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Phospholipase
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN23873 | VU0155069 | 1130067-06-9 | VU-0155069 is a selective phospholipase D1 (PLD1) inhibitor with IC50 values of 46 and 933 nM for PLD1 and PLD2 respectively. |
| CSN12192 | Varespladib | 172732-68-2 | Varespladib is a potent and selective human non-pancreatic secretory phospholipase A2 (sPLA) inhibitor with IC50 of 7 nM. |
| CSN26229 | U-73343 | 142878-12-4 | U-73343, an inhibitor of PLC (putative phospholipase C)-dependent processes, is an inactive structural analog of U-73122 and can be used as a negative control. |
| CSN12944 | U-73122 | 112648-68-7 | U-73122 is an inhibitor of phospholipase C, phospholipase A2, and 5-LO(5-lipoxygenase). |
| CSN27559 | trans-Benzylideneacetone | 1896-62-4 | trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant. |
| CSN17463 | SPK-601 | 1096687-52-3 | SPK-601 is a potent phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor and is a useful antimicrobial agent. |
| CSN23724 | N-(p-amylcinnamoyl) Anthranilic Acid | 110683-10-8 | N-(p-amylcinnamoyl) Anthranilic Acid is a PLA2 inhibitor and TRP channel modulator. |
| CSN18844 | ML348 | 899713-86-1 | ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM), Exhibits 14-fold selectivity for LYPLA1 over LYPLA2, Also selective over a panel of ~30 other serine hydrolases. |
| CSN25338 | ML349 | 890819-86-0 | ML 349 is a selective and reversible lysophospholipase 2 (LYPLA2) inhibitor with IC50 of 144 nM. |
| CSN23868 | Quinacrine, Mepacrine | 83-89-6 | Mepacrine is an acridine derivative formerly widely used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It's also an inhibitor of phospholipase A2. |
| CSN11815 | Quinacrine dihydrochloride | 69-05-6 | Mepacrine 2HCl is an acridine-derived yellow dye, previously used in the therapy and prevention of malaria and later as an antiprotozoal and immunomodulatory agent. It's also an inhibitor of phospholipase A2. |
| CSN21819 | Quinacrine hydrochloride hydrate | 6151-30-0 | Mepacrine 2HCl 2H2O is an acridine derivative formerly widely used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It's also an inhibitor of phospholipase A2. |
| CSN27210 | m-3M3FBS | 200933-14-8 | m-3M3FBS is a novel phospholipase C activator. It can be developed as a novel anti-leukemic agent. |
| CSN16514 | FIPI | 939055-18-2 | FIPI is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM) preventing PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. |
| CSN15706 | Darapladib | 356057-34-6 | Darapladib is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.25 nM. |
| CSN10738 | D609 | 83373-60-8 | D609 is a selective competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor (Ki = 6.4 μM) and antiviral and antitumor agent. |
| CSN17598 | CAY10650 | 1233706-88-1 | CAY10650 is a highly potent cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 value of 12 nM. |
| CSN27739 | CAY10594 | 1130067-34-3 | CAY10594 is a selective PLD2 inhibitor with IC50 values of 140nM and 5.1μM for PLD2 and PLD1, respectively. It strongly inhibits the invasive migration of breast cancer cells in transwell assays. |
| CSN27249 | 7,7-Dimethyleicosadienoic Acid | 89560-01-0 | 7,7-Dimethyleicosadienoic Acid is a selective secretory type phospholipase A2 (PLA2) inhibitor with IC50 value of 250μM in the presence of Epo. |
| CSN21980 | 1-Linoleoyl Glycerol | 2277-28-3 | 1-Linoleoyl Glycerol is a fatty acid glycerol that has been isolated from S. chinensis roots and exhibits Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitory activities with IC50 values of 45.0 μM for (R)-1-Linoleoyl Glycerol and 52.0 μM for (S)-1-Linoleoyl Glycerol, respectively. |
| CSN29448 | (R)-Edelfosine | 77286-66-9 | Selective PI-PLC inhibitor, also PAF receptor agonist |
