CAS No.: 537705-08-1
(E/Z)-CP-724714 Catalog No. CSN12702
CP-724714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM, > 640-fold selectivity against EGFR, InsR, IRG-1R, PDGFR, VEGFR2, Abl, Src, c-Met etc in cell-free assays.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Feng B, Xu JJ, et al. Role of hepatic transporters in the disposition and hepatotoxicity of a HER2 tyrosine kinase inhibitor CP-724,714. Toxicol Sci. 2009 Apr;108(2):492-500.
- [2] Jani JP, Finn RS, et al. Discovery and pharmacologic characterization of CP-724,714, a selective ErbB2 tyrosine kinase inhibitor. Cancer Res. 2007 Oct 15;67(20):9887-93.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 537705-08-1 | 储存条件 |
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| 分子式 | C27H27N5O3 | 运输 | 蓝冰 | |
| 分子量 | 469.54 | 别名 |
