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Phenols
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN10043 | (rel)-β-Tocopherol | 148-03-8 | β-tocopherol is one of the naturally occurring forms of Vitamin E and is biologically less active than α-Tocopherol. |
CSN15878 | Urolithin B | 1139-83-9 | Urolithin B is a natural product with anti-proliferative and antioxidant activity, which can penetrate the blood-brain barrier and may have neuroprotective effects against Alzheimer’s Disease.It inhibits aromatase activity in human placental microsomes and aromatase-sensitive MCF-7 (MCF-7aro) human breast cancer cells when used at concentrations of 47 and 4.7 µM, respectively. |
CSN14417 | Torachrysone | 22649-04-3 | Torachrysone, a natural product isolated and purified from the seeds of Cassia obtusifolia, shows promising antioxidant activity and noticeable antibacterial effects on four strains of methicillin-resistant Staphylococcus aureus with a minimum inhibitory concentration of 2-64 mg/mL. |
CSN13133 | 2-Isopropyl-5-methylphenol | 89-83-8 | Thymol, a natural product isolated and purified from the herbs of Thymus serpyllum L., is a positive allosteric modulator of human GABAA receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster. |
CSN17210 | (2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-(4-hydroxyphenethoxy)tetrahydro-2H-pyran-3,4,5-triol | 10338-51-9 | Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata. |
CSN16007 | Punicalagin | 65995-63-3 | Punicalagin, a natural product isolated and purified from the peel of Punica granatum L., is a potential alternative or supplemental agent for prevention of Salmonella infection, has a greater antifungal activity against T. |
CSN19413 | (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol | 27208-80-6 | Polydatin, extracted from the roots ofPolygonum cuspidatumSieb, a widely used traditional Chinese remedies, possesses anti-inflammatory activity in several experimental models. |
CSN15473 | Perilloxin | 263249-77-0 | Perilloxin, a natural product isolated and purified from the stems of Perilla frutescens var. acuta., possesses inhibitory activities against cyclooxygenase-1,with IC(50) values of 23.2 mM. |
CSN18175 | Paradol | 27113-22-0 | Paradol is an effective inhibitor of tumor promotion in mouse skin carcinogenesis, binds to cyclooxygenase (COX)-2 active site, it's a pungent phenolic substance isolated and purified from ginger and other Zingiberaceae plants. |
CSN19396 | (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid | 24280-93-1 | Mycophenolic Acid is an an immunosuppresant agent with a potent inibition of IMPDH (inosine monophosphate dehydrogenase) and potent anti-proliferative activity, it can be isolated from several Penicillium species. |
CSN15165 | Mulberrofuran H | 89199-99-5 | Mulberrofuran H exhibits potent antifungal activity against phytopathogenic fungi Colletotrichum orbiculare, Phytophthora capsici, Corynespora cassiicola and Fusarium oxysporum. |
CSN14672 | Moracin P | 102841-46-3 | Moracin P, a natural product isolated and purified from the root bark of Morus alba L., shows significant nitric oxide (NO) production inhibitory effects in RAW264.7 cells, exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia, and might protect neuronal cell death against the oxidative stress induced by oxygen-glucose deprivation(OGD), can enhance cell viability in dose-dependent manner against OGD-induced cell death in neuroblastoma SH-SY5Y cells. |
CSN15161 | Moracin C | 69120-06-5 | Moracin C, a natural product isolated and purified from the root bark of Morus alba L., is a potent antibacterial compound which inhibits FabI and fatty acid synthesis. |
CSN12887 | Methyl 2,4-dihydroxy-6-methylbenzoate | 3187-58-4 | Methyl orsellinate, a natural product isolated and purified from the herbs of Dianella ensifolia (L.) DC, exhibits no detectable antiproliferative activity whereas the trimeric tenuiorin caused moderate/weak reduction in [3H]-thymidine uptake of the pancreatic- and colon cancer cells, with ED50 values of 87.9 and 98.3 mM respectively, and inhibits PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 mM. |
CSN12887 | Methyl 2,4-dihydroxy-6-methylbenzoate | 3187-58-4 | Methyl orsellinate, a natural product isolated and purified from the herbs of Dianella ensifolia (L.) DC, exhibits no detectable antiproliferative activity whereas the trimeric tenuiorin caused moderate/weak reduction in [3H]-thymidine uptake of the pancreatic- and colon cancer cells, with ED50 values of 87.9 and 98.3 mM respectively, and inhibits PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 mM. |
CSN12840 | 3-Hydroxy-4-Methoxybenzaldehyde | 621-59-0 | Isovanicaline, a natural product isolated and purified from the barks of Pinus yunnanensis, is a selective inhibitor of aldehyde oxidase, is metabolized by aldehyde dehydrogenase into isovanillic acid ,and the LD50 (rat, ipr) is 1276 mg/kg. |
CSN14412 | Hirsutenone | 41137-87-5 | Hirsutenone, a natural product isolated and purified from the eaves of Alnus nepalensis, exhibits anti-cancer effect against prostate cancer through a direct physical inhibition of Akt1/2, attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity, and may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. Hirsutenone showed potent PL(pro) inhibitory activity with IC50 value of 4.1µM. |
CSN20010 | 2-Hydroxy-4-isopropylcyclohepta-2,4,6-trien-1-one | 499-44-5 | Hinokitiol, an iron chelator originally extracted from woods of Thuja plicata and Chamaecyparis obtuse, has been found to inhibit ultraviolet B-induced apoptosis in keratinocytes of murine ear skin via antioxidant activity of metallothionein. It can partially mimic the function of missing protein transporters of iron, and possibly other ions, may have potential in treating human diseases. |
CSN16502 | Guaiacol | 90-05-1 | Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is readily oxidized by the heme iron of peroxidases including the peroxidase of cyclooxygenase (COX) enzymes. |
CSN11097 | Ginkgolic Acid | 22910-60-7 | Ginkgolic acid is a natural product isolated and purified from the leaves of Ginkgo biloba L.with suspected cytotoxic, allergenic, mutagenic and carcinogenic properties. |
CSN11098 | Ginkgolic Acid (C13:0) | 20261-38-5 | Ginkgolic Acid C13:0 is a natural product with wide antimicrobial spectrum. |
CSN17019 | 2,5-Dihydroxybenzoic Acid | 490-79-9 | Gentisic acid is a natural product isolated and purified from the roots of Gentiana scabra Bunge. |
CSN15170 | Gancaonin I | 126716-36-7 | Gancaonin I is a natural product isolated and purified from the roots of Glycyrrhiza glabra with anti-BsFtsZ GTPase activities and significant inhibitory activity against B. subtilis, with a MIC value of 5 uM. |
CSN15859 | Ethyl 4-hydroxybenzoate | 120-47-8 | Ethylparaben, a natural product isolated and purified from the male melon fly Dacus cucurbitae, is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative. |
CSN16055 | Ethyl 2,4,6-Trihydroxybenzoate | 90536-74-6 | Ethyl 2,4,6-trihydroxybenzoate, a natural product isolated and purified from the herbs of Celtis biondii, suppresses cellular cholesterol accumulation in a dose-dependent manner and induces the transcriptional activation of LXR-α/-β-responsive genes, and is a dual-LXR modulator that regulates the expression of key genes in cholesterol homeostasis in multiple cells without inducing lipid accumulation in HepG2 cells. |
CSN15159 | Ducheside A | 176665-78-4 | Ducheside A has anti-fungal activity. |
CSN19341 | Desoxyrhaponticin | 30197-14-9 | Desoxyrhaponticin, a natural product isolated and purified from the roots of Rumex obtusifolius L., is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney, and is considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells. |
CSN19341 | Desoxyrhaponticin | 30197-14-9 | Desoxyrhaponticin, a natural product isolated and purified from the roots of Rumex obtusifolius L., is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney, and is considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells. |
CSN20998 | Dehydropachymic acid | 77012-31-8 | Dehydropachymic acid is extracted from the root of wolfiporia cocos (Schw.) Ryv. with antiinflammatory activity. |
CSN20998 | Dehydropachymic acid | 77012-31-8 | Dehydropachymic acid is extracted from the root of wolfiporia cocos (Schw.) Ryv. with antiinflammatory activity. |
CSN20998 | Dehydropachymic acid | 77012-31-8 | Dehydropachymic acid is extracted from the root of wolfiporia cocos (Schw.) Ryv. with antiinflammatory activity. |
CSN20998 | Dehydropachymic acid | 77012-31-8 | Dehydropachymic acid is extracted from the root of wolfiporia cocos (Schw.) Ryv. with antiinflammatory activity. |
CSN19424 | (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione | 458-37-7 | Curcumin is a natural phenolic compound with impressive antioxidant properties. |
CSN16343 | 2,4,5-Trimethoxybenzaldehyde | 4460-86-0 | Asaronaldehyde is a COX-2 inhibitor, exhibiting 17-fold selectivity over COX-1, it's a natural product isolated and purified from the rhizoma of Acorus tatarinowii Schott. |
CSN20557 | Artepillin C | 72944-19-5 | Artepillin C is a major, biologically active ingredient of Brazilian propolis, possesses anticancer activity against several cancer cells with different tissue origins. |
CSN19347 | Alternariol | 641-38-3 | Alternariol is a mycotoxin, topoisomerase I and II inhibitor and potential ER agonist found in Alternaria. |
CSN14397 | α-Viniferin | 62218-13-7 | alpha-Viniferin, a natural product isolated and purified from the herb of Carex humilis Leyss., a specific, reversible and noncompetitive AChE inhibitor (IC50 = 2.0 mM), exhibits a dose-dependent inhibition on cyclooxygenase activity, where 50% of inhibition (IC50) was shown at a final concentration of about 7 mM, and has anti-inflammatory activity, down-regulating STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages. |
CSN19942 | Agrimol B | 55576-66-4 | Agrimol B is a natural product isolated and purified from the herbs of Agrimonia pilosa Ledeb. |
CSN19939 | [8]-Shogaol | 36700-45-5 | 8-Shogaol, a natural product isolated and purified from the rhizomes of Zingber officinale Rosc., can induce apoptosis in a time- and concentration-dependent manner by reactive oxygen species production and depletion of glutathione in HL-60 cells. |
CSN19518 | 4-Hydroxybenzoic acid | 99-96-7 | 4-Hydroxybenzoic acid, a natural product isolated and purified from the herbs of Rhodiola crenulata, positively regulates the expression of gum cluster to promote EPS production in PXO99A, and its derivatives have potential to as pan-HDAC inhibitors with anticancer properties. |
CSN15174 | 4'-Hydroxy-2-O-methylanigorufone | 204134-70-3 | 4'Hydroxy-2-O-methylanigorufone is a natural phytoalexin isolated and purified from the peels of unripe Musa acuminata [AAA] cv. Buñgulan fruit showing a strong α-glucosidase inhibitory effect. |
CSN19517 | 4'-Hydroxyacetophenone | 99-93-4 | 4'-Hydroxyacetophenone, a natural product isolated and purified from the herbs of Rhodiola crenulata, is a potent xanthine oxidase inhibitor. |
CSN18711 | 3,4-Dimethoxybenzoic acid | 93-07-2 | 3,4-Dimethoxybenzoic acid is a natural product isolated and purified from the fruits of Phyllanthus emblica L.. |
CSN22068 | 2-Ethyl-5-methylphenol | 1687-61-2 | 2-Ethyl-5-methylphenol is a constituent of Angelica species, it is a metabolite of Penicillium species on barley. |
CSN17071 | 2-(3,4-Dihydroxyphenyl)ethanol | 10597-60-1 | 2-(3,4-Dihydroxyphenyl)ethanol is a potent and specific inhibitor of lipoxygenase activities, inhibits platelet 12-LO activity with IC50 of 4.2 mM and PMNL 5-LO activity with IC50 of 13 mM. It's a natural product isolated and purified from the herbs of Canarium album with antioxidant property. |
CSN29062 | Aristolochic acid D | 17413-38-6 |