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PI4K
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN33108 | UNC3230 | 1031602-63-7 | UNC3230 is a PIP5K1C inhibitor. It lowered PIP2 levels in DRG neurons and attenuated hypersensitivity when administered intrathecally or into the hindpaw. |
CSN22614 | UCB9608 | 1616413-96-7 | UCB9608 is inhibitor of PI4KIIIβ with IC50 of 11 nM and can improve metabolic stability. It is used as an immunosuppressive agent. |
CSN17170 | PIK-93 | 593960-11-3 | PIK-93 is the potent, synthetic PI4K (PI4KIIIβ) inhibitor with IC50 of 19 nM, and shown to inhibit PI3Kα with IC50 of 39 nM. |
CSN17837 | PI4KIIIbeta-IN-9 | 1429624-84-9 | PI4KIIIbeta-IN-9 is a potent PI4KIIIβ inhibitor (IC50 of 7 nM) and is > 140-fold selective over PI3Kγ and > 20-fold selective over PI3Kδ, and shows no inhibition of vps34 at concentrations up to 20 μM. |
CSN18058 | PI4KIIIbeta-IN-10 | 1881233-39-1 | PI4KIIIbeta-IN-10 is the most potent PI4KIIIβ inhibitor currently reported, with very minor off-target inhibition of PI4KIIIβ related lipid kinases (IC50 = 3.6 nM). |
CSN13171 | PI4KIII beta inhibitor 3 | 1245319-54-3 | PI4KIII beta inhibitor 3 is a high effective PI4KIII beta inhibitor with IC50 of 5.7 nM. |
CSN20595 | PI-273 | 925069-34-7 | PI-273 is a substrate-competitive, specific small molecule inhibitor of PI4KIIα which inhibits the growth of breast cancer cells. |
CSN22970 | MI 14 | 1715934-43-2 | MI 14 is a potent and selective PI 4-K IIIβ inhibitor with IC50 of 54 nM. |
CSN20289 | MDL-860 | 78940-62-2 | MDL-860 is a broad-spectrum anti-picornavirus compound and one of the few promising candidates effective in in vivo virus infection. |
CSN20236 | KDU731 | 1610610-48-4 | KDU731, a cryptosporidium PI(4)K inhibitor, is a drug candidate for cryptosporidiosis. |
CSN20220 | KDU691 | 1513879-19-0 | KDU691 is a plasmodium PI(4)K inhibitor which selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites. |
CSN20018 | ISA-2011B | 1395347-24-6 | ISA-2011B is a PIP5Kα (Phosphatidylinositol-4-phosphate 5-kinase-α) inhibitor. |
CSN24301 | BQR-695 | 1513879-21-4 | BQR695 is a PI4K specific inhibitor with IC50 value of 80nM. |
CSN43154 | UCT943 | 1450666-80-4 |