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NOS
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN19029 | ZL006 | 1181226-02-7 | ZL006 is a potent inhibitor of nNOS/PSD-95 interaction, and inhibits NMDA receptor-mediated NO synthesis. |
| CSN23846 | Tetrahydrobiopterin | 17528-72-2 | Tetrahydrobiopterin is a cofactor of the aromatic amino acid hydroxylases enzymes and also acts as an essential cofactor for all nitric oxide synthase (NOS) isoforms. |
| CSN25207 | SDMA | 30344-00-4 | SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity. |
| CSN22647 | Piperidin-2-imine HCl | 16011-96-4 | Piperidin-2-imine HCl is a selective iNOS inhibitor. |
| CSN25404 | L-NNA | 2149-70-4 | Nitroarginine, or Nω-nitro-L-arginine, is a nitro derivative of the amino acid arginine. It is an inhibitor of nitric oxide synthase and hence a vaso-constrictor and coronary constrictor. As such, it finds widespread use as a biochemical tool in the study of nitric oxide and its biological effects. Nitroarginine has been used in research studying coronary constriction, in the presence of midazolam vasodilatation was unaffected by nitroarginine. Nitroarginine is currently in clinical trials for treating patients with advanced solid tumors. |
| CSN21155 | L-NMMA Acetate | 53308-83-1 | L-NMMA acetate is a nitric oxide synthase inhibitor of all NOS isoforms including NOS1, NOS2, and NOS3. The Ki values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 µM, respectively. |
| CSN16603 | L-NAME HCl | 51298-62-5 | L-NAME HCl is a non-selective NOS inhibitor with Ki values of 15 nM, 39 nM and 4.4 μM for nNOS (bovine), eNOS (human), and iNOS (murine), respectively. |
| CSN15716 | L-Arginine HCl | 1119-34-2 | L-Arginine HCl is a substrate of NOS and a nonessential amino acid in human. |
| CSN22080 | Kuwanon A | 62949-77-3 | Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.) and inhibits nitric oxide production with IC50 of 10.5 μM. |
| CSN16369 | Imperatorin | 482-44-0 | Imperatorin is a naturally occuring multiple-target inhibitor of NOS with IC50 value of 9.2 μM, BChE with IC50 value of 31.4 μM, a potent calcium antagonist on vascular smooth muscle. It is also a weak agonist of TRPV1 with EC50 of 12.6±3.2 μM. |
| CSN22803 | EIT Hydrobromide | 1071-37-0 | EIT Hydrobromide is a potent, selective and reversible inhibitor of isoform II NO synthase with IC50 of 13 nM. |
| CSN27536 | Asymmetric dimethylarginine | 30315-93-6 | Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a number of pathological states. |
| CSN22682 | AMT HCl | 21463-31-0 | AMT HCl is a potent, selective and reversible inhibitor of iNOS with IC50 of 3.6 nM. |
| CSN10284 | Aminoguanidine HCl | 1937-19-5 | Aminoguanidine HCl is a selective and irreversible iNOS inhibitor. |
| CSN23420 | Agmatine sulfate | 2482-00-0 | Agmatine sulfate is a competitive NOS inhibitor. |
| CSN23606 | 7-Nitroindazole | 2942-42-9 | 7-Nitroindazole is a competitive, reversible and non-selective NOS inhibitor. |
| CSN25443 | 3-Bromo-7-nitroindazole | 74209-34-0 | 3-Bromo-7-nitroindazole is a more potent and selective inhibitor of neuronal nitric oxide synthase (nNOS) than eNOS or inducible nitric oxide synthase (iNOS). 3-Bromo-7-nitroindazole affects the intercellular messenger nitric oxide (NO) synthesis throughout the body and brain. |
| CSN16858 | 1400W 2HCl | 214358-33-5 | 1400W 2HCl is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase (iNOS). |
| CSN22638 | (S)-Methylisothiourea Sulfate | 867-44-7 | (S)-Methylisothiourea Sulfate is a highly selective, potent and competitive inhibitor of iNOS. |