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NADPH Oxidase
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN21151 | VAS2870 | 722456-31-7 | VAS2870 is a specific and effect NADPH oxidase inhibitor with IC50 value of 10.6 µM against NOX activity in human neutrophil lysates. |
| CSN21291 | ML171 | 6631-94-3 | ML171 is a novel and selective NOX1 inhibitor with IC50 value of 0.25 μM for blocking NOX1-dependent ROS generation in a HEK293-NOX1 recombinant cell system. |
| CSN18816 | GSK2795039 | 1415925-18-6 | GSK2795039 is a small molecule NADPH Oxidase 2 Inhibitor. |
| CSN22127 | GLX351322 | 835598-94-2 | GLX351322 is an inhibitor of NADPH oxidase 4, inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μ M. |
| CSN13646 | Setanaxib | 1218942-37-0 | GKT137831 is a specific dual Nox1/Nox4 inhibitor with Ki of 140±40 nM and 110±30 nM and a potent inhibitor of fibrosis and hepatocyte apoptosis. |
| CSN25216 | Fluorofenidone | 848353-85-5 | Fluorofenidone attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and ECM deposition via the PI3K/Akt signalling pathway, suggesting AKF-PD is a potential novel therapeutic agent against renal fibrosis. |
| CSN20206 | BJ-1301 | 1287234-48-3 | BJ-1301 is a promising candidate for the management of tumor agiongenesis and growth via inhibition of RTK and NADPH oxidase activities. |
| CSN25329 | APX-115 free base | 1270084-92-8 | APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. |
| CSN12681 | Apocynin | 498-02-2 | Apocynin is potent and selective NADPH-oxidase inhibitor with IC50 value of 10 μM. |
| CSN14626 | 8-Epideoxyloganic acid | 88668-99-9 | 8-Epideoxyloganic acid, a natural product isolated and purified from the herb of Lamiophlomis rotata, with anti-inflammatory activity, weak antinociceptive activity and bioactivities of analgesia, homeostasis, has the potential to serve as anti-inflammatory agents during oxidative stress, the inhibition of ROS production, possibly through modulation of NOX activity and/or the radical scavenging effect, and beta2 integrin expression in leucocytes. |
