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PI3K

PI3K

货号 产品名 CAS号 信息
CSN18633 UNBS5162 956590-23-1 UNBS5162 is a naphthalimide and a hydrolysis product of UNBS3157 that decreases CXCL chemokine expression in experimental prostate cancers and the mean antiproliferative activity IC50 value is 17.9 μM for 9 cancer cell lines.
CSN22559 SF2523 1174428-47-7 SF2523 blocks BRD4 binding to MYCN promoter PS1/PS2.
CSN22202 PQR530 1927857-61-1 PQR530 is a potent, oral and brain-penetrant dual pan-PI3K/mTORC1/2 inhibitor, exhibiting antitumor activity.
CSN27247 PIK-75   372196-67-3 PIK-75 is a selective p110α inhibitor with IC50 of 5.8 nM with 200-fold more potently than p110β, and also potently inhibits DNA-PK with IC50 of 2 nM.
CSN22432 IP3K Inhibitor 519178-28-0 IP3K Inhibitor is a IP3K inhibitor with an IC50 of 10.2 μM.
CSN14412 Hirsutenone 41137-87-5 Hirsutenone, a natural product isolated and purified from the eaves of Alnus nepalensis, exhibits anti-cancer effect against prostate cancer through a direct physical inhibition of Akt1/2, attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity, and may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. Hirsutenone showed potent PL(pro) inhibitory activity with IC50 value of 4.1µM.
CSN17784 GNE-317 1394076-92-6 GNE-317 is a potent PI3K/mTOR inhibitor that can cross the blood–brain barrier and shows potent suppression of the PI3K pathway in the brain of mice with intact BBB.
CSN24837 Erucic acid 112-86-7 Erucic acid is a monounsaturated omega-9 fatty acid used as mineral oil and a precursor to biodiesel fuel.
CSN19217 740 Y-P 1236188-16-1 740 Y-P is cell-permeable peptide activator of PI3K.
CSN19389 3-Methyladenine 5142-23-4 3-Methyladenine is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM.
CSN25447 Erucic acid 112-86-7
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