CAS No.: 1345614-59-6
AM095 Catalog No. CSN17715
AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Swaney JS, Chapman C, et al. Pharmacokinetic and pharmacodynamic characterization of an oral lysophosphatidic acid type 1 receptor-selective antagonist. J Pharmacol Exp Ther. 2011 Mar;336(3):693-700.
- [2] Castelino FV, Seiders J, et al. Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma. Arthritis Rheum. 2011 May;63(5):1405-15.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1345614-59-6 | 储存条件 |
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| 分子式 | C27H23N2NaO5 | 运输 | 蓝冰 | |
| 分子量 | 478.47 | 别名 |
