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PAFR
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN22535 | YM-264 | 131888-54-5 | YM-264 is a selective, potent and orally active platelet-activating factor (PAF) antagonist with a pKi value of 8.85 for rabbit platelet membranes. |
| CSN14378 | Yangambin | 13060-14-5 | Yangambin, a natural product isolated and purified from the leaves of Ocotea duckei Vattimo., is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF) and therefore constitutes a potential therapeutic agent in different shock states where abnormal PAF release is supposed to play an important role. |
| CSN21880 | Tulopafant | 116289-53-3 | Tulopafant is a platelet activating factor (PAF) antagonist. |
| CSN24298 | TCV-309 | 131311-25-6 | TCV-309 is a PAFR (platelet-activating factor receptor) antagonist. |
| CSN19121 | TCV-309 chloride | 121494-09-5 | TCV-309 chloride is a platelet activating factor (PAF) antagonist. |
| CSN26234 | Foropafant | 136468-36-5 | SR 27417 is a long-acting, highly potent, specific competitive platelet-activating factor (PAF) receptor antagonist with a Ki value of 57 pM for [3H]PAF binding. Foropafant potently inhibits PAF-induced aggregation of rabbit and human platelets. |
| CSN22030 | (R,R)-Secoisolariciresinol diglucoside | 158932-33-3 | Secoisolariciresinol diglucoside is an antagonist of platelet activating factor-receptor and used as an antioxidant. |
| CSN25659 | SDZ-62-434 | 115621-95-9 | SDZ 62-434 is a PAF antagonist which showed strong antiproliferative activity (2-40μM)after 24, 48, and 72h of incubation in CCL-121, CCL-218 and HTB-38 cell lines. |
| CSN21926 | Rupatadine Fumarate | 1217234-48-4 | Rupatadine Fumarate is a dual antagonist of histamine H1 and platelet-activating factor receptors. |
| CSN19864 | C16-PAF | 74389-68-7 | PAF (C16) is an endogenous platelet-activating factor (PAF) and ligand for PAF receptors. |
| CSN14342 | Niranthin | 50656-77-4 | Niranthin, a natural product isolated and purified from the herbs of Phyllanthus amarus, exhibits anti-hepatitis B virus activity both in vitro and in vivo, and antiinflammatory and antiallodynic actions which are probably mediated through its direct antagonistic action on the PAF receptor binding sites. |
| CSN20856 | Ginkgolide K | 153355-70-5 | Ginkgolide K is a novel naturally small molecule compound isolated from Ginkgo biloba and also acts as a PAF antagonist with potential neuroprotection activity. |
| CSN12569 | (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione | 15291-77-7 | Ginkgolide B, an important active terpenoid from Ginkgo biloba leaves, a PAFR antagonist with IC50 of 3.6 μM, is reported to increase cell viability and decrease cell apoptosis. |
| CSN22388 | (S)-(6-(2-Chlorophenyl)-1,4-dimethyl-7,10-dihydro-4H-pyrido[4',3':4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-9(8H)-yl)(cyclopropyl)methanone | 131614-02-3 | E-6123 is a platelet-activating factor (PAF) receptor antagonist. |
| CSN22010 | 48740 RP | 93363-11-2 | 48740 RP (RP-55778) is a platelet-activating factor (PAF) antagonist. |
