CAS No.: 142340-99-6
Adefovir Dipivoxil/阿德福韦酯 Catalog No. CSN16712
Synonyms: GS 0840;9-(2-((-bis((pivaloyloxy)methoxy)phosphinyl)methoxy)ethyl)adenine;GS 840
Adefovir dipivoxil can block reverse transcriptase which is crucial for the hepatitis B virus (HBV) to reproduce.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00230503 Hepatitis B, Chronic Phase 2 Completed - - NCT00230490 Hepatitis B, Chronic Phase 2 Terminated(Adverse findings fr... more >>om nonclinical carcinogenicity studies.) Collapse << - - NCT00002115 HIV Infections Phase 1 Completed - United States, Washington ... more >> Univ of Washington Seattle, Washington, United States, 98122 Collapse << - 更多
- 参考文献
- [1] Julander JG, Sidwell RW, Morrey JD. Characterizing antiviral activity of adefovir dipivoxil in transgenic mice expressing hepatitis B virus. Antiviral Res. 2002 Jul;55(1):27-40.
- [2] Delmas J, Schorr O, et al. Inhibitory effect of adefovir on viral DNA synthesis and covalently closed circular DNA formation in duck hepatitis B virus-infected hepatocytes in vivo and in vitro. Antimicrob Agents Chemother. 2002 Feb;46(2):425-33.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 142340-99-6 | 储存条件 |
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| 分子式 | C20H32N5O8P | 运输 | 蓝冰 | |||||||
| 分子量 | 501.47 | 别名 | GS 0840;9-(2-((-bis((pivaloyloxy)methoxy)phosphinyl)methoxy)ethyl)adenine;GS 840;Hepsera;Preveon;阿德福韦酯 | |||||||
| 溶解度 |
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动物实验配方 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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| NCT00230503 | Hepatitis B, Chronic | Phase 2 | Completed | - | - |
| NCT00230490 | Hepatitis B, Chronic | Phase 2 | Terminated(Adverse findings fr... more >>om nonclinical carcinogenicity studies.) Collapse << | - | - |
| NCT00002115 | HIV Infections | Phase 1 | Completed | - | United States, Washington ... more >> Univ of Washington Seattle, Washington, United States, 98122 Collapse << |
| NCT01373684 | Chronic Hepatitis B | Phase 4 | Recruiting | October 2019 | Canada ... more >> Western Hospital Recruiting Toronto, Canada Netherlands Erasmus Medical Center Recruiting Rotterdam, Zuid Holland, Netherlands, 3015 CE Contact: M.J.H. van Campenhout, MD +31107034513 m.vancampenhout@erasmusmc.nl Principal Investigator: H.L.A. Janssen, MD PhD Sub-Investigator: M.J.H. van Campenhout, MD Sub-Investigator: K.S. Liem, MD Medisch Centrum Alkmaar Recruiting Alkmaar, Netherlands Onze Lieve Vrouwen Gasthuis Recruiting Amsterdam, Netherlands VU university medical center Recruiting Amsterdam, Netherlands Rijnstate Hospital Recruiting Arnhem, Netherlands Reinier de Graaf Gasthuis Recruiting Delft, Netherlands MC Haaglanden Recruiting Den Haag, Netherlands Catharina ziekenhuis Recruiting Eindhoven, Netherlands Spaarne Gasthuis Recruiting Haarlem, Netherlands Atrium Medical Center Recruiting Heerlen, Netherlands LUMC Recruiting Leiden, Netherlands Radboud University Medical Center Recruiting Nijmegen, Netherlands University Medical Center Utrecht Recruiting Utrecht, Netherlands Collapse << |
| NCT03736265 | Cirrhosis, Liver ... more >> Portal Hypertension Collapse << | Not Applicable | Recruiting | December 2021 | China, Beijing ... more >> Beijing Ditan Hospital Capital Medical University Recruiting Beijing, Beijing, China, 100015 Contact: Wen Xie Xiewen6218@163.com Peking University First Hospital Recruiting Beijing, Beijing, China, 100034 Contact: Xiaoyuan Xu yangpin@public3.bta.net.com Peking University People's Hospital Recruiting Beijing, Beijing, China, 100044 Contact: Bo Feng xyfyfb_1@sina.com Beijing Friendship Hospital Recruiting Beijing, Beijing, China, 100050 Contact: Xiaoning Wu China, Shanghai Zhongshan Hospital Fudan University Recruiting Shanghai, Shanghai, China, 200032 Contact: Wei Jiang jiang.wei@zs-hospital.sh.cn The First Affiliated Hospital of Shanghai Jiao Tong University Recruiting Shanghai, Shanghai, China, 201620 Contact: Mingyi Xu xumingyi@hotmail.com Collapse << |
| NCT00410202 | Hepatitis B, Chronic | Phase 3 | Completed | - | - |
| NCT00734162 | Hepatitis B Virus (HBV) | Phase 3 | Completed | - | United States, California ... more >> Children's Hospital & Research Center at Oakland Oakland, California, United States, 94609 United States, Indiana Riley Hospital for Children Indianapolis, Indiana, United States, 46202 United States, Washington Children's Hospital & Regional Medical Center, d/b/a Seattle Children's Research Institute Seattle, Washington, United States, 98105 Bulgaria Multiprofile Hospital for Active Treatment Sveti Georgi Plovdiv, Bulgaria, 4002 Clinic of Gastroenterology, Specialized Hospital for Active Treatment of Pediatric Diseases, Sofia Sofia, Bulgaria, 1606 France Hopital Femmes Meres Enfants Bron Cedex, France, 69677 Hôpital Claude Huriez Lille Cedex, France, 59037 Poland Samodzielny Publiczny Dzieciecy Szpital Kliniczny Akademii Medycznej w Bialymstoku Białystok, Poland, 15-274 Wojewodzki Specjalistyczny Szpital im Bieganskiego Bydgoszcz, Poland, 85-030 Wojewodzki Szpital Obserwacyjno-Zakazny im. T. Browicza Bydgoszcz, Poland, 85-030 Krakowski Szpital Specjalistyczny im. Jana Pawla II Kraków, Poland, 31-202 Samodzielny Publiczny Szpital Kliniczny im. Karola Johschera Poznan, Poland, 60-572 Specjalistyczny Zespol Opieki Zdrowotnej nad Matka i Dzieckiem Poznań, Poland, 61-734 Wojewodzki Szpital Zakazny Warszawa, Poland, 01-201 Samodzielny Publiczny Szpital Kliniczny Nr 1 Wrocław, Poland, 50-368 Romania Fundeni Clinical Institute Bucharest, Romania, 022328 Institute for Infectious Diseases Bucharest, Romania, 21105 Cluj Childrens Emergency Hospital Napaco, Romania, 400217 Spain Hosp Univ y Politecnico La Fe de Valencia Madrid, Spain, 28046 Hospital Universitario De Getafe Madrid, Spain, 46009 Turkey Ege Universitesi Tip Fakultesi Hastanesi Izmir, Turkey, 35100 Collapse << |
| NCT03366571 | - | - | Recruiting | December 2019 | China, Beijing ... more >> China-Japan Friendship Hospital Recruiting Beijing, Beijing, China, 100029 Contact: Anlin Ma, Doctor 13910253710 maanlinjc@163.com Principal Investigator: Anlin Ma, Doctor Peking University First Hospital Recruiting Beijing, Beijing, China, 100034 Contact: Xiaoyuan Xu, Doctor 13001185762 xiaoyuanxu6@163.com Principal Investigator: Xiaoyuan Xu, Doctor Beijing 302 Hospital Recruiting Beijing, Beijing, China Contact: Feng G Chen bjchen302@aliyun.com Principal Investigator: Feng G Chen Beijing Ditan Hospital Recruiting Beijing, Beijing, China Contact: Wen Xie Beijing Tiantan Hospital Recruiting Beijing, Beijing, China Contact: Qing Y Xu Beijing YouAn Hospital Recruiting Beijing, Beijing, China Contact: Guo H Ding, Doctor 8613699119545 lilei_1978@aliyun.com Peking Union Medical College Hospital Recruiting Beijing, Beijing, China Contact: Qing X Liu PeKing University People's Hopital Recruiting Beijing, Beijing, China Contact: Hui Ma, Doctor 8613671090481 mahui_wj@163.com Collapse << |
| NCT00810524 | Hepatitis B, Chronic | Phase 4 | Unknown | January 2017 | China, Guangdong ... more >> The Third Affiliated Hospital Of Sun Yat-sen University Recruiting Guangzhou, Guangdong, China Contact: Gao zhiliang, M. D. +862085252037 zhanlianh@21cm.com Recruiting Guangzhou, Guangdong, China Contact: Gao zhiliang, M. D. +8685252037 Principal Investigator: gao zhiliang, doctor Collapse << |
| NCT00895596 | Chronic Hepatitis B | Phase 1 Phase 2 | Completed | - | China ... more >> Queen Mary Hospital Hong Kong, China Korea, Republic of Korea University Medical Center Seoul, Korea, Republic of Severance Hospital of Yonsei University Seoul, Korea, Republic of The Catholic University of Korea, Kangnam St. Mary's Hospital Seoul, Korea, Republic of Collapse << |
| NCT02743260 | Healthy | Phase 4 | Unknown | December 2017 | Germany ... more >> Department of Pharmacology I, University Hospital Cologne Cologne, NRW, Germany, 50931 Collapse << |
| NCT01925820 | Chronic Hepatitis B | Phase 4 | Unknown | - | Taiwan ... more >> National Taiwan University Hospital Department of Internal Medicine Recruiting Taipei, Taiwan Contact: Pei-Jer Chen 886-2-23123456 ext 67072 peijerchen@ntu.edu.tw Principal Investigator: Pei-Jer Chen Collapse << |
| NCT00275938 | Chronic Hepatitis B | Phase 2 Phase 3 | Completed | - | - |
| NCT00640588 | Hepatitis B, Chronic | Phase 3 | Completed | - | Spain ... more >> Novartis Investigative Site Barcelona, Spain Collapse << |
| NCT00410202 | - | - | Completed | - | - |
| NCT01918631 | Chronic Heptitis B | Not Applicable | Completed | - | Hong Kong ... more >> Prince of Wales Hospital Hong Kong, Hong Kong Collapse << |
| NCT01623778 | - | - | Completed | - | China, Shanghai ... more >> Changhai hospital Shanghai, Shanghai, China, 200433 Collapse << |
| NCT00986778 | Hepatitis B, Chronic | Phase 4 | Withdrawn(Business Objectives ... more >>Changed) Collapse << | June 2014 | - |
| NCT00798460 | Chronic Hepatitis B | Phase 4 | Terminated(could not enroll pa... more >>tients) Collapse << | - | Korea, Republic of ... more >> Ilsanpaik hospital Goyang, Gyunggi, Korea, Republic of, 411-706 Collapse << |
| NCT00734162 | - | - | Completed | - | - |
| NCT01732367 | Chronic Hepatitis B | Phase 4 | Completed | - | Korea, Republic of ... more >> Department of Internal Medicine, Keimyung University Dongsan Medical Center Daegu, Korea, Republic of, ASI|KR|KS002|TAEGU Collapse << |
| NCT01491295 | Chronic Hepatitis B | Phase 4 | Recruiting | December 2019 | Taiwan ... more >> Taipei Veterans General Hospital-Division of Gastroenterology Recruiting Taipei, Taiwan, 11217 Contact: Yi-Hsiang Huang 886-28712121 ext 3055 yhhuang@vghtpe.gov.tw Principal Investigator: Yi-Hsiang Huang Collapse << |
| NCT02327663 | Hepatitis B, Chronic | Phase 4 | Unknown | December 2017 | - |
| NCT00059267 | - | - | Completed | - | United States, Michigan ... more >> University of Michigan Ann Arbor, Michigan, United States, 48109 Collapse << |
| NCT00513968 | Chronic Hepatitis B | Phase 1 | Completed | - | Korea, Republic of ... more >> Kangnam St. Mary's Hospital Seoul, Korea, Republic of, 137-701 Collapse << |
| NCT01804387 | Chronic Hepatitis B | Phase 4 | Unknown | May 2014 | Korea, Republic of ... more >> Korea University Ansan Hospital Recruiting Ansan, Gyeonggi-do, Korea, Republic of, 425-707 Contact: Hyung Joon Yim, M.D 82-31-412-5583 gudwns21@medimail.co.kr Collapse << |
| NCT01597934 | Chronic Hepatitis B | Phase 4 | Unknown | May 2014 | - |
| NCT00001087 | HIV Infections | Phase 2 | Completed | - | United States, Illinois ... more >> Northwestern University CRS Chicago, Illinois, United States, 60611 Cook County Hosp. CORE Ctr. Chicago, Illinois, United States, 60612 Rush Univ. Med. Ctr. ACTG CRS Chicago, Illinois, United States, 60612 United States, Maryland Johns Hopkins Adult AIDS CRS Baltimore, Maryland, United States, 21287 United States, New York NY Univ. HIV/AIDS CRS New York, New York, United States Puerto Rico Puerto Rico-AIDS CRS San Juan, Puerto Rico, 009365067 Collapse << |
| NCT02965859 | Chronic Hepatitis B | Phase 2 | Unknown | - | China, Jiangsu ... more >> 81 Military Hospital of China Recruiting Nanjing, Jiangsu, China Contact: Maorong Wang 025-80864021 Principal Investigator: Maorong Wang Collapse << |
| NCT01023217 | Hepatitis B, Chronic | Phase 4 | Completed | - | Korea, Republic of ... more >> Asan Medical Center Seoul, the Meteropolis of Seoul, Korea, Republic of, 138-736 Collapse << |
| NCT00000885 | HIV Infections | Phase 2 | Completed | - | - |
| NCT01264354 | Chronic Hepatitis B | Phase 4 | Completed | - | Korea, Republic of ... more >> Samsung Medical Center Seoul, Korea, Republic of Collapse << |
| NCT00000912 | HIV Infections | Phase 2 | Completed | - | - |
| NCT02826070 | Hepatitis B, Chronic | Phase 4 | Unknown | October 2017 | China, Beijing ... more >> 302 Military Hospital Of China Beijing, Beijing, China Beijing Ditan Hospital Beijing, Beijing, China BeiJing YouAn Hospital ,Capital Medical University Beijing, Beijing, China Department of infectious disease, First Hospital of Peking University Beijing, Beijing, China People's Hospital of Beijing University Beijing, Beijing, China China, Chongqing The Second Affiliated of ChongQing University of Medical Science Chongqing, Chongqing, China China, Guangdong Department of Infectious Disease, Nanfang Hospital Guangzhou, Guangdong, China No. 8 People's Hospital In GuangZhou Guangzhou, Guangdong, China The Third Hospital of Sun Yat-Sen University Guangzhou, Guangdong, China China, Hubei Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology Wuhan, Hubei, China China, Hunan Xiangya Hospital Central-South Univrsity Changsha, Hunan, China China, Jiangsu No.81 Hospital of PLA Nanjing, Jiangsu, China China, Jilin First Hospital .Jilin Unniversity Changchun, Jilin, China China, Liaoning ShengJing Hospital of China Medical University Shengyang, Liaoning, China China, Shandong JiNan Infectious Diseases Hospital Jinan, Shandong, China China, Shanghai Changhai Hospital affiliated to Second Military Medical University Shanghai, Shanghai, China Huashan Hospital，Fudan University Shanghai, Shanghai, China Shanghai Ruijin Hospital Shanghai, Shanghai, China China, Shanxi Tangdu Hospital XiAn, Shanxi, China China, Zhejiang The First Affiliated Hospital of College of Medicine, Zhejiang University Hangzhou, Zhejiang, China Collapse << |
| NCT00000892 | HIV Infections | Not Applicable | Completed | - | - |
| NCT01023217 | - | - | Completed | - | - |
| NCT00023309 | - | - | Completed | - | - |
| NCT01720238 | - | - | Unknown | December 2018 | China, Beijing ... more >> Beijing Friendship Hospital Beijing, Beijing, China, 100050 Beijing 302 Hospital Beijing, Beijing, China Beijing Ditan Hospital Beijing, Beijing, China Beijing Tiantan Hospital Beijing, Beijing, China Beijing YouAn Hospital Beijing, Beijing, China Peking Union Medical College Hospital Beijing, Beijing, China PeKing University People's Hopital Beijing, Beijing, China The First Hospital of Peking University Beijing, Beijing, China Collapse << |
| NCT00023309 | HBV (Hepatitis B Virus) ... more >> Hepatitis B Hepatitis Collapse << | Phase 2 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
| NCT02327416 | Hepatitis B, Chronic | Phase 3 | Recruiting | June 2019 | China, Beijing ... more >> Beijing Youan Hospital Recruiting Beijing, Beijing, China, 100069 Contact: Xinyue Chen, Doctor 86 13911212398 chenxydoc@163.com Contact: Yali Liu, Doctor 86 13260255331 xxbi@163.com Principal Investigator: Xinyue Chen, Doctor China, Hubei Tongji Hospital Recruiting Wuhan, Hubei, China, 430030 Contact: Qin Ning, Doctor 86 27 83662391 qning@vip.sina.com Contact: Meifang Han, Doctor 86 27 83662391 hanmeifang@hotmail.com Principal Investigator: Qin Ning, Doctor China, Hunan Xiangya Hospital, Central South University Recruiting Changsha, Hunan, China, 410008 Contact: Deming Tan, Doctor 86 13975886582 dmt3008@163.com Contact: Lei Fu, Doctor 86 15084739488 936512615@qq.com Principal Investigator: Deming Tan, Doctor China, Zhejiang The First Affiliated Hospital of Wenzhou Medical University Recruiting Wenzhou, Zhejiang, China, 325000 Contact: Yongping Chen, Doctor 86 13505777281 13505777281@163.com Contact: Lanman Xu, Doctor 86 13587646315 13587646315@163.com Principal Investigator: Yongping Chen, Doctor Collapse << |
| NCT01521975 | Hepatitis B, Chronic | Phase 4 | Completed | - | China, Guangdong ... more >> The Third Affiliated Hospital of Sun Yat-sen University Guangzhou, Guangdong, China, 510630 Collapse << |
| NCT02598063 | Hepatitis B, Chronic | Phase 4 | Completed | - | China ... more >> Beijing, China, 100044 Beijing, China, 100050 Beijing, China, 100054 Chongqing, China, 400038 Guangzhou, China, 510515 Hangzhou, China, 310003 Jinan, China, 250021 Shanghai, China, 200025 Shanghai, China, 200040 Shanghai, China, 201508 Hong Kong Hong Kong, Hong Kong, 852 Hong Kong, Hong Kong Collapse << |
| NCT01863589 | - | - | Completed | - | - |
| NCT01718587 | Liver Cirrhosis | Phase 1 Phase 2 | Unknown | July 2014 | China ... more >> Yihua An Beijing, China Collapse << |
| NCT00002346 | HIV Infections | Phase 1 | Completed | - | United States, Maryland ... more >> Johns Hopkins Univ Baltimore, Maryland, United States, 21205 Collapse << |
| NCT00715715 | Chronic Hepatitis B | Not Applicable | Withdrawn(Withdrawn studies.) | - | United States, New York ... more >> Maimonides Medical Center Brooklyn, New York, United States, 11219 Collapse << |
| NCT00199732 | - | - | Completed | - | France ... more >> Service d'Hépato-gastroentérologie Limoges, France Service de Médecine Interne Limoges, France Service de Virologie Limoges, France Service des Maladies Infectieuses et Tropicales Limoges, France Collapse << |
| NCT02075294 | - | - | Completed | - | China, Beijing ... more >> 302 military hospital of China Beijing, Beijing, China, 100039 Collapse << |
| NCT00051077 | HIV Infections ... more >> Hepatitis B Hepatitis C Collapse << | Phase 2 | Withdrawn | - | - |
| NCT00023153 | HIV Infections ... more >> Chronic Hepatitis B Collapse << | Phase 3 | Completed | - | United States, Maryland ... more >> National Institute of Allergy and Infectious Diseases (NIAID) Bethesda, Maryland, United States, 20892 Collapse << |
| NCT00672867 | Patients With LC-B | Phase 3 | Completed | - | Korea, Republic of ... more >> Samsung Medical Center Seoul, Korea, Republic of Collapse << |
| NCT00371761 | Hepatitis B, Chronic (CHB) | Phase 3 | Completed | - | - |
| NCT00033163 | HIV Infections ... more >> Hepatitis B Collapse << | Phase 2 | Completed | - | United States, California ... more >> UC Davis Medical Center Sacramento, California, United States, 95814 Univ. of California Davis Med. Ctr., ACTU Sacramento, California, United States Ucsf Aids Crs San Francisco, California, United States, 94110 United States, Colorado University of Colorado Hospital CRS Aurora, Colorado, United States, 80262 United States, Illinois Northwestern University CRS Chicago, Illinois, United States, 60611 Cook County Hosp. CORE Ctr. Chicago, Illinois, United States, 60612 United States, Maryland Johns Hopkins Adult AIDS CRS Baltimore, Maryland, United States, 21287 United States, New York Beth Israel Med. Ctr., ACTU New York, New York, United States, 10003 NY Univ. HIV/AIDS CRS New York, New York, United States, 10016 Cornell CRS New York, New York, United States, 10021 Weill Med. College of Cornell Univ., The Cornell CTU New York, New York, United States United States, Ohio Univ. of Cincinnati CRS Cincinnati, Ohio, United States, 452670405 MetroHealth CRS Cleveland, Ohio, United States, 441091998 United States, Tennessee Vanderbilt Therapeutics CRS Nashville, Tennessee, United States, 37203 United States, Washington University of Washington AIDS CRS Seattle, Washington, United States, 98104 Collapse << |
| NCT00376259 | Hepatitis B | Phase 3 | Terminated(The study was not c... more >>ompleted as planned and was terminated early with agreement from the European Medicines Agency (EMEA)) Collapse << | - | United States, California ... more >> Novartis San Diego, California, United States San Mateo, California, United States Hong Kong Pok Fu Lam, Hong Kong Korea, Republic of Seoul, Korea, Republic of Taiwan Novarits Kaohsuing, Taiwan Thailand Bangkok, Thailand Collapse << |
| NCT00371761 | - | - | Completed | - | - |
| NCT00376259 | - | - | Terminated(The study was not c... more >>ompleted as planned and was terminated early with agreement from the European Medicines Agency (EMEA)) Collapse << | - | - |
| NCT00307489 | Chronic Hepatitis B | Phase 2 | Completed | - | United States, California ... more >> San Francisco, California, United States, 94115 San Jose, California, United States, 95128 United States, New York Flushing, New York, United States, 11355 New York, New York, United States, 10013 New York, New York, United States, 10016 New York, New York, United States, 10021 United States, Pennsylvania Philadelphia, Pennsylvania, United States, 19107 United States, Virginia Fairfax, Virginia, United States, 22031 Norfolk, Virginia, United States, 23502 Richmond, Virginia, United States, 23249 France Angers, France, 49933 Clichy, France, 92110 Lille, France, 59037 Lyon, France, 69288 Marseille, France, 13285 Rouen, France, 76031 Strasbourg, France, 67091 Germany Berlin, Germany, 10969 Berlin, Germany, 13353 Bonn, Germany, 53105 Erlangen, Germany, 91054 Essen, Germany, 45122 Frankfurt, Germany, 60590 Hamburg, Germany, 20999 Hannover, Germany, 30623 Herne, Germany, 44623 Munchen, Germany, 81377 Spain Sevilla, Spain, 41014 Collapse << |
| NCT00002184 | HIV Infections | Phase 2 | Completed | - | United States, Arizona ... more >> Phoenix Body Positive Phoenix, Arizona, United States, 85016 United States, California Krauss Med Partners / Dept of Research and Development Los Angeles, California, United States, 90036 UCLA Care Ctr Los Angeles, California, United States, 900951793 Davies Med Ctr San Francisco, California, United States, 94114 United States, Connecticut Blick Med Associates Greenwich, Connecticut, United States, 06830 United States, District of Columbia George Washington Med Ctr Washington, District of Columbia, United States, 20037 United States, Maryland Johns Hopkins Univ School of Medicine Baltimore, Maryland, United States, 21287 United States, Massachusetts Univ of Massachusetts Med Ctr Worcester, Massachusetts, United States, 01655 United States, New York North Shore Community Hosp Manhassett, New York, United States, 11030 United States, Oklahoma Associates of Med and Mental Health Tulsa, Oklahoma, United States, 74114 United States, Pennsylvania Univ of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 United States, Rhode Island Mem Hosp of Rhode Island Pawtucket, Rhode Island, United States, 02860 United States, Texas Univ of Texas Southwestern Med Ctr of Dallas Dallas, Texas, United States, 75235 Puerto Rico Hosp Regional de Ponce - Area Vieja Ponce, Puerto Rico, 00731 San Juan AIDS Program Santruce, Puerto Rico, 00908 Collapse << |
| NCT00002398 | HIV Infections | Not Applicable | Completed | - | United States, California ... more >> Gilead Sciences Inc Foster City, California, United States, 94404 Collapse << |
| NCT00002379 | HIV Infections | Phase 2 | Completed | - | United States, Arizona ... more >> Phoenix Body Positive Phoenix, Arizona, United States, 85016 United States, California AIDS Healthcare Foundation Labs Los Angeles, California, United States, 90027 Davies Med Ctr San Francisco, California, United States, 94114 United States, Connecticut Blick Med Associates Greenwich, Connecticut, United States, 06830 United States, District of Columbia George Washington Med Ctr Washington, District of Columbia, United States, 20037 United States, Illinois Cook County Gen Hosp / Division of Infect Diseases Chicago, Illinois, United States, 60612 United States, Maryland Johns Hopkins Univ School of Medicine Baltimore, Maryland, United States, 21287 United States, Massachusetts Community Research Initiative Brookline, Massachusetts, United States, 02445 United States, New York Community Research Initiative on AIDS New York, New York, United States, 10001 Saint Vincent's AIDS Ctr New York, New York, United States, 10011 United States, Pennsylvania Hershey Med Ctr / Dept of Hematology Hershey, Pennsylvania, United States, 17033 United States, Rhode Island Mem Hosp of Rhode Island Pawtucket, Rhode Island, United States, 02860 United States, Texas Univ of Texas Southwestern Med Ctr of Dallas Dallas, Texas, United States, 75235 United States, Washington Swedish Med Ctr Seattle, Washington, United States, 98122 Puerto Rico Hosp Regional de Ponce - Area Vieja Ponce, Puerto Rico, 00731 Collapse << |
| NCT00013702 | Hepatitis B H... more >>IV Infection Collapse << | Phase 2 | Completed | - | United States, Maryland ... more >> National Institute of Allergy and Infectious Diseases (NIAID) Bethesda, Maryland, United States, 20892 Collapse << |
| NCT00002234 | HIV Infections | Phase 2 | Completed | - | United States, California ... more >> Pacific Oaks Med Group Beverly Hills, California, United States, 90211 United States, Colorado Univ of Colorado / Health Science Ctr Denver, Colorado, United States, 80262 United States, Georgia AIDS Research Consortium of Atlanta Atlanta, Georgia, United States, 30308 United States, Rhode Island Brown Univ School of Medicine Providence, Rhode Island, United States, 02908 United States, Virginia Hampton Roads Med Specialists Hampton, Virginia, United States, 23666 Collapse << |
| NCT00002219 | HIV Infections | Phase 2 | Unknown | - | United States, Florida ... more >> All Children's Hosp St. Petersburg, Florida, United States, 33731 United States, Louisiana Tulane Univ Med Ctr / Dept of Pediatrics New Orleans, Louisiana, United States, 70112 United States, New York Bronx Lebanon Hosp Ctr / Dept of Pediatrics Bronx, New York, United States, 10457 North Shore Univ Hosp / Division of Immunology Great Neck, New York, United States, 11021 St Lukes Roosevelt Hosp Ctr New York, New York, United States, 10025 United States, North Carolina Duke Univ Med Ctr / Duke South Hosp Durham, North Carolina, United States, 27710 United States, South Carolina Med Univ of South Carolina Charleston, South Carolina, United States, 29425 Collapse << |
| NCT00973219 | Chronic Hepatitis B | Not Applicable | Unknown | November 2018 | Netherlands ... more >> Academic Medical Center Amsterdam, Noord-Holland, Netherlands, 1100 AZ Collapse << |
| NCT00531167 | Chronic Hepatitis B | Phase 4 | Completed | - | Korea, Republic of ... more >> Korea University Ansan Hospital Ansan, Gyeonggi-do, Korea, Republic of Korea University Anam Hospital Seoul, Korea, Republic of Collapse << |
| NCT01300234 | - | - | Completed | - | - |
| NCT00002419 | HIV Infections | Phase 2 | Completed | - | United States, California ... more >> Pacific Oaks Med Group Beverly Hills, California, United States, 90211 United States, Colorado Univ of Colorado / Health Science Ctr Denver, Colorado, United States, 80262 United States, Georgia AIDS Research Consortium of Atlanta Atlanta, Georgia, United States, 30308 United States, Rhode Island Brown Univ School of Medicine Providence, Rhode Island, United States, 02908 United States, Virginia Hampton Roads Med Specialists Hampton, Virginia, United States, 23666 Collapse << |
| NCT00002220 | HIV Infections | Phase 3 | Completed | - | United States, California ... more >> LAC / USC Med Ctr / Infectious Diseases Los Angeles, California, United States, 90033 United States, Connecticut Yale Univ / AIDS Clinical Trials Unit New Haven, Connecticut, United States, 06510 United States, Delaware Med Ctr of Delaware Wilmington, Delaware, United States, 19899 United States, Hawaii Hawaii AIDS Clinical Trial Unit Honolulu, Hawaii, United States, 96816 United States, Illinois Rush Presbyterian Saint Lukes Med Ctr Chicago, Illinois, United States, 606123832 United States, Maryland Johns Hopkins Hosp Baltimore, Maryland, United States, 212876220 United States, Massachusetts Massachusetts Gen Hosp Boston, Massachusetts, United States, 02114 United States, New York Columbia Presbyterian Hosp New York, New York, United States, 10032 AIDS TMT Unit / Univ Hosp Stonybrook, New York, United States, 117948153 United States, Tennessee Vanderbilt Clinic Nashville, Tennessee, United States, 37212 United States, Texas Oaklawn Physicians Group Dallas, Texas, United States, 75219 Collapse << |
| NCT00117676 | Chronic Hepatitis B | Phase 3 | Completed | - | - |
| NCT00117676 | - | - | Completed | - | - |
| NCT00158717 | - | - | Completed | - | - |
| NCT00307489 | - | - | Completed | - | - |
| NCT01146808 | Hepatitis B L... more >>iver Transplantation Collapse << | Phase 1 Phase 2 | Completed | - | United States, New York ... more >> Center for Liver Disease and Transplantation at Columbia University Medical Center New York, New York, United States, 10032 Collapse << |
| NCT00606099 | Chronic Hepatitis B | Phase 4 | Withdrawn(study was cancelled) | - | United States, Georgia ... more >> Novartis Atlanta, Georgia, United States, 30308 United States, New York Novartis Flushing, New York, United States, 11355 United States, Virginia Novartis Sterling, Virginia, United States, 20166 Collapse << |
| NCT01300234 | Hepatitis B | Phase 3 | Completed | - | China, Guangdong ... more >> GSK Investigational Site Guangzhou, Guangdong, China, 510060 GSK Investigational Site Guangzhou, Guangdong, China, 510515 GSK Investigational Site Guangzhou, Guangdong, China, 510630 China, Hubei GSK Investigational Site Wuhan, Hubei, China, 430030 China, Hunan GSK Investigational Site Changsha, Hunan, China, 410008 China, Jiangsu GSK Investigational Site Nanjing, Jiangsu, China, 210003 GSK Investigational Site Nanjing, Jiangsu, China, 210029 China, Jilin GSK Investigational Site Changchun, Jilin, China, 130021 China, Sichuan GSK Investigational Site Chengdu, Sichuan, China, 610041 China, Zhejiang GSK Investigational Site Hangzhou, Zhejiang, China, 310003 China GSK Investigational Site Beijing, China, 100015 GSK Investigational Site Beijing, China, 100044 GSK Investigational Site Beijing, China, 100050 GSK Investigational Site Chongqing, China, 400038 GSK Investigational Site Fuzhou, China, 350025 GSK Investigational Site Jinan, China, 250021 GSK Investigational Site Shanghai, China, 200001 GSK Investigational Site Shanghai, China, 200025 GSK Investigational Site Shanghai, China, 200040 GSK Investigational Site Shanghai, China, 201508 Collapse << |
| NCT00116805 | Chronic Hepatitis B | Phase 3 | Completed | - | - |
| NCT00116805 | - | - | Completed | - | - |
| NCT00187746 | Other Conditions That May Be A... more >> Focus of Clinical Attention Collapse << | Phase 4 | Withdrawn(Budget exceeded for ... more >>project.) Collapse << | - | United States, California ... more >> San Francisco General Hospital San Francisco, California, United States, 94143 Collapse << |
| NCT00002161 | HIV Infections | Not Applicable | Completed | - | - |
| NCT00115245 | Chronic Hepatitis B | Phase 3 | Completed | - | United States, California ... more >> Los Angeles, California, United States Pasadena, California, United States San Francisco, California, United States United States, Florida Miami, Florida, United States Australia Clayton, Australia Wooloongabba, Australia Canada Calgary, Canada Toronto, Canada Winnipeg, Canada China Hong Kong, China France Paris, France Korea, Republic of Seoul, Korea, Republic of Singapore Singapore, Singapore Taiwan Taipei, Taiwan Thailand Bangkok, Thailand Collapse << |
| NCT00000843 | HIV Infections | Phase 1 | Completed | - | United States, California ... more >> UCSF / Moffitt Hosp - Pediatric San Francisco, California, United States, 941430105 United States, Florida Univ of Florida Health Science Ctr / Pediatrics Jacksonville, Florida, United States, 32209 United States, Illinois Chicago Children's Memorial Hosp Chicago, Illinois, United States, 606143394 United States, Maryland Johns Hopkins Hosp - Pediatric Baltimore, Maryland, United States, 212874933 United States, Massachusetts Children's Hosp of Boston Boston, Massachusetts, United States, 021155724 United States, New Jersey Children's Hosp of New Jersey / UMDNJ - New Jersey Med Schl Newark, New Jersey, United States, 071072198 United States, Pennsylvania Children's Hosp of Philadelphia Philadelphia, Pennsylvania, United States, 191044318 United States, Tennessee Saint Jude Children's Research Hosp of Memphis Memphis, Tennessee, United States, 381052794 Vanderbilt Univ Med Ctr Nashville, Tennessee, United States, 372322581 Puerto Rico Univ of Puerto Rico / Univ Children's Hosp AIDS San Juan, Puerto Rico, 009365067 Collapse << |
| NCT00661076 | Hepatitis B, Chronic | Phase 3 | Completed | - | Turkey ... more >> Ankara, Turkey, 06018 Ankara, Turkey, 06100 Ankara, Turkey, 06500 Ankara, Turkey, 06800 Gaziantep, Turkey, 27310 Collapse << |
| NCT00042393 | - | - | - | - | - |
| NCT01146808 | - | - | Completed | - | - |
| NCT00071201 | Chronic Hepatitis B | Phase 3 | Completed | - | United States, California ... more >> Gilead Sciences, Inc. 333 Lakeside Drive Foster City, California, United States, 94404 Collapse << |
| NCT00002128 | HIV Infections | Phase 1 | Completed | - | United States, Maryland ... more >> Johns Hopkins Univ Baltimore, Maryland, United States, 21205 Collapse << |
| NCT00002426 | HIV Infections | Not Applicable | Completed | - | - |
| NCT00001082 | Cytomegalovirus Infections ... more >> HIV Infections Collapse << | Phase 3 | Completed | - | United States, California ... more >> Community Consortium / UCSF San Francisco, California, United States, 94110 United States, Colorado Denver CPCRA / Denver Public Hlth Denver, Colorado, United States, 80204 United States, District of Columbia Washington Reg AIDS Prog / Dept of Infect Dis Washington, District of Columbia, United States, 20422 United States, Georgia AIDS Research Consortium of Atlanta Atlanta, Georgia, United States, 30308 United States, Illinois AIDS Research Alliance - Chicago Chicago, Illinois, United States, 60657 United States, Louisiana Louisiana Comm AIDS Rsch Prog / Tulane Univ Med New Orleans, Louisiana, United States, 70112 United States, Michigan Wayne State Univ - WSU/DMC / Univ Hlth Ctr Detroit, Michigan, United States, 48201 Henry Ford Hosp Detroit, Michigan, United States, 48202 United States, New Jersey Southern New Jersey AIDS Cln Trials / Dept of Med Camden, New Jersey, United States, 08103 North Jersey Community Research Initiative Newark, New Jersey, United States, 07103 United States, New Mexico Partners in Research / New Mexico Albuquerque, New Mexico, United States, 87131 United States, New York Harlem AIDS Treatment Grp / Harlem Hosp Ctr New York, New York, United States, 10037 United States, Oregon The Research and Education Group Portland, Oregon, United States, 97210 United States, Pennsylvania Philadelphia FIGHT Philadelphia, Pennsylvania, United States, 19107 United States, Virginia Richmond AIDS Consortium / Div of Infect Diseases Richmond, Virginia, United States, 23298 Collapse << |
| NCT00002206 | HIV Infections | Phase 1 | Completed | - | United States, District of Col... more >>umbia Anderson Clinical Research Washington, District of Columbia, United States, 20037 United States, Maryland Johns Hopkins Univ Clinical Pharmacology Baltimore, Maryland, United States, 21287 United States, New York Anderson Clinical Research New York, New York, United States, 10016 United States, Pennsylvania Anderson Clinical Research Philadelphia, Pennsylvania, United States, 19107 Anderson Clinical Research / Inc Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT00753467 | Hepatitis B | Phase 2 | Unknown | August 2009 | United States, California ... more >> Huntington Medical Research Institutes Not yet recruiting Pasadena, California, United States, 91105 Contact: Lori Tong, RN 626-397-5827 ltong@hmri.org Principal Investigator: Myron J Tong, PhD, MD Collapse << |
| NCT00316719 | Chronic Hepatitis B | Phase 3 | Completed | - | - |
| NCT00316719 | - | - | Completed | - | - |
| NCT00095121 | Chronic Hepatitis B | Phase 3 | Completed | - | United States, Massachusetts ... more >> Boston, Massachusetts, United States Collapse << |
| NCT00095121 | - | - | Completed | - | - |
| NCT00455091 | - | - | Terminated(No cases enrollment... more >>) Collapse << | April 2018 | Taiwan ... more >> Chang-Gung Memorial Hospital Kaohsiung, Taiwan Kaohsiung Medical University Chung-Ho Memorial Hospital Kaohsiung, Taiwan Veterans General Hospital-Kaohsiung Kaohsiung, Taiwan Chang-Gung Memorial Hospital (Lin-Kou) Taichung, Taiwan Taichung Veterans General Hospital Taichung, Taiwan National Cheng Kung University Hospital Tainan, Taiwan National Taiwan University Hospital Taipei, Taiwan Veterans General Hospital-Taipei Taipei, Taiwan Collapse << |
| NCT00641082 | HBeAg(-) Chronic Hepatitis B W... more >>ith Compensated Liver Function Collapse << | Phase 4 | Completed | - | Korea, Republic of ... more >> Seoul National University Bundang Hospital Bundang, Korea, Republic of Seoul National University Hospital Seoul, Korea, Republic of Collapse << |
| NCT00307242 | Chronic Hepatitis B | Phase 4 | Completed | - | - |
| NCT00158704 | Hepatitis B | Not Applicable | Terminated(The study stopped d... more >>ue to marketing approval by the FDA.) Collapse << | - | - |
| NCT01581242 | Healthy | Phase 1 | Completed | - | Korea, Republic of ... more >> Clinical Trial Center, Seoul National University Hospital Seoul, Korea, Republic of Collapse << |
| NCT00857675 | Chronic Hepatitis B | Phase 3 | Completed | - | China, Guangdong ... more >> GSK Investigational Site Guangzhou, Guangdong, China, 510515 GSK Investigational Site Guangzhou, Guangdong, China, 510630 China, Jilin GSK Investigational Site Changchun, Jilin, China, 130021 China, Shandong GSK Investigational Site Jinan, Shandong, China China, Zhejiang GSK Investigational Site Hangzhou, Zhejiang, China, 310003 China GSK Investigational Site Beijing, China, 100011 GSK Investigational Site Beijing, China, 100044 GSK Investigational Site Chongqing, China, 400038 GSK Investigational Site Chongquin, China, 400038 GSK Investigational Site Shanghai, China, 200040 Collapse << |
| NCT00403585 | Hepatitis B, Chronic ... more >> Chronic Hepatitis B Collapse << | Phase 4 | Completed | - | Korea, Republic of ... more >> GSK Investigational Site Seoul, Korea, Republic of, 137-701 Collapse << |
| NCT01205165 | Hepatitis B, Chronic | Phase 4 | Completed | - | - |
| NCT00403585 | - | - | Completed | - | - |
| NCT00230477 | Hepatitis B | Phase 4 | Completed | - | United States, Washington ... more >> Harborview Medical Center Seattle, Washington, United States, 98104 Collapse << |
| NCT00489151 | Hepatitis B | Not Applicable | Unknown | December 2007 | China ... more >> Queen Mary Hospital Recruiting Hong Kong, China Sub-Investigator: Raymond Liang, Prof Sub-Investigator: Yok-Lam Kwong, Prof Sub-Investigator: Wing-Yan Au, Dr Sub-Investigator: Chor-sang Chim, Dr Sub-Investigator: Louis Chow, Dr Sub-Investigator: Chee-Kin Hui, Dr Collapse << |
| NCT01205165 | - | - | Completed | - | - |
| NCT00645294 | Hepatitis B | Phase 1 Phase 2 | Completed | - | Belgium ... more >> Cliniques Universitaries Bruxelles, Belgium, 1200 Germany J.W. Goethe-Universitat Frankfurt, Germany, D-60590 Mid. Hochschule Hannover Kinderklinik Hannover, Germany, D-30625 Kinderklinik der Gutenberg Universitat Mainz, Germany, 55101 Standort Lindwurmstrasse Munchen, Germany, D-80337 Zentrum fur Kinder und Jugendmedizin der Klinikum Wuppertal, Germany, D-42282 Poland Oddzial Chorob Infekcyjnych Dzieci Krakow, Poland, 31-202 Klinika Gastroenterologii Warszawa, Poland, 04-730 United Kingdom King's College Hospital London, England, United Kingdom, SE5 9RY University of Birmingham Birmingham, United Kingdom, B4 6NH Collapse << |
| NCT00347009 | Hepatitis B, Chronic ... more >> Cirrhosis Fibrosis Chronic Hepatitis B Collapse << | Phase 4 | Completed | - | Hong Kong ... more >> GSK Investigational Site Pokfulam, Hong Kong Korea, Republic of GSK Investigational Site Daegu, Korea, Republic of, 700-712 GSK Investigational Site Pusan, Korea, Republic of, 602-739 GSK Investigational Site Seoul, Korea, Republic of, 120-752 GSK Investigational Site Seoul, Korea, Republic of, 135-710 GSK Investigational Site Seoul, Korea, Republic of, 137-701 GSK Investigational Site Sungnam-City, Korea, Republic of, 463-712 Singapore GSK Investigational Site Singapore, Singapore, 169608 Taiwan GSK Investigational Site Kaohsiung, Taiwan, 833 GSK Investigational Site Taipei, Taiwan, 100 GSK Investigational Site Taipei, Taiwan, 114 Vietnam GSK Investigational Site Ho Chi Minh City, Vietnam Collapse << |
| NCT00347009 | - | - | Completed | - | - |
| NCT00324961 | Chronic Hepatitis B | Phase 4 | Completed | - | China, Guangdong ... more >> GSK Investigational Site Guangzhou, Guangdong, China, 510515 GSK Investigational Site Guangzhou, Guangdong, China, 510630 China, Hubei GSK Investigational Site Wuhan, Hubei, China, 430030 China, Jiangsu GSK Investigational Site Nanjing, Jiangsu, China, 210029 China, Jilin GSK Investigational Site Changchun, Jilin, China, 130021 China, Zhejiang GSK Investigational Site Hangzhou, Zhejiang, China, 310003 China GSK Investigational Site Beijing, China, 100011 GSK Investigational Site Beijing, China, 100044 GSK Investigational Site Beijing, China, 100050 GSK Investigational Site Changsha, China, 410008 GSK Investigational Site Chongqing, China, 400038 GSK Investigational Site Chongquin, China, 400038 GSK Investigational Site Jinan, China, 250021 GSK Investigational Site Shanghai, China, 200001 GSK Investigational Site Shanghai, China, 200003 GSK Investigational Site Shanghai, China, 200025 GSK Investigational Site Shanghai, China, 200040 GSK Investigational Site Shanghai, China, 200433 Collapse << |
| NCT00644761 | Hepatitis B | Phase 2 | Completed | - | United States, Alabama ... more >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, California Cedars Sinai Medical Center Los Angeles, California, United States, 90048 California Pacific Medical Center San Francisco, California, United States, 94115 University of California, San Francisco San Francisco, California, United States, 94143 United States, Florida University of Miami Miami, Florida, United States, 33136 United States, Massachusetts Beth Israel Deaconess Medical Center Boston, Massachusetts, United States, 02115 United States, New York NYU Medical Center New York, New York, United States, 10016 Columbia Presbyterian Medical Center New York, New York, United States, 10032 Mayo Clinic Rochester, New York, United States, 55905 United States, Pennsylvania University of Pittsburgh Pittsburgh, Pennsylvania, United States, 15213 United States, Texas Baylor Research Institute Dallas, Texas, United States, 75204 Collapse << |
| NCT00324961 | - | - | Completed | - | - |
| NCT00441974 | - | - | Completed | - | - |
| NCT01329419 | - | - | Completed | - | - |
| NCT01436539 | Chronic Hepatitis B | Phase 4 | Unknown | July 2013 | China ... more >> Beijing Ditan Hospital, Capital Medical University Not yet recruiting Beijing, China, 100015 Principal Investigator: Jun Cheng, post doctor Collapse << |
| NCT01353742 | Hepatitis B, Chronic | Phase 1 | Completed | - | Hong Kong ... more >> GSK Investigational Site Shatin, New Territories, Hong Kong Collapse << |
| NCT00441974 | Chronic Hepatitis B | Phase 4 | Completed | - | China, Guangdong ... more >> GSK Investigational Site Guangzhou, Guangdong, China, 510515 GSK Investigational Site Guangzhou, Guangdong, China, 510630 China, Hubei GSK Investigational Site Wuhan, Hubei, China, 430030 China, Jiangsu GSK Investigational Site Nanjing, Jiangsu, China, 210002 GSK Investigational Site Nanjing, Jiangsu, China, 210003 GSK Investigational Site Nanjing, Jiangsu, China, 210029 China, Jilin GSK Investigational Site Changchun, Jilin, China, 130021 China, Sichuan GSK Investigational Site Chengdu, Sichuan, China, 610041 China, Zhejiang GSK Investigational Site Hangzhou, Zhejiang, China, 310003 China GSK Investigational Site Beijing, China, 100011 GSK Investigational Site Beijing, China, 100044 GSK Investigational Site Beijing, China, 100050 GSK Investigational Site Beijing, China, 100069 GSK Investigational Site Changsha, China, 410008 GSK Investigational Site Changsha, China, 410011 GSK Investigational Site Chongqing, China, 400038 GSK Investigational Site Chongquin, China, 400038 GSK Investigational Site Fuzhou, China, 350025 GSK Investigational Site Jinan, China, 250021 GSK Investigational Site Shanghai, China, 200001 GSK Investigational Site Shanghai, China, 200003 GSK Investigational Site Shanghai, China, 200025 GSK Investigational Site Shanghai, China, 200040 GSK Investigational Site Shanghai, China, 200433 GSK Investigational Site Tianjin, China, 300192 Collapse << |
| NCT02327689 | Hepatitis B, Chronic ... more >> Fibrosis Collapse << | Phase 4 | Unknown | July 2017 | - |
| NCT01329419 | - | - | Completed | - | - |
| 靶点 | Description | IC50 |
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