400-920-2911 sales@csnpharm.cn
CAS No.: 1258392-53-8
Synonyms: AZD5582
AZD5582 is a class of dimeric Smac mimetics as potent IAP antagonist and binds potently to the BIR3 domains of cIAP1, cIAP2, and XIAP (IC50 = 15, 21, and 15 nM, respectively).
生物活性
实验方案
技术信息
CAS号 | 1258392-53-8 | 储存条件 |
|
|||||
分子式 | C58H78N8O8 | 运输 | 蓝冰 | |||||
分子量 | 1015.29 | 别名 | AZD5582 | |||||
溶解度 |
|
动物实验配方 |
Cell Lines | Concentration | Assay Type | Time | Activity Description | Data Sources |
---|
BT549 cells | - | Growth inhibition assay | - | Growth inhibition of human BT549 cells | 24320998 |
MDA-MB-231 cells | - | Growth inhibition assay | 48 h | Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 48 hrs by Alamar Blue assay, GI50=6e-05 μM | 24320998 |
联系我们
官方电话:400-920-2911
二维码
微信公众号 CSN官网