400-920-2911
上海市杨浦区翔殷路128号1号楼101
PDK is a kinase enzyme which acts to inactivate the enzyme pyruvate dehydrogenase by phosphorylating it using ATP.
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN17521 | PS48 | 1180676-32-7 | PS48 is a phosphoinositide-dependent protein kinase-1 (PDK1) activator with Kd value of 10.3 μM and binds exclusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site. |
| CSN25617 | PDK-4 Inhibitor compound 8c HCl | 2310262-11-2 | PDK-4 Inhibitor compound 8c HCl is an allosteric PDK-4 inhibitor with IC50 value of 84nM. |
| CSN27211 | JX06 | 729-46-4 | JX06 is a selective covalent PDK1 inhibitor with IC50 values of 49, 101 and 313nM for PDK-1, PDK-2 and PDK-3, respectively. |
| CSN17589 | GSK2334470 | 1227911-45-6 | GSK2334470 is a PDK1 inhibitor with IC50 of ~10 nM, with no activity at other close related AGC-kinases. |