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PERK

PERK

货号 产品名 CAS号 信息
CSN20416 ISRIB 548470-11-7 trans-ISRIB is an Integrated Stress Response Inhibitor. trans-ISRIB inhibits the eIF2α phosphorylation-mediated unfolded protein response following induction of ER stress (IC50 = 5 nM in a cell-reporter assay).
CSN11888 Salubrinal 405060-95-9 Salubrinal is a selective inhibitor of eukaryotic translation initiation factor 2 subunit α (eIF2α) dephosphorylation.
CSN17942 N,N'-(trans-cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)acetamide) 1597403-47-8 ISRIB is a potent inhibitor of PERK signaling showing inhibition of the ATF4 luciferase reporter in HEK293T cells with IC50 of 5 nM.
CSN15812 GSK2656157 1337532-29-2 GSK2656157 is an ATP-competitive inhibitor of PERK enzyme activity with an IC(50) of 0.9 nM and is highly selective for PERK with IC50 values > 100 nM against a panel of 300 kinases.
CSN15902 GSK2606414 1337531-36-8 GSK2606414 is an orally available, potent, and selective PERK inhibitor with an IC50 of 0.4 nM.
CSN15903 1-(5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-fluoro-5-(trifluoromethyl)phenyl)ethan-1-one 1337531-89-1 GSK PERK inhibitor is a biochemical for proteomics research.
CSC20416 ISRIB 548470-11-7
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