| CSN22437 |
JNJ-46778212
|
1363281-27-9 |
JNJ-46778212 is an mGlu5 positive allosteric modulator with an EC50 of 260 nM. |
| CSN22374 |
CI-943
|
89239-35-0 |
CI-943 is a potential antipsychotic agent. |
| CSN22241 |
NBQX
|
118876-58-7 |
NBQX is a potent, selective and competitive AMPAR antagonist, which shows activity of neuroprotective and anticonvulsant. |
| CSN22445 |
L-APB
|
23052-81-5 |
L-APB is a potent and specific agonist for the group III mGluRs, with EC50s of 0.13±0.02, 0.29±0.07, 1.0±0.3, 249±107 μM for mGlu4, mGlu8, mGlu6 and mGlu7 receptors, respectively. |
| CSN22913 |
MMPEP
|
823198-78-3 |
MPEP HCl is both a selective non-competitive mGlu5 receptor antagonist with IC50 value of 36 nM, and a mGlu4 receptor positive allosteric modulator. |
| CSN22187 |
W-2429
|
37795-69-0 |
W-2429 is a non-narcotic analgesic agent. |
| CSN22216 |
NS1652
|
1566-81-0 |
NS1652 is a reversible anion conductance inhibitor, blocks chloride channel, with an IC50 of 1.6 μM in human and mouse red blood cells. |
| CSN22401 |
Fluxametamide
|
928783-29-3 |
Fluxametamide is an insecticide with wide spectrum, acts as an antagonist of GABA- and glutamate-gated chloride channels, with IC50 of 1.95 nM and 225 nM for M. domestica GABACls and GluCls. |
| CSN22323 |
(+)-Dihydrexidine HCl
|
158704-02-0 |
(+)-Dihydrexidine HCl is a dopamine D1 receptor agonist with an EC50 of 72± 21 nM. |
| CSN22469 |
MSOP
|
66515-29-5 |
MSOP is a selective group III metabotropic glutamate receptor antagonist with apparent KD of 51 μM for the L-AP4-sensitive presynaptic mGluR. |
| CSN22538 |
β-Secretase Inhibitor IV
|
797035-11-1 |
β-Secretase Inhibitor IV is a potent, cell-active BACE-1 inhibitor with IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively. |
| CSN23242 |
Cyromazin
|
66215-27-8 |
Cyromazine is a triazine insecticide and an acaricide. |
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