CAS No.: 958002-33-0
Beclabuvir/贝拉布韦 Catalog No. CSN18886
Synonyms: BMS-791325;BCV
Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02124044 HIV-HCV Phase 2 Completed - United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << NCT03071133 - - Recruiting November 14, 2019 Japan ... more >> Local Institution Recruiting Tokyo, Japan, 1620814 Contact: Site 0001 Collapse << NCT02292966 Hepatitis C, Chronic Phase 4 Withdrawn June 2016 Australia, New South Wales ... more >> St Vincent's Hospital Sydney, New South Wales, Australia, 2010 Westmead Hospital Westmead, New South Wales, Australia, 2145 Collapse << - 更多
- 参考文献
- [1] Gentile I, Zappulo E, et al. Beclabuvir for the treatment of hepatitis C. Expert Opin Investig Drugs. 2015;24(8):1111-21.
- [2] Tatum H, Thuluvath PJ, et al. A randomized, placebo-controlled study of the NS5B inhibitor beclabuvir with peginterferon/ribavirin for HCV genotype 1. J Viral Hepat. 2015 Aug;22(8):658-64.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 958002-33-0 | 储存条件 |
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| 分子式 | C36H45N5O5S | 运输 | 蓝冰 | |
| 分子量 | 659.84 | 别名 | BMS-791325;BCV |
