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货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN22262 | VH032 | 1448188-62-2 | VH-032 (VHL ligand 1) is a VHL ligand for PROTAC and potent, small molecule inhibitor of the VHL/HIF-1α interaction with Kd of 185 nM. |
CSN22297 | Gefitinib-based PROTAC 3 | 2230821-27-7 | Gefitinib-based PROTAC 3 is a VHL-recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11.7 nM and 22.3 nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R). |
CSN23768 | PROTAC ERRα ligand 1 | 1264754-13-3 | E3 ligase Ligand 5 is a ligand of E3 ligase, extracted from patent US 20160058872A1, Paragraph 0515. |
CSN22288 | CCT367766 | 2229856-58-8 | CCT-367766 (CCT367766) is a heterobifunctional PROTAC that binds and degrades the putative transcription factor regulator Pirin in cells. |
CSN22261 | (S,R,S)-AHPC-Boc | 1448189-98-7 | A VHL ligand for PROTAC. |
CSN22279 | N3-PEG3-CH2COOH | 172531-37-2 | A PEG3 linker for PROTAC. |
CSN22278 | Azido-PEG2-CH2COOH | 882518-90-3 | A PEG2 linker for PROTAC. |
CSN22276 | PEG6-(CH2CO2H)2 | 77855-76-6 | A PEG linker for PROTAC. |
CSN22260 | HOOCCH2O-PEG4-CH2COOH | 77855-75-5 | A PEG linker for PROTAC. |
CSN25475 | 5-Ethynyl-2'-deoxyuridine | 61135-33-9 | 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker. |
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