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Nrf2

Nrf2

货号 产品名 CAS号 信息
CSN12060 2-(tert-Butyl)benzene-1,4-diol(may occur to produce black solid) 1948-33-0 TBHQ is a synthetic aromatic organic compound used as an antioxidant and preservative.
CSN17891 Omaveloxolone 1474034-05-3 RTA-408 is a synthetic triterpenoid that potently activates the antioxidative transcription factor Nrf2 by binding KEAP1 and inhibits the proinflammatory transcription factor NF-κB.
CSN23062 RA839 1832713-02-6 RA-839 is a noncovalent small molecule binder to Keap1 and selective activator of Nrf2 signaling. RA-839 also suppresses LPS-induced iNOS and nitric oxide expression in macrophages.
CSN23142 TAT-14 1362661-34-4 Nrf2 pathway activator; blocks Nrf2/Keap1 interaction
CSN19067 1-(5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl)-3-(pyridin-2-ylmethyl)urea 1414963-82-8 NK-252 is a Nrf2 activator, exhibits a greater Nrf2-activating potential than OPZ.
CSN22981 (E)-4-methoxy-4-oxobut-2-enoic acid 2756-87-8 MMF can induce Nrf2 activation.
CSN22320 ML385 846557-71-9 ML-385 is a selective inhibitor of NRF2 via binding to Neh1 DNA binding domain with IC50 of 1.9 µM.
CSN21243 KI696 1799974-70-1 KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction.
CSN22428 Hesperin 4430-35-7 Hesperin is a bioactive ingredient present in Japanese horseradish (wasabi) and has been shown to be an Nrf2 activator.
CSN17434 Ginsenoside Rh3 105558-26-7 Ginsenoside Rh3, a natural product isolated and purified from the roots of Panax ginseng C.
CSN10136 Farrerol 24211-30-1 Farrerol is a natural product isolated and purified from the leaves of Rhododendron dauricum L.
CSN29518 Ezetimibe ketone 191330-56-0 Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. Ezetimibe is a potent cholesterol absorption inhibitor.Ezetimibe ketone (EZM-K) is a phase-I metabolite of Ezetimibe.
CSN13701 Dimethyl fumarate 624-49-7 Dimethyl fumarate is a nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator which induces upregulation of antioxidant gene expression.
CSN18597 CDDO-EA 932730-51-3 CDDO-EA is an activator of Nrf2/ARE with neuroprotective effect.
CSN19355 AKBA 67416-61-9 AKBA is a novel Nrf2 activator which can increase basal and UVA-induced levels of Nrf2.
CSN25689 AI-3 882288-28-0 AI-3 is an antivator of antioxidant response element (ARE). It can disrupt Nrf2/Keap1 and Keap1/Cul3 interactions and stabilize Nrf2.
CSN23667 4-Octyl Itaconate 3133-16-2 4-Octyl itaconate is the endogenous metabolite of itaconate with anti-inflammatory activity. It can decrease cytokine production and protect against lipopolysaccharide-induced lethality in vivo.
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