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mGluR
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN15882 | VU0361737 | 1161205-04-4 | VU 0361737 is a brain-penetrant and selective positive allosteric modulator of mGlu4 receptors with EC50 values of 240 nM. |
| CSN12115 | Topiramate | 97240-79-4 | Topiramate is a selective GluK1 kainate receptors (GluR5) antagonist with IC50 value of 0.46 μM which can act as a positive allosteric modulator of GABAA receptor-mediated currents, inhibit Nav channels and L-type Ca2+ channels. |
| CSN15700 | Basimglurant | 802906-73-6 | RG7090 is a potent, selective and orally available mGlu5 negative allosteric modulator with a Kd of 1.1 nM. |
| CSN13647 | MTEP HCl | 1186195-60-7 | MTEP HCl is a potent, selective and non-competitive mGlu5 antagonist with IC50 and Ki of 5 nM and 16 nM, respectively. |
| CSN11477 | MPEP | 96206-92-7 | MPEP is a potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. |
| CSN15940 | MPEP HCl | 219911-35-0 | MPEP HCl is a potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype with IC50 of 36 nM. |
| CSN12419 | LY404039 | 635318-11-5 | LY404039 is an inhibitor for mGluR1 (Ki=149 nM) and mGluR2 (Ki= 92 nM), which can also inhibit dopamine receptor. |
| CSN22956 | LY367385 | 198419-91-9 | LY367385 is a selective mGlu1a receptor antagonist. |
| CSN11347 | LY341495 | 201943-63-7 | LY341495 is a highly potent and selective group II metabotropic glutamate receptor antagonist. |
| CSN11296 | Sodium (S)-2-amino-4-carboxybutanoate | 142-47-2 | L-Glutamic Acid Monosodium is an excitatory amino acid neurotransmitter as an agonist at GluR and NMDA receptor. |
| CSN22816 | Fenobam | 57653-26-6 | Fenobam is a potent and selective non-competitive mGlu5 negative allosteric modulator. |
| CSN10975 | Evans Blue | 314-13-6 | Evans blue is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). |
| CSN13492 | D-Glutamine | 5959-95-5 | D-Glutamine is a non-essential amino acid involved in many metabolic processes such as forming the central metabolite in amino acid transamination. |
| CSN13419 | CPPHA | 693288-97-0 | CPPHA is a selective positive allosteric modulator of mGluR5 receptor. |
| CSN12708 | Biphenylindanone A | 866823-73-6 | Biphenylindanone A is a research agent which acts as a potent and selective positive allosteric modulator for the group II metabotropic glutamate receptor subtype mGluR2. |
| CSN16906 | (2R,4R)-APDC | 169209-63-6 | (2R,4R)-APDC is a highly potent and highly selective agonist for mGluR-2 (group II metabotropic glutamate receptors). The compound is useful for investigating the functions of metabotropic glutamate receptors in situ.(2R,4R)-APDC inhibits the NADPH-oxidase dependent ROS system.(2R,4R)-APDC is an activator of mGluR-3. |
