欢迎来到CSNpharm！产品仅用于科研！

400-920-2911 sales@csnpharm.cn

NEW 新产品
0

PPAR

PPAR

货号 产品名 CAS号 信息
CSN12217 2-((4-Chloro-6-((2,3-dimethylphenyl)amino)pyrimidin-2-yl)thio)acetic acid 50892-23-4 Wy-14643 is an agonist of PPARα with EC50 of 0.63 μM that can decrease the inflammatory response. It has other functions including lipid metabolism, cell proliferation, differentiation, adipogenesis etc..
CSN12155 Troglitazone 97322-87-7 Troglitazone is a PPARγ agonist with EC50 of 780 nM in murine and 555 nM in human. It has no activity at PPARα or PPARδ and can act as an anti-diabetic agent.
CSN12570 Rosiglitazone maleate   155141-29-0 Rosiglitazone maleate is the maleate form of rosiglitazone which is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-γ (PPARγ) with Kd of 40 nM and it also acts as a modulator of TRP channels.
CSN12512 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione   122320-73-4 Rosiglitazone is a selective agonist of PPARγ with EC50 of 60 nM, and has no effect on PPARα and PPARβ. It is an insulin sensitizing and potent antihyperglycemic agent.
CSN10123 Rosiglitazone HCl 302543-62-0 Rosiglitazone HCl is a blood glucose-lowering drug, stimulating insulin secretion by binding to the PPAR receptors in fat cells.
CSN10029 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione 111025-46-8 Pioglitazone is an agonist of peroxisome proliferator-activated receptor gamma (PPARγ, EC50 = 500-600 nM) over PPAR⍺. It also a thiazolidinedione (TZD) anti-diabetic.
CSN12489 Pioglitazone HCl   112529-15-4 Pioglitazone HCl is a selective agonist of PPARγ with EC50 of 0.93 μM which is used to treat diabetes.
CSN11647 Palmitoylethanolamide 544-31-0 Palmitoylethanolamide, endogenous fatty acid amide, is an agonist of PPAR-α in vitro with an EC50 value of 3.1 ± 0.4 μM. It can be used for preventing the infection of virus.
CSN11258 L-165041 79558-09-1 L-165041 is a cell permeable PPARδ agonist which induces adipocyte differentiation in NIH-PPARδ cells.
CSN18128 Inolitazone 223132-37-4 Inolitazone is a high-affinity PPARγ agonist, which activates PPARγ with an EC50 about 1/50 that of rosiglitazone and has no effect on RIE cells that do not express PPARγ.
CSN18129 Inolitazone 2HCl 223132-38-5 Inolitazone 2HCl is a high-affinity PPARγ agonist, which activates PPARγ with an EC50 about 1/50 that of rosiglitazone and has no effect on RIE cells that do not express PPARγ.
CSN11131 GW9662   22978-25-2 GW9662 selectively antagonizes PPARγ with IC50 of 3.3 nM. It can inhibit the growth of mammary cancer cells.
CSN11130 GW1929 196808-24-9 GW1929 is a synthetic peroxisome proliferator-activated receptor-γ (PPARγ) agonist with IC50 of 6.2 nM and 13 nM for human and mouse PPARγ, respectively.
CSN13142 GW0742 317318-84-6 GW0742 is an agonist of PPARδ with EC50 of 1.1 nM. It can protect right heart from hypertrophy and enhance lipid metabolism in heart. It also works as an antagonist of vitamin D receptor.
CSN15822 GSK3787 188591-46-0 GSK3787 selectively and irreversibly antagonizes PPARδ with pIC50 of 6.6 with no significant effect on hPPARα or hPPARγ.
CSN15777 GSK0660 1014691-61-2 GSK0660 is a selective antagonist of PPARβ/δ and exhibits inverse agonist effects when used alone.
CSN16260 Gemfibrozil 25812-30-0 Gemfibrozil is an agonist of PPARα. It can act as a hyperlipidemic agent that elevates plasma HDL and lowers triglycerides.
CSN12680 Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate 49562-28-9 Fenofibrate is an agonist of PPARα (EC50 = 30 μM) and an inhibitor of CYP2C19 (IC50 = 0.2 μM) and CYP2B6 (IC50 = 0.7 μM). Fenofibrate is a fibric acid derivative and used to treat hypercholesterolemia and hypertriglyceridemia.
CSN13948 Eupatilin 22368-21-4 Eupatilin is an activiator of PPARα. It is a lipohilic flavonoid extracted from artemisia species with antioxidant, anti-tumor, and anti-inflammatory activities.
CSN16153 (E)-2-(2,6-Dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxoprop-1-en-1-yl)phenoxy)-2-methylpropanoic acid 923978-27-2 Elafibranor is an agonist of PPARα and PPARδ with EC50 values of 45 nM and 175 nM, respectively. Elafibranor also attenuates nonalcoholic steatohepatitis without fibrosis worsening.
CSN13070 Clofibric acid 882-09-7 Clofibric acid is an agonist of PPARα and can act as a hypolipidemic agent.
CSN11481 Clofibrate 637-07-0 Clofibrate, a fibric acid derivative, is a selective agonist of peroxisome proliferator-activated receptor α (PPARα) with EC50 of 50 µM. Clofibrate has been used to treat hyperlipoproteinemia type III and severe hypertriglyceridemia.
CSN10653 Ciprofibrate 52214-84-3 Ciprofibrate is an agonist of peroxisome proliferator-activated receptor PPAR⍺. It is used in dyslipidaemia.
CSN10445 Bezafibrate 41859-67-0 Bezafibrate is the agonist of PPAR and the EC50 for PPAR⍺, PPARβ, PPARẟ is 50 , 20, and 60 nM respectively. It has hypolipidemic effect.
CSN14141 Arjunolic acid 465-00-9 Arjunolic acid, a natural peroxisome proliferator-activated receptor alpha agonist isolated and purified from the fruits of Terminalia chebula Retz., can protect against cisplatin-induced testicular injury by attenuating oxidative stress parameters along with downregulation of iNOS, TNF-α, and p38-MAPK testicular expressions.
CSN10234 Aleglitazar 475479-34-6 Aleglitazar is a dual PPAR-α/γ agonist with IC50 of 2.8 nM/4.6 nM.
CSN12767 4-(4-Hydroxyphenyl)-2-Butanone 5471-51-2 4-(4-Hydroxyphenyl)-2-butanone is the primary aroma compound of red raspberries and shows PPAR-α agonistic activity.
<< PREV 1 2 3 NEXT >>
dandb BBB norton fedex dhl ups 顺丰

csnpharm版权所有2023，产品仅用于科研！

联系
我们