CAS No.: 1645286-75-4
AZ6102 Catalog No. CSN17985
Synonyms: AZ6102
AZ6102 is a potent TNKS1/2 inhibitor that has 100-fold selectivity against other PARP family enzymes and shows IC50 of 5 nM for Wnt pathway inhibition in DLD-1 cells.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Johannes JW, Almeida L, et al. Pyrimidinone nicotinamide mimetics as selective tankyrase and wnt pathway inhibitors suitable for in vivo pharmacology. ACS Med Chem Lett. 2015 Jan 13;6(3):254-9.
- [2] de Vicente J, Tivitmahaisoon P, et al. Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors. ACS Med Chem Lett. 2015 Aug 4;6(9):1019-24.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1645286-75-4 | 储存条件 |
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| 分子式 | C25H28N6O | 运输 | 蓝冰 | |||||||
| 分子量 | 428.53 | 别名 | AZ6102 | |||||||
| 溶解度 |
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动物实验配方 |
