Phosphatidylmyo-Inositol Mannosides | Epigenetics|JAK/STAT Signaling| CSNpharm

Pim

Pim
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货号	产品名	CAS号	信息
CSN16821	TCS-PIM-1-4a	327033-36-3	TCS-PIM-1-4a is a Pim inhibitor that blocks mTORC1 activity via activation of AMPK and kills a wide range of both myeloid and lymphoid cell lines (with IC50 values ranging from 0.8 to 40 μM).
CSN20347	SMI-16a	587852-28-6	SMI-16a, the PIM1/2 Kinase inhibitor VI, controls the biological activity of PIM1/2. This small molecular inhibitor is primarily used for Phosphorylation & Dephosphorylation applications
CSN17458	Pim1 AKK1-IN-1	1093222-27-5	Pim1 AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively and also inhibits MPSK1 and TNIK.
CSN17786	M-110	1395048-49-3	M-110 is a highly selective inhibitor of PIM kinases and inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 μM, with no activity on normal human peripheral blood mononuclear cells up to 40 μM.
CSN19180	CX-6258 HCl	1353859-00-3	CX-6258 HCl is a potent, orally efficacious pan-Pim kinase inhibitor with IC50 of 5 nM, 25 nM and 16 nM for Pim1, Pim2, and Pim3, respectively.