Protein Kinase RNA-like Endoplasmic Reticulum Kinase

PERK

PERK
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货号	产品名	CAS号	信息
CSN20416	ISRIB	548470-11-7	trans-ISRIB is an Integrated Stress Response Inhibitor. trans-ISRIB inhibits the eIF2α phosphorylation-mediated unfolded protein response following induction of ER stress (IC50 = 5 nM in a cell-reporter assay).
CSN11888	Salubrinal	405060-95-9	Salubrinal is a selective inhibitor of eukaryotic translation initiation factor 2 subunit α (eIF2α) dephosphorylation.
CSN17942	ISRIB (trans-isomer)	1597403-47-8	ISRIB is a potent inhibitor of PERK signaling showing inhibition of the ATF4 luciferase reporter in HEK293T cells with IC50 of 5 nM.
CSN15812	GSK2656157	1337532-29-2	GSK2656157 is an ATP-competitive inhibitor of PERK enzyme activity with an IC(50) of 0.9 nM and is highly selective for PERK with IC50 values > 100 nM against a panel of 300 kinases.
CSN15902	GSK2606414	1337531-36-8	GSK2606414 is an orally available, potent, and selective PERK inhibitor with an IC50 of 0.4 nM.
CSN15903	PERK-IN-4	1337531-89-1	GSK PERK inhibitor is a biochemical for proteomics research.
CSC20416	ISRIB	548470-11-7