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Notch
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN27582 | RIN1 | N/A | RIN1 is a new class of small molecule inhibitor that disrupts the interaction between NOTCH and RBPJ. It also blocked the functional interaction of RBPJ with SHARP, a scaffold protein that forms a transcriptional repressor complex with RBPJ in the absence of NOTCH signaling. |
| CSN18826 | IMR-1A | 331862-41-0 | IMR-1A is the metabolite of IMR-1, a Notch inhibitor targeting the transcriptional activation. |
| CSN18825 | IMR-1 | 310456-65-6 | IMR-1 is a cell penetrant and potent inhibitor of Notch transcriptional activation complex with IC50 of 6 μM for targeting the transcriptional activation. |
| CSN18205 | FLI-06 | 313967-18-9 | FLI-06 is a Notch signaling inhibitor with EC50 of 2.3 μM which can disrupt Notch trafficking and processing. |