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Neurological Disease

货号 产品名 CAS号 信息
CSN22437 JNJ-46778212 1363281-27-9 JNJ-46778212 is an mGlu5 positive allosteric modulator with an EC50 of 260 nM.
CSN22374 CI-943 89239-35-0 CI-943 is a potential antipsychotic agent.
CSN22241 NBQX 118876-58-7 NBQX is a potent, selective and competitive AMPAR antagonist, which shows activity of neuroprotective and anticonvulsant.
CSN22445 L-APB 23052-81-5 L-APB is a potent and specific agonist for the group III mGluRs, with EC50s of 0.13±0.02, 0.29±0.07, 1.0±0.3, 249±107 μM for mGlu4, mGlu8, mGlu6 and mGlu7 receptors, respectively.
CSN22913 MMPEP 823198-78-3 MPEP HCl is both a selective non-competitive mGlu5 receptor antagonist with IC50 value of 36 nM, and a mGlu4 receptor positive allosteric modulator.
CSN22187 W-2429 37795-69-0 W-2429 is a non-narcotic analgesic agent.
CSN22216 NS1652 1566-81-0 NS1652 is a reversible anion conductance inhibitor, blocks chloride channel, with an IC50 of 1.6 μM in human and mouse red blood cells.
CSN22401 Fluxametamide 928783-29-3 Fluxametamide is an insecticide with wide spectrum, acts as an antagonist of GABA- and glutamate-gated chloride channels, with IC50 of 1.95  nM and 225  nM for M. domestica GABACls and GluCls.
CSN22323 (+)-Dihydrexidine HCl 158704-02-0 (+)-Dihydrexidine HCl is a dopamine D1 receptor agonist with an EC50 of 72± 21 nM.
CSN22469 MSOP 66515-29-5 MSOP is a selective group III metabotropic glutamate receptor antagonist with apparent KD of 51 μM for the L-AP4-sensitive presynaptic mGluR.
CSN22538 β-Secretase Inhibitor IV 797035-11-1 β-Secretase Inhibitor IV is a potent, cell-active BACE-1 inhibitor with IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively.
CSN23242 Cyromazin 66215-27-8 Cyromazine is a triazine insecticide and an acaricide.
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