. |
| CSN20790 | Melanotan (MT)-II | 121062-08-6 | Melanotan II, an analog of α-melanocyte stimulating hormone, is agonist of MC3-R/MC4-R melanocortin that induces melanogenesis and thus increases skin pigmentation. |
| CSN21457 | Melanotan I | 75921-69-6 | Melanotan I, a synthetic analog of α-MSH, is an agonist of melanocortin receptors with Ki values of 0.085, 0.4, 3.8 and 5.1 nM for MC1, MC3, MC4 and MC5 receptors respectively. |
| CSN17945 | Bremelanotide Acetate | 1607799-13-2 | Bremelanotide acetate is a melanocortin agonist. |
| CSN21460 | Adrenocorticotropic Hormone (ACTH) (1-39), human | 12279-41-3 | ACTH (1-39) is agonist of melanocortin receptor 2 (MC2R) with an EC50 of 57 pM in HeLa cells expressing the mouse receptor. |
| CSN24141 | Adrenocorticotropic Hormone (ACTH) (1-39), rat | 77465-10-2 | ACTH (1-39) (mouse, rat) is a potent melanocortin 2 (MC2) receptor agonist. |
| CSN21458 | ACTH (1-13) | 22006-64-0 | ACTH (1-13) is a peptide fragment of adrenocorticotropic hormone with cytoprotective effects. |
| CSN21434 | Adrenocorticotropic Hormone (ACTH) (1-10), human | 2791-05-1 | ACTH (1-10), human is an agonist of melanocortin receptor 3 (MC3R) and MC4R with EC50s of 2.6 and 200 nM, respectively. |
