CAS No.: 476159-98-5
AZM475271 Catalog No. CSN18293
Synonyms: M475271
AZM475271 is a potent and selective Src kinase inhibitor with IC50 of 5 nM showing no inhibitory activity on Flt3, KDR, Tie-2.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Ple PA, Green TP, et al. Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of c-Src. J Med Chem. 2004 Feb 12;47(4):871-87.
- [2] Yezhelyev MV, Koehl G, et al. Inhibition of SRC tyrosine kinase as treatment for human pancreatic cancer growing orthotopically in nude mice. Clin Cancer Res. 2004 Dec 1;10(23):8028-36.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 476159-98-5 | 储存条件 |
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| 分子式 | C23H27ClN4O3 | 运输 | 蓝冰 | |
| 分子量 | 442.94 | 别名 | M475271 |
