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Phenols

Phenols

货号 产品名 CAS号 信息
CSN20492 Urolithin A 1143-70-0 Urolithin A is a metabolite of ellagitannin with antiproliferative and antioxidant properties. It can cross the blood brain barrier, and may have neuroprotective effects against Alzheimer’s Disease.
CSN13133 Thymol 89-83-8 Thymol, a natural product isolated and purified from the herbs of Thymus serpyllum L., is a positive allosteric modulator of human GABAA receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster.
CSN19746 Rottlerin 82-08-6 Rottlerin, a principal phenolic compound isolated and purified from Kamala plant Mallotus philippinensis, exers its tumour-suppressive function in ACC.
CSN19968 Rhaponticin 155-58-8 Rhapontin is a natural product isolated and purified from the roots of Rhei Rhizoma.
CSN12332 Rhapontigenin 500-65-2 Rhapontigenin, a natural product isolated and purified from the rhizomes of Rheum undulatum with antioxidative, antihyperlipidemic, and antifungal activities, inhibits tyrosinase activity and melanin synthesis in B16F10 melanoma cells and HIF-1α accumulation and angiogenesis in PC-3 prostate cancer cells, suppresses breast cancer cell migration and invasion, which is involved in inhibiting the PI3K-dependent Rac1 signaling pathway.
CSN16007 Punicalagin 65995-63-3 Punicalagin, a natural product isolated and purified from the peel of Punica granatum L., is a potential alternative or supplemental agent for prevention of Salmonella infection, has a greater antifungal activity against T.
CSN23597 Phloretic acid 501-97-3 Phloretic Acid can defense influenza through augmentation of type I interferon signaling, it's a microbially associated metabolite and a naturally occurring phenolic compound.
CSN14672 Moracin P 102841-46-3 Moracin P, a natural product isolated and purified from the root bark of Morus alba L., shows significant nitric oxide (NO) production inhibitory effects in RAW264.7 cells, exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia, and might protect neuronal cell death against the oxidative stress induced by oxygen-glucose deprivation(OGD), can enhance cell viability in dose-dependent manner against OGD-induced cell death in neuroblastoma SH-SY5Y cells.
CSN12887 Methyl Orsellinate 3187-58-4 Methyl orsellinate, a natural product isolated and purified from the herbs of Dianella ensifolia (L.) DC, exhibits no detectable antiproliferative activity whereas the trimeric tenuiorin caused moderate/weak reduction in [3H]-thymidine uptake of the pancreatic- and colon cancer cells, with ED50 values of 87.9 and 98.3 mM respectively, and inhibits PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 mM.
CSN12887 Methyl Orsellinate 3187-58-4 Methyl orsellinate, a natural product isolated and purified from the herbs of Dianella ensifolia (L.) DC, exhibits no detectable antiproliferative activity whereas the trimeric tenuiorin caused moderate/weak reduction in [3H]-thymidine uptake of the pancreatic- and colon cancer cells, with ED50 values of 87.9 and 98.3 mM respectively, and inhibits PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 mM.
CSN12840 Isovanicaline 621-59-0 Isovanicaline, a natural product isolated and purified from the barks of Pinus yunnanensis, is a selective inhibitor of aldehyde oxidase, is metabolized by aldehyde dehydrogenase into isovanillic acid ,and the LD50 (rat, ipr) is 1276 mg/kg.
CSN21209 Hispidin 555-55-5 Hispidin is a polyphenol originally isolated from P. hispidus that has diverse biological activities, including antioxidant, anti-inflammatory, and cytoprotective properties.
CSN14412 Hirsutenone 41137-87-5 Hirsutenone, a natural product isolated and purified from the eaves of Alnus nepalensis, exhibits anti-cancer effect against prostate cancer through a direct physical inhibition of Akt1/2, attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity, and may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. Hirsutenone showed potent PL(pro) inhibitory activity with IC50 value of 4.1µM.
CSN20010 Hinokitiol 499-44-5 Hinokitiol, an iron chelator originally extracted from woods of Thuja plicata and Chamaecyparis obtuse, has been found to inhibit ultraviolet B-induced apoptosis in keratinocytes of murine ear skin via antioxidant activity of metallothionein. It can partially mimic the function of missing protein transporters of iron, and possibly other ions, may have potential in treating human diseases.
CSN14065 Goniothalamin 17303-67-2 Goniothalamin, a natural product isolated and purified from the herbs of Goniothalamus griffithii, enhances rather than inhibits the ATPase activity of a cyanobacterial Hsp90 (HtpG) and a yeast Hsp90, increases both K(m) and k(cat) of the Hsp90s.
CSN11097 Ginkgolic Acid 22910-60-7 Ginkgolic acid is a natural product isolated and purified from the leaves of Ginkgo biloba L.with suspected cytotoxic, allergenic, mutagenic and carcinogenic properties.
CSN17019 Gentisic Acid 490-79-9 Gentisic acid is a natural product isolated and purified from the roots of Gentiana scabra Bunge.
CSN23327 Ethyl Vanillate 617-05-0 Ethyl Vanillate is a flavouring agent exhibits strong antioxidant activity, it's a vanillin analog, also used in the food industry.
CSN16055 Ethyl 2,4,6-Trihydroxybenzoate 90536-74-6 Ethyl 2,4,6-trihydroxybenzoate, a natural product isolated and purified from the herbs of Celtis biondii, suppresses cellular cholesterol accumulation in a dose-dependent manner and induces the transcriptional activation of LXR-α/-β-responsive genes, and is a dual-LXR modulator that regulates the expression of key genes in cholesterol homeostasis in multiple cells without inducing lipid accumulation in HepG2 cells.
CSN19779 Dihydropinosylvin 14531-52-3 Dihydropinosylvin, is a natural product isolated and purified from the herbs of Dioscorea rotundata with anti-fungal activity.
CSN19341 Desoxyrhaponticin 30197-14-9 Desoxyrhaponticin, a natural product isolated and purified from the roots of Rumex obtusifolius L., is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney, and is considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells.
CSN19341 Desoxyrhaponticin 30197-14-9 Desoxyrhaponticin, a natural product isolated and purified from the roots of Rumex obtusifolius L., is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney, and is considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells.
CSN20557 Artepillin C 72944-19-5 Artepillin C is a major, biologically active ingredient of Brazilian propolis, possesses anticancer activity against several cancer cells with different tissue origins.
CSN14397 alpha-Viniferin 62218-13-7 alpha-Viniferin, a natural product isolated and purified from the herb of Carex humilis Leyss., a specific, reversible and noncompetitive AChE inhibitor (IC50 = 2.0 mM), exhibits a dose-dependent inhibition on cyclooxygenase activity, where 50% of inhibition (IC50) was shown at a final concentration of about 7 mM, and has anti-inflammatory activity, down-regulating STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages.
CSN19893 Alnustone 33457-62-4 Alnustone is a natural product isolated and purified from the seeds of Alpinia katsumadai Hayata exerting significant anti-inflammatory activity in the assay of carrageenin-induced hind paw edema in rats.
CSN23296 Acetosyringone 2478-38-8 Acetosyringone is a phenolic natural product secreted by wounded plant tissues, is widely used to increase efficacy of genetic transformation for the creation of genetically modified dicotyledonous and monocotyledonous plants.
CSN19961 8-Gingerol 23513-08-8 8-Gingerol, a natural product isolated and purified from the rhizome of Zingiber officinale Roscoe.
CSN19518 4-Hydroxybenzoic Acid 99-96-7 4-Hydroxybenzoic acid, a natural product isolated and purified from the herbs of Rhodiola crenulata, positively regulates the expression of gum cluster to promote EPS production in PXO99A, and its derivatives have potential to as pan-HDAC inhibitors with anticancer properties.
CSN23480 4-Ethylphenol 123-07-9 4-Ethylphenol is also known as 4-EP which is a para-substituted phenolic compound found in red wine.
CSN14127 3,8-Di-O-Methylellagic Acid 2239-88-5 3,8-Di-O-methylellagic acid, a natural product isolated and purified from the peels of Punica granatum L.
CSN19888 3,4-Dihydroxybenzaldehyde 139-85-5 3,4-dihydroxybenzaldehyde, a natural product isolated and purified from the heartwood of Cassia garrettiana, can scavenge DPPH radical, hydroxyl radical and intracellular ROS.
CSN22068 2-Ethyl-5-methylphenol 1687-61-2 2-Ethyl-5-methylphenol is a constituent of Angelica species, it is a metabolite of Penicillium species on barley.
CSN23586 2',5'-Dihydroxyacetophenone 490-78-8 2',5'-Dihydroxyacetophenone is a mixture of various isomers of adihydroxyacetophenone which is used as a flavoring agent.
CSN14428 11-O-Galloylbergenin 82958-44-9 11-O-Galloylbergenin, a natural product isolated and purified from the aerial parts of Bergenia ligulata., shows significant analgesic activity at doses of 20 and 40 mg/kg against formalin test in rats, and exhibits significant anti-inflammatory activity in carrageenan-induced paw edema model at doses of 10, 20 and 30 mg/kg.
CSN19891 10-Gingerol 23513-15-7 10-Gingerol, a natural product isolated and purified from the rhizomes of Zingiber officinale Roscoe.
CSN19970 Curculigoside 85643-19-2
CSN19970 Curculigoside 85643-19-2
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