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NOS

NOS

货号 产品名 CAS号 信息
CSN19029 ZL006 1181226-02-7 ZL006 is a potent inhibitor of nNOS/PSD-95 interaction, and inhibits NMDA receptor-mediated NO synthesis.
CSN14855 Verminoside 50932-19-9 Verminoside, a natural product isolated and purified from the barks of Kigelia pinnata with anti-inflammatory effect, inhibits both iNOS expression and NO release in the LPS-induced J774.A1 macrophage cell line.
CSN23846 Tetrahydrobiopterin 17528-72-2 Tetrahydrobiopterin is a cofactor of the aromatic amino acid hydroxylases enzymes and also acts as an essential cofactor for all nitric oxide synthase (NOS) isoforms.
CSN25207 SDMA 30344-00-4 SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity.
CSN26150 S-Methyl-L-thiocitrulline 209589-59-3 S-Methyl-L-thiocitrulline (Me-TC) is a potent NOS inhibitor. It inhibited the oxidation of L-arginine and the L-arginine-independent oxidation of NADPH by nNOS from human brain.
CSN33112 Ronopterin 206885-38-3 Ronopterin is a potent Nitric oxide synthase inhibitor.
CSN22647 Piperidin-2-imine hydrochloride 16011-96-4 Piperidin-2-imine HCl is a selective iNOS inhibitor.
CSN25404 L-NNA 2149-70-4 Nitroarginine, or Nω-nitro-L-arginine, is a nitro derivative of the amino acid arginine. It is an inhibitor of nitric oxide synthase and hence a vaso-constrictor and coronary constrictor. As such, it finds widespread use as a biochemical tool in the study of nitric oxide and its biological effects. Nitroarginine has been used in research studying coronary constriction, in the presence of midazolam vasodilatation was unaffected by nitroarginine. Nitroarginine is currently in clinical trials for treating patients with advanced solid tumors.
CSN21155 L-NMMA acetate 53308-83-1 L-NMMA acetate is a nitric oxide synthase inhibitor of all NOS isoforms including NOS1, NOS2, and NOS3. The Ki values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 µM, respectively.
CSN22944 L-NIO dihydrochloride 159190-44-0 L-NIO 2HCl is an inhibitor of nitric oxide (NO) synthase, including iNOS, eNOS and nNOS.
CSN22943 L-NIL hydrochloride 150403-89-7 L-NIL HCl is a selective inhibitor of inducible nitric oxide synthase with IC50 of 3.3 μM.
CSN16603 L-NAME hydrochloride 51298-62-5 L-NAME HCl is a non-selective NOS inhibitor with Ki values of 15 nM, 39 nM and 4.4 μM for nNOS (bovine), eNOS (human), and iNOS (murine), respectively.
CSN22880 L-Canavanine sulfate 2219-31-0 L-Canavanine Sulfate is a NO synthase inhibitor.
CSN15716 L-Arginine hydrochloride 1119-34-2 L-Arginine HCl is a substrate of NOS and a nonessential amino acid in human.
CSN22080 Kuwanon A 62949-77-3 Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.) and inhibits nitric oxide production with IC50 of 10.5 μM.
CSN19956 Irisflorentin 41743-73-1 Irisflorentin, a natural product isolated and purified from the rhizomes of Belamcanda chinensis (L.) DC., has anti-inflammatory mechanism in LPS-activated RAW 264.7 macrophages, by reducing the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO.
CSN16369 Imperatorin 482-44-0 Imperatorin is a naturally occuring multiple-target inhibitor of NOS with IC50 value of 9.2 μM, BChE with IC50 value of 31.4 μM, a potent calcium antagonist on vascular smooth muscle. It is also a weak agonist of TRPV1 with EC50 of 12.6±3.2 μM.
CSN19030 IC87201 866927-10-8 IC87201, an inhibitor of PSD95-nNOS protein-protein interactions, suppresses NMDAR-dependent NO and cGMP formation.
CSN18103 GW274150 210354-22-6 GW274150 is an arginine-competitive, NADPH-dependent iNOS inhibitor that has been identified from a series of acetamide amino acids that have a high selectivity for iNOS vs both eNOS (> 260-fold) and nNOS (> 219-fold) and high bioavailability (> 90%) after oral administration.
CSN22917 Gadolinium(III) chloride hexahydrate 13450-84-5 Gadolinium(III) chloride hexahydrate can inhibit macrophages and significantly decrease NO production and inducible INOS expression in rat lung macrophages.
CSN22803 EIT Hydrobromide 1071-37-0 EIT Hydrobromide is a potent, selective and reversible inhibitor of isoform II NO synthase with IC50 of 13 nM.
CSN22730 BYK 191023 2HCl 1216722-25-6 BYK 191023 2HCl is a potent and selective inhibitor of inducible nitric oxide synthase (iNOS) with IC50 of 86 nM.
CSN27536 Asymmetric dimethylarginine 30315-93-6 Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a number of pathological states.
CSN22685 AR-C102222 hydrochloride 1781934-50-6 AR-C 102222 is a selective iNOS inhibitor with IC50 of 0.037 μM.
CSN22682 AMT hydrochloride 21463-31-0 AMT HCl is a potent, selective and reversible inhibitor of iNOS with IC50 of 3.6 nM.
CSN10284 Aminoguanidine hydrochloride 1937-19-5 Aminoguanidine HCl is a selective and irreversible iNOS inhibitor.
CSN23420 Agmatine sulfate 2482-00-0 Agmatine sulfate is a competitive NOS inhibitor.
CSN23606 7-Nitroindazole 2942-42-9 7-Nitroindazole is a competitive, reversible and non-selective NOS inhibitor.
CSN25443 3-Bromo-7-nitroindazole 74209-34-0 3-Bromo-7-nitroindazole is a more potent and selective inhibitor of neuronal nitric oxide synthase (nNOS) than eNOS or inducible nitric oxide synthase (iNOS). 3-Bromo-7-nitroindazole affects the intercellular messenger nitric oxide (NO) synthesis throughout the body and brain.
CSN12781 2-(2-Aminoethyl)isothiourea dihydrobromide 56-10-0 2-(2-Aminoethyl)isothiourea dihydrobromide inhibits nitric oxide synthase (NOS).
CSN16858 1400W Dihydrochloride 214358-33-5 1400W 2HCl is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase (iNOS).
CSN22638 S-Methylisothiourea sulfate 867-44-7 (S)-Methylisothiourea Sulfate is a highly selective, potent and competitive inhibitor of iNOS.
CSN37025 Cyanidin 3-sambubioside chloride 33012-73-6
CSN51532 2-Amino-6,7-dimethyl-5,6,7,8-tetrahydropteridin-4-ol hydrochloride 945-43-7
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