CAS No.: 1345847-93-9
Altiratinib Catalog No. CSN16259
Synonyms: DCC-2701;DP-5164
Altiratinib is a c-MET/TIE-2/VEGFR inhibitor which effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Smith BD, Kaufman MD, et al. Altiratinib Inhibits Tumor Growth, Invasion, Angiogenesis, and Microenvironment-Mediated Drug Resistance via Balanced Inhibition of MET, TIE2, and VEGFR2. Mol Cancer Ther. 2015 Sep;14(9):2023-34.
- [2] Kwon Y, Smith BD, et al. Effective inhibition of c-MET-mediated signaling, growth and migration of ovarian cancer cells is influenced by the ovarian tissue microenvironment. Oncogene. 2015 Jan 8;34(2):144-53.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1345847-93-9 | 储存条件 |
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| 分子式 | C26H21F3N4O4 | 运输 | 蓝冰 | |
| 分子量 | 510.46 | 别名 | DCC-2701;DP-5164 |
